- Conditions
- Opioid Use Disorder, Stimulant Use Disorder
- Interventions
- Suvorexant (dual orexin receptor antagonist), Placebo
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
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Showing 25–48
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- Conditions
- PrEP Uptake, Stimulant Abuse, Adherence, Medication
- Interventions
- Pepped on PrEP Package
- Behavioral
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Stimulant Use Disorder, Substance-related Disorders
- Interventions
- Repetitive transcranial magnetic stimulation (rTMS)
- Device
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- HIV (Human Immunodeficiency Virus)
- Interventions
- Not listed
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 30 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 4
- States / cities
- San Francisco, California • Atlanta, Georgia • Baltimore, Maryland + 1 more
- Conditions
- Stimulant Use Disorder
- Interventions
- Repetitive transcranial magnetic stimulation (rTMS), Sham rTMS
- Device
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Substance Related Disorders
- Interventions
- Just Care for Families (JCFF), Just Care for Families (JCFF) App, Just Care for Families (JCFF) App Feedback
- Behavioral
- Lead sponsor
- Chestnut Health Systems
- Other
- Eligibility
- Not listed
- Enrollment
- 254 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Eugene, Oregon
- Conditions
- Methamphetamine Use Disorder, Human Immunodeficiency Virus (HIV)
- Interventions
- Psilocybin 5 mg, Psilocybin 25 mg, Motivational Support
- Drug · Behavioral
- Lead sponsor
- Nicky Mehtani, MD, MPH
- Other
- Eligibility
- 25 Years to 64 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Opioid Use, Stimulant Use
- Interventions
- harm reduction intervention
- Behavioral
- Lead sponsor
- Brittany Miller-Roenigk
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 3
- States / cities
- Louisville, Kentucky • Cincinnati, Ohio
- Conditions
- HIV, Stimulant Use Disorder, Justice Involved Populations, HIV Prevention
- Interventions
- DynamiCare, Patient Navigation (PN)
- Device · Behavioral
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- New Haven, Connecticut • Dallas, Texas
- Conditions
- Stimulant Dependence, Methamphetamine-dependence, Addiction, Drug
- Interventions
- Transcranial Magnetic Stimulation--DPFC first, MPFC second, Transcranial Magnetic Stimulation--MPFC first, DPFC second
- Device
- Lead sponsor
- Ryan M. Carnahan
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Methamphetamine Abuse, Substance Use Disorders, Stimulant Dependence, Methamphetamine-dependence, Stimulant Use, Transcranial Magnetic Stimulation
- Interventions
- Real Repetitive transcranial magnetic stimulation, Sham Repetitive transcranial magnetic stimulation, Methamphetamine visual cues, Neutral visual cues
- Device · Behavioral
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Cannabis Use Disorder, Stimulant Use Disorder, Opioid Use Disorder, Tobacco Use Disorder, Alcohol Use Disorder, Sedative, Hypnotic, or Anxiolytic Use Disorders
- Interventions
- Emotional Brain Training, Standard addiction counseling and medical therapy
- Behavioral · Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- San Bernardino, California
- Conditions
- HIV Infections, Methamphetamine-dependence, Methamphetamine Abuse
- Interventions
- Not listed
- Lead sponsor
- Florida International University
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Behavioral Intervention, Viral Suppression of HIV Infection, ART Adherence
- Interventions
- reSTART Objective Adherence Self-Monitoring and Postive Affect mHealth Intervention, urine tenofovir point-of-care self-test
- Behavioral · Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 70 Years · Male only
- Enrollment
- 270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Stimulant Use Disorders
- Interventions
- Cultually Adapted Contingency Management (CM), Basic Contingency Management (CM)
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2028 – 2030
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Medication Adherence, HIV Prevention, Stimulant Use
- Interventions
- PARTI, Attention-Control, Contingency Management for PrEP Adherence
- Behavioral
- Lead sponsor
- Florida International University
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 239 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2026
- U.S. locations
- 2
- States / cities
- San Francisco, California • Miami, Florida
- Conditions
- Stimulant Use, Human Immunodeficiency Virus (HIV), Depression
- Interventions
- ARTEMIS, Contingency management for Antiretroviral (ARV) adherence
- Behavioral
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 59 Years
- Enrollment
- 189 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Interventions
- NRP104
- Drug
- Lead sponsor
- New River Pharmaceuticals
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
- Interventions
- Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
- Other
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 338 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Little Rock, Arkansas
- Conditions
- Stimulant Use, Relapse, Cognitive Function, ADHD
- Interventions
- Contrave 8Mg-90Mg Extended-Release Tablet, Bupropion
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Nicotine Dependence
- Interventions
- Nicotine, Progesterone
- Other
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 40 Years · Female only
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2016
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Opioid Use Disorder, Injection Related Infections, Stimulant Use Disorder
- Interventions
- Integrated Infectious Diseases and Substance Use Disorder Clinic (IC)
- Behavioral
- Lead sponsor
- Elana Rosenthal
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 304 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 4
- States / cities
- Washington D.C., District of Columbia • Atlanta, Georgia • Baltimore, Maryland + 1 more
- Conditions
- Cocaine Dependence, Methamphetamine Dependence, Nicotine Dependence
- Interventions
- Smoking-cessation treatment
- Other
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 538 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 12
- States / cities
- Tucson, Arizona • Rancho Cucamonga, California • Tarzana, California + 9 more
- Conditions
- Cocaine Use Disorder, Methamphetamine Abuse, Cocaine Dependence, Methamphetamine Dependence, Stimulant Use, Stimulant Abuse, Methamphetamine Use Disorder, Cocaine Abuse, Stimulant Use Disorder
- Interventions
- rTMS, Sham (Placebo)
- Device
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 129 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 4
- States / cities
- Winston-Salem, North Carolina • Charleston, South Carolina • Dallas, Texas + 1 more