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Showing 1–24 of 76 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Stool Microbiome Clear all
Enrolling by invitation Phase 1 Interventional

Fecal Microbiome Transplant

NCT02636517
View directory record Official record
Conditions
Clostridium Difficile, Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
Interventions
Fecal Microbiota Transplant
Biological
Lead sponsor
Judith Kelsen
Other
Eligibility
3 Years to 21 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Microbiota Diversity and Composition and Polyphenol Bioavailability

NCT02677649
View directory record Official record
Conditions
Fecal Microbiota
Interventions
cranberry, placebo
Other
Lead sponsor
Tufts University
Other
Eligibility
20 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 3, 2026, 9:41 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

My Baby Biome: Infant Stool Samples for Microbiome Health (MBB)

NCT05472688
View directory record Official record
Conditions
Dysbiosis
Interventions
Not listed
Lead sponsor
Persephone Biosciences
Industry
Eligibility
0 Months to 2 Months
Enrollment
430 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 3, 2026, 9:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract

NCT05603650
View directory record Official record
Conditions
Oral Bacterial Infection, Oral Infection, Microbial Colonization, Viral Infection
Interventions
Lumineux Oral Essentials rinse, Listerine rinse
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Feasibility of Rice Bran Supplementation in Nicaraguan Children

NCT02615886
View directory record Official record
Conditions
Dietary Rice Bran Supplementation
Interventions
Observational Control, Rice bran
Other · Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
4 Months to 13 Months
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Sep 3, 2026, 9:41 AM EDT
Active, not recruiting Phase 2 Interventional

Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy

NCT03420482
View directory record Official record
Conditions
Hepatic Encephalopathy
Interventions
Fecal Microbiota Transplant (FMT) oral capsules, Placebo oral capsule
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 3, 2026, 9:41 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

NCT05821309
View directory record Official record
Conditions
Constipation
Interventions
PEG 3350, PEG-3350 with electrolytes, Glycerin
Drug
Lead sponsor
Indiana University
Other
Eligibility
2 Years to 18 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Phase 1 Interventional

Fecal Microbiota Transplantation in HIV

NCT02256592
View directory record Official record
Conditions
HIV
Interventions
Fecal Microbiota
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Sep 3, 2026, 9:41 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Microbiome in Colorectal Cancer Onset and Progression

NCT05368688
View directory record Official record
Conditions
Colorectal Cancer, Tumor, CRC, GI Cancer, Gastrointestinal Cancer
Interventions
Not listed
Lead sponsor
Viome
Industry
Eligibility
50 Years to 80 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Dec 26, 2022 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Stool Microbiome Using HyGIeaCare Prep

NCT04264923
View directory record Official record
Conditions
Stool Microbiome
Interventions
HyGIeaCare Prep
Other
Lead sponsor
HyGIeaCare, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Sep 3, 2026, 9:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health

NCT07787026
View directory record Official record
Conditions
Mixed Fiber Supplementation for Healthy Adults
Interventions
Prebiotic, Placebo
Dietary Supplement
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 3, 2026, 9:41 AM EDT
Recruiting No phase listed Observational

Development and Analysis of a Stool Bank for Cancer Patients

NCT04291755
View directory record Official record
Conditions
Carcinoma, Non-Small-Cell Lung, Carcinoma, Colorectal
Interventions
Pembrolizumab Injection
Drug
Lead sponsor
Persephone Biosciences
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
2
States / cities
Fountain Valley, California • Winter Haven, Florida
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 3, 2026, 9:41 AM EDT
Recruiting Phase 1Phase 2 Interventional

Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis

NCT05333471
View directory record Official record
Conditions
Chronic Granulomatous Disease-associated Colitis
Interventions
MTP 101-LF
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
10 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 3, 2026, 9:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Metabolome and Microbiomic in Fecal Samples

NCT00938028
View directory record Official record
Conditions
Infant
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Months to 20 Months
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2009 · Synced Sep 3, 2026, 9:41 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

ARGONAUT: Stool and Blood Sample Bank for Cancer Patients

NCT04638751
View directory record Official record
Conditions
Non-small Cell Lung Cancer, Colorectal Cancer, Triple Negative Breast Cancer, Pancreas Cancer
Interventions
Immunotherapy, Chemotherapy, CRC surgical resection, Colonoscopy
Drug · Procedure
Lead sponsor
Persephone Biosciences
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
10
States / cities
Orange, California • San Diego, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistant Starch Blend Gastrointestinal Impact

NCT03983772
View directory record Official record
Conditions
Quality of Life, Health, Subjective
Interventions
RS blend, Placebo
Dietary Supplement · Other
Lead sponsor
Metagenics, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Gig Harbor, Washington
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Sep 3, 2026, 9:41 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Safety and Efficacy of Fecal Microbiome Transplantation (FMT) in the Treatment of Antibiotic Dependent Pouchitis (ADP)

NCT02782325
View directory record Official record
Conditions
Pouchitis
Interventions
Active FMT, then open label FMT, Placebo FMT, then open label FMT
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Soluble Corn Fiber on Gastrointestinal Tolerance and Fecal Microbiome in Healthy Children

NCT05213494
View directory record Official record
Conditions
Gastrointestinal Tolerance
Interventions
Inulin, soluble corn fiber
Other
Lead sponsor
Tate & Lyle
Industry
Eligibility
3 Years to 9 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 27, 2022 · Synced Sep 3, 2026, 9:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

GI Tract Biomarkers in Infants With Different Diets

NCT03751137
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Not listed
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Weeks to 3 Months
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 3, 2026, 9:41 AM EDT
Completed No phase listed Observational

Isolation and Characterization of Multiple Microbial Species From Diverse Healthy Adults

NCT05150184
View directory record Official record
Conditions
Human Microbiome
Interventions
Non-interventional
Other
Lead sponsor
Danisco
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Autologous Fecal Microbiota Transplantation to Prevent Antibiotic Resistant Bacteria Colonization

NCT03061097
View directory record Official record
Conditions
Antibiotic Resistant Strain
Interventions
Autologous fecal microbiota transplant (Auto-FMP Enema), Placebo Enema Preparation
Biological · Other
Lead sponsor
Microbiome Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ButyraGen™, Short Chain Fatty Acids and Gut Microbiome

NCT05601635
View directory record Official record
Conditions
Healthy
Interventions
ButyraGen™
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Sep 3, 2026, 9:41 AM EDT
Active, not recruiting Not applicable Interventional

The Beans to Enrich the Gut Microbiome vs. Obesity's Negative Effects (BE GONE) Trial

NCT02843425
View directory record Official record
Conditions
Colorectal Cancer Prevention
Interventions
Regular Diet, Navy Beans (Canned)
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
30 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 3, 2026, 9:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin

NCT03477825
View directory record Official record
Conditions
Sebum Production, Stool Microbiome, Transepidermal Water Loss, Facial Brrightness, Erythema, Wrinkles, Facial Shine
Interventions
Placebo Oral Tablet, Rubia Cordifolia, Triphala
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 60 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Sep 3, 2026, 9:41 AM EDT