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ClinicalTrials.gov public records Last synced Sep 6, 2026, 3:27 AM EDT

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Showing 1–24 of 103 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Spondylolysis Clear all
Not listed Not applicable Interventional

SPIRA™-A 3D and HCT/p DBM vs. Medtronic Divergent™-L/Perimeter™ and Recombinant BMP-2

NCT04566874
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Scoliosis
Interventions
ALIF
Device
Lead sponsor
Camber Spine Technologies
Industry
Eligibility
22 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Sep 6, 2026, 3:27 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of the CarboClear Pedicle Screw System

NCT02626624
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Grade 1
Interventions
Implantation of the CarboClear Pedicle Screw System
Device
Lead sponsor
CarboFix Orthopedics Ltd.
Industry
Eligibility
21 Years to 72 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
5
States / cities
Boston, Massachusetts • Rochester, Minnesota • Brooklyn, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 6, 2026, 3:27 AM EDT
Terminated Not applicable Interventional Results available

Dynesys Spinal System Post Market 522 Study

NCT01528072
View directory record Official record
Conditions
Degenerative Spondylolisthesis, Pseudoarthrosis
Interventions
Dynesys Spinal System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years to 80 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
9
States / cities
Belleville, Illinois • Baltimore, Maryland • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Sep 6, 2026, 3:27 AM EDT
Completed No phase listed Observational

Posterior Lateral Fusion (PLF) With Dynesys

NCT00791180
View directory record Official record
Conditions
Spondylolisthesis
Interventions
Not listed
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2011 · Synced Sep 6, 2026, 3:27 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Spine Registration Using 3D Scanning

NCT05195580
View directory record Official record
Conditions
Spinal Fusion, Spinal Stenosis, Scoliosis, Spondylolisthesis
Interventions
Optical 3D Scanner
Device
Lead sponsor
Advanced Scanners Inc.
Industry
Eligibility
Not listed
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Round Rock, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 6, 2026, 3:27 AM EDT
Recruiting Not applicable Interventional

Bone Stimulator for Spondylolysis

NCT06666608
View directory record Official record
Conditions
Spondylolysis, Symptomatic Spondylolysis, Athletes
Interventions
Bone Stimulator, Standard of Care Spondylolysis Treatment
Device · Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
16 Years to 40 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 6, 2026, 3:27 AM EDT
Completed Not applicable Interventional

A Clinical Study to Evaluate Safety and Performance of PEEK-OPTIMA™ HA Enhanced.

NCT04416321
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
Interventions
Surgery with the Keos Lumbar Interbody Fusion Device
Device
Lead sponsor
Invibio Ltd
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 6, 2026, 3:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease

NCT03733626
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Lumbar Radiculopathy, Lumbar Spinal Stenosis, Lumbar Disc Disease
Interventions
ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system, Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system
Combination Product
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 6, 2026, 3:27 AM EDT
Recruiting No phase listed Observational

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

NCT05648474
View directory record Official record
Conditions
Intervertebral Disc Degeneration, Stenosis, Spinal, Spondylolisthesis, Spinal Deformity, Spinal Instability
Interventions
Somatosensory evoked potential [SSEP] intraoperative monitoring
Diagnostic Test
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 6, 2026, 3:27 AM EDT
Completed No phase listed Observational

Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability

NCT00726310
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis
Interventions
SpineLink® , SpineLink® II
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2009
U.S. locations
2
States / cities
San Diego, California • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Sep 6, 2026, 3:27 AM EDT
Terminated Not applicable Interventional Results available

Clinical Outcomes of the Trinica(R) Anterior Lumbar Plate: Fixed Screws vs. Variable Screws

NCT00762723
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
Trinica Anterior Lumbar Plate System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
Daphne, Alabama • Mobile, Alabama • San Bernardino, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Sep 6, 2026, 3:27 AM EDT
Not listed No phase listed Observational

Burst Biologics Spinal Fusion Registry

NCT03064802
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylitis, Spondylolisthesis, Herniated Disk
Interventions
BioBurst Fluid, Burst Allograft
Device
Lead sponsor
Burst Biologics
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
4
States / cities
Carrollton, Georgia • Paducah, Kentucky • Bethesda, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2019 · Synced Sep 6, 2026, 3:27 AM EDT
Not listed Phase 1Phase 2 Interventional

Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery

NCT00798902
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis
Interventions
Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules, Iliac crest autograft
Device · Other
Lead sponsor
BioSurface Engineering Technologies, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
6
States / cities
Durango, Colorado • Washington D.C., District of Columbia • Kansas City, Kansas + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2012 · Synced Sep 6, 2026, 3:27 AM EDT
Not listed Not applicable Interventional

Post-market Surveillance Study of FLXfit™ TLIF Interbody Fusion Device

NCT02805985
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
Interventions
FLXfit™ TLIF Interbody Fusion Device
Device
Lead sponsor
Expanding Orthopedics Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Sep 6, 2026, 3:27 AM EDT
Active, not recruiting Not applicable Interventional

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

NCT03570801
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Interventions
Expert Panel Review
Other
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
662 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
16
States / cities
Scottsdale, Arizona • San Francisco, California • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 6, 2026, 3:27 AM EDT
Not listed No phase listed Observational

MIS ReFRESH: Robotic vs. Freehand Minimally Invasive Spinal Surgeries

NCT02057744
View directory record Official record
Conditions
Degenerative Spine Disease, Spondylolisthesis, Spondylosis
Interventions
Not listed
Lead sponsor
Mazor Robotics
Industry
Eligibility
21 Years to 99 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
9
States / cities
Celebration, Florida • Jacksonville, Florida • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 6, 2026, 3:27 AM EDT
Not listed Not applicable Interventional

Study of Nucel for One and Two Level Lumbar Interbody Fusion

NCT02808234
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Spondylosis
Interventions
One or two level lumbar interbody fusion surgery, Nucel
Procedure · Other
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
3
States / cities
Tampa, Florida • Shreveport, Louisiana • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Sep 6, 2026, 3:27 AM EDT
Enrolling by invitation No phase listed Observational

A Prospective Analysis of the Efficacy of Allosync Expand and Autograft Bone Graft in Open Lumbar Spinal Fusion

NCT06415110
View directory record Official record
Conditions
Spondylolisthesis, Grade 1
Interventions
Allosync Expand
Device
Lead sponsor
Research Source
Network
Eligibility
22 Years and older
Enrollment
40 participants
Timeline
2024 – 2027
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 6, 2026, 3:27 AM EDT
Recruiting No phase listed Observational

Thoracic-Lumbar Arthrodesis- Implanet Jazz

NCT05366140
View directory record Official record
Conditions
Spondylolisthesis, Spinal Stenosis, Degenerative Disease
Interventions
Prospective follow-up of patients who have received instrumented lumbar arthrodesis supplemented the Implanet Jazz System(TM)
Other
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 100 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 6, 2026, 3:27 AM EDT
Terminated Not applicable Interventional Results available

AccuLIF® PROSPECTIVE PATIENT OUTCOMES STUDY

NCT02704689
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Grade 1, Retrolisthesis
Interventions
AccuLIF expandable TLIF cage
Device
Lead sponsor
VB Spine, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 23, 2018 · Synced Sep 6, 2026, 3:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis

NCT00405691
View directory record Official record
Conditions
Low Back Pain, Leg Pain, Spondylolisthesis, Lumbar Spinal Stenosis
Interventions
"TOPS System" - Total Posterior Arthroplasty Implant
Device
Lead sponsor
Impliant, Ltd.
Industry
Eligibility
40 Years to 75 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
16
States / cities
Beverly Hills, California • Daly City, California • New Haven, Connecticut + 12 more
Source: ClinicalTrials.gov public record
Updated May 17, 2011 · Synced Sep 6, 2026, 3:27 AM EDT
Recruiting Not applicable Interventional

Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device

NCT06355791
View directory record Official record
Conditions
Degenerative Conditions of the Lumbar Spine, Lumbar Spinal Stenosis, Spondylolisthesis
Interventions
Minuteman G5 Device
Device
Lead sponsor
Spinal Simplicity LLC
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
6
States / cities
Newnan, Georgia • Indianapolis, Indiana • Kansas City, Kansas + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 6, 2026, 3:27 AM EDT
Terminated Not applicable Interventional Results available

Slotted Hole Versus Fixed Hole C-Tek

NCT00585923
View directory record Official record
Conditions
Herniated Disc, Radiculopathy, Spondylolysis
Interventions
Fixed hole C-Tek™ Plate, Slotted hole C-Tek™ Plate
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Sep 6, 2026, 3:27 AM EDT
Suspended Not applicable Interventional

Pedicle Osteotomy for Stenosis Trial

NCT03381677
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Spondylolisthesis, Grade 1, Neurogenic Claudication
Interventions
Pedicle Lengthening Osteotomy with Altum® Device, Control
Device
Lead sponsor
Innovative Surgical Designs
Industry
Eligibility
40 Years to 80 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Bryn Mawr, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2020 · Synced Sep 6, 2026, 3:27 AM EDT