Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 25, 2026, 11:01 AM EDT

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Showing 1–10 of 10 matching trials from the live ClinicalTrials.gov search.
Conditions
Substance Use Disorder (SUD), Opioid Use Disorders, Stimulant Overdose, Overdose Risk, Alcohol Use Disorder
Interventions
Recovery Management Checkups (RMC) delivered by community-based agencies (RMC adopters), Recovery Management Checkups (RMC) delivered by staff under the research team (RMC by research staff)
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Stimulant Overdose
Interventions
Aim 1 (case-cohort study), Aim 2 (case-crossover study), Aim 3 (cohort study)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
634,939 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Naltrexone for Overdose Prevention

NCT06633900
Conditions
Overdose Accidental
Interventions
IM naltrexone, Usual Care
Drug · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Kentucky Women's Justice Community Overdose Innovation Network - Phase II

NCT07179614
Conditions
Overdose Risk, Opioid Use Disorder, Stimulant Use Disorders
Interventions
Overdose Prevention Intervention Package (OPIP)
Behavioral
Lead sponsor
Michele Staton
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
3
States / cities
Barbourville, Kentucky • Harlan, Kentucky • Hyden, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

Beginning Early and Assertive Treatment for Methamphetamine Use Disorder

NCT06033365
Conditions
Methamphetamine Use Disorder
Interventions
care navigation
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Stimulant Overdose, Overdose Accidental, Overdose Cocaine, Overdose Methamphetamine
Interventions
Not listed
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Results available

THRIVE: Culturally AdapTed Harm Reduction Intervention

NCT06609278
Conditions
Opioid Use, Stimulant Use
Interventions
harm reduction intervention
Behavioral
Lead sponsor
Brittany Miller-Roenigk
Other
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Louisville, Kentucky • Cincinnati, Ohio
Not yet recruiting Not applicable Interventional

Remote Intervention to Prevent Overdose

NCT07128485
Conditions
Accidental Overdose of Opiate
Interventions
Overdose prevention resources, Overdose prevention education
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder, Stimulant Use Disorder, Substance Use Disorder
Interventions
PATH (Peer Advanced Training for total Health)
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Opiate Overdose, Fentanyl Overdose, Harm Reduction
Interventions
Fentanyl Test Strips
Behavioral
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
18 Years and older
Enrollment
653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbus, Ohio