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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Spondylolysis Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Multimodal Analgesia Versus Routine Care Pain Management

NCT01861743
View directory record Official record
Conditions
Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
Interventions
Multimodal Analgesia, Patient controlled analgesia
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Jul 22, 2026, 3:36 AM EDT
Not listed Not applicable Interventional

Supine vs. Upright Weight Bearing MRI in the Evaluation of Patients With Lumbar Spondylolisthesis

NCT02958241
View directory record Official record
Conditions
Spondylolisthesis
Interventions
MRI
Other
Lead sponsor
Texas Back Institute
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Nov 7, 2016 · Synced Jul 22, 2026, 3:36 AM EDT
Completed No phase listed Observational

Back in the Game: An Immediate Functional Progression Program in Athletes With a Spondylolysis.

NCT03237104
View directory record Official record
Conditions
Low Back Pain, Spondylosis
Interventions
Immediate PT
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
10 Years to 19 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
5
States / cities
Columbus, Ohio • Dublin, Ohio • New Albany, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Jul 22, 2026, 3:36 AM EDT
Terminated Phase 3 Interventional Results available

INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine

NCT01415908
View directory record Official record
Conditions
Lumbar Spine Degeneration
Interventions
INFUSE Bone Graft, Iliac Crest Bone Graft
Device · Other
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
5
States / cities
Mesa, Arizona • Los Angeles, California • Gulf Breeze, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Jul 22, 2026, 3:36 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief

NCT03514277
View directory record Official record
Conditions
Low Back Pain, Lumbosacral Radiculopathy, Lumbar Disc Degeneration, Lumbar Disc Herniation, Stenosis, Spondylolisthesis, Spondylolysis, Deformity of Spine
Interventions
Exparel, Bupivacaine
Drug
Lead sponsor
Virtua Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Mount Holly, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Jul 22, 2026, 3:36 AM EDT
Terminated No phase listed Observational

Aspen Spinous Process Fixation System for Use in PLF in Patients With Spondylolisthesis

NCT01560273
View directory record Official record
Conditions
Spondylolisthesis
Interventions
Aspen Spinous Process Fixation Device
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
50 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
5
States / cities
Phoenix, Arizona • Mission Viejo, California • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Jul 22, 2026, 3:36 AM EDT
Completed No phase listed Observational

Rest Before Physical Therapy in Adolescents With Active Spondylolysis and Spondylolisthesis

NCT02332200
View directory record Official record
Conditions
Spondylolysis, Spondylolisthesis, Low Back Pain
Interventions
Physical Therapy
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
4
States / cities
Columbus, Ohio • Dublin, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2022 · Synced Jul 22, 2026, 3:36 AM EDT
Terminated Not applicable Interventional Results available

Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar Surgery

NCT04007094
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylosis, Spondylolisthesis
Interventions
ViviGen Cellular Bone Matrix
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jul 22, 2026, 3:36 AM EDT
Recruiting No phase listed Observational

Adult Patient Outcomes After Spine Surgery With Fibergraft BG Putty/Viper Prime

NCT06704906
View directory record Official record
Conditions
Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
Interventions
Use of Viper Prime/Expedium system with Fibergraft BG Putty
Device
Lead sponsor
Nitin Agarwal
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jul 22, 2026, 3:36 AM EDT
Active, not recruiting Not applicable Interventional

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

NCT03570801
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Interventions
Expert Panel Review
Other
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
662 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
16
States / cities
Scottsdale, Arizona • San Francisco, California • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Jul 22, 2026, 3:36 AM EDT
Enrolling by invitation No phase listed Observational

The Course of Hip Flexion Weakness Following LLIF or ALIF

NCT04204135
View directory record Official record
Conditions
Degenerative Disc Disease, Herniated Nucleus Pulposus, Spondylolisthesis
Interventions
LLIF or ALIF procedures
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
Up to 65 Years
Enrollment
22 participants
Timeline
2018 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Jul 22, 2026, 3:36 AM EDT
Recruiting No phase listed Observational

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

NCT05648474
View directory record Official record
Conditions
Intervertebral Disc Degeneration, Stenosis, Spinal, Spondylolisthesis, Spinal Deformity, Spinal Instability
Interventions
Somatosensory evoked potential [SSEP] intraoperative monitoring
Diagnostic Test
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Jul 22, 2026, 3:36 AM EDT
Terminated Not applicable Interventional

Dynamic Stabilization for Lumbar Spinal Stenosis With Stabilimax NZ® Dynamic Spine Stabilization System

NCT00529997
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Stabilimax NZ® Dynamic Spine Stabilization System
Device
Lead sponsor
Applied Spine Technologies
Industry
Eligibility
21 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
19
States / cities
Phoenix, Arizona • Los Angeles, California • Oceanside, California + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2010 · Synced Jul 22, 2026, 3:36 AM EDT
Terminated Not applicable Interventional

Effectiveness of Lumbar Fusion When NanOss Bioactive Is Used With Posterolateral Gutter Fusions

NCT01452516
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
nanOss Bioactive Bone void filler, Interbody FCage
Device
Lead sponsor
Pioneer Surgical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
7
States / cities
Beverly Hills, California • La Jolla, California • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Jul 22, 2026, 3:36 AM EDT
Completed Phase 4 Interventional Results available

Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia

NCT01325493
View directory record Official record
Conditions
Idiopathic Scoliosis, Spondylolisthesis
Interventions
Ketamine, Normal Saline
Drug
Lead sponsor
Julia Finkel
Other
Eligibility
10 Years to 18 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Jul 22, 2026, 3:36 AM EDT
Enrolling by invitation No phase listed Observational

A Prospective Analysis of the Efficacy of Allosync Expand and Autograft Bone Graft in Open Lumbar Spinal Fusion

NCT06415110
View directory record Official record
Conditions
Spondylolisthesis, Grade 1
Interventions
Allosync Expand
Device
Lead sponsor
Research Source
Network
Eligibility
22 Years and older
Enrollment
40 participants
Timeline
2024 – 2027
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 22, 2026, 3:36 AM EDT
Not listed Not applicable Interventional

SPIRA™-A 3D and HCT/p DBM vs. Medtronic Divergent™-L/Perimeter™ and Recombinant BMP-2

NCT04566874
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Scoliosis
Interventions
ALIF
Device
Lead sponsor
Camber Spine Technologies
Industry
Eligibility
22 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Jul 22, 2026, 3:36 AM EDT
Terminated Not applicable Interventional Results available

Dynesys Spinal System Post Market 522 Study

NCT01528072
View directory record Official record
Conditions
Degenerative Spondylolisthesis, Pseudoarthrosis
Interventions
Dynesys Spinal System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years to 80 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
9
States / cities
Belleville, Illinois • Baltimore, Maryland • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Jul 22, 2026, 3:36 AM EDT
Completed Not applicable Interventional

A Clinical Study to Evaluate Safety and Performance of PEEK-OPTIMA™ HA Enhanced.

NCT04416321
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
Interventions
Surgery with the Keos Lumbar Interbody Fusion Device
Device
Lead sponsor
Invibio Ltd
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Jul 22, 2026, 3:36 AM EDT
Not listed Phase 1Phase 2 Interventional

Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery

NCT00798902
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis
Interventions
Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules, Iliac crest autograft
Device · Other
Lead sponsor
BioSurface Engineering Technologies, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
6
States / cities
Durango, Colorado • Washington D.C., District of Columbia • Kansas City, Kansas + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2012 · Synced Jul 22, 2026, 3:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease

NCT03733626
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Lumbar Radiculopathy, Lumbar Spinal Stenosis, Lumbar Disc Disease
Interventions
ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system, Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system
Combination Product
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Jul 22, 2026, 3:36 AM EDT
Not listed Phase 1Phase 2 Interventional

Safety Evaluation of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion

NCT04378543
View directory record Official record
Conditions
Degenerative Spondylolisthesis
Interventions
ART352-L
Biological
Lead sponsor
Ankasa Regenerative Therapeutics, Inc.
Industry
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Los Angeles, California • Rochester, Minnesota • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Jul 22, 2026, 3:36 AM EDT
Completed Phase 3 Interventional

Greenwich Lumbar Stenosis SLIP Study

NCT00109213
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis
Interventions
Lumbar Laminectomy with Instrumented Pedicle Screw Fusion, Lumbar Laminectomy
Procedure
Lead sponsor
Greenwich Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
5
States / cities
Greenwich, Connecticut • Boston, Massachusetts • Burlington, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Jul 22, 2026, 3:36 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of the CarboClear Pedicle Screw System

NCT02626624
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Grade 1
Interventions
Implantation of the CarboClear Pedicle Screw System
Device
Lead sponsor
CarboFix Orthopedics Ltd.
Industry
Eligibility
21 Years to 72 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
5
States / cities
Boston, Massachusetts • Rochester, Minnesota • Brooklyn, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Jul 22, 2026, 3:36 AM EDT