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Showing 1–24 of 74 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Stool Microbiome Clear all
Completed No phase listed Observational

Comparison of Gut Microbiota, Inflammation and Symptoms Following Allogeneic HSCT

NCT02398708
View directory record Official record
Conditions
Graft vs Host Disease, Graft Versus Host Disease, Hematopoietic Stem Cell Transplantation, Peripheral Blood Stem Cell Transplantation
Interventions
Questionnaires, Blood Sample, Stool Sample, Clinical data
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Jun 27, 2026, 2:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Sample Collection From Healthy Volunteers for Assay Optimization

NCT03538600
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
3 Years to 80 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2043
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated Phase 2 Interventional Results available

Penn Microbiome Therapy (PMT) for Severe-Clostridium Difficile Infection (CDI)

NCT03970200
View directory record Official record
Conditions
Severe Clostridium Difficile Infection, Severe-Complicated/Fulminant Clostridium Difficile Infection
Interventions
Penn Microbiome Therapy - 001, Penn Microbiome Therapy - 002, Penn Microbiome Therapy - 003, Antibiotics
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 29, 2023 · Synced Jun 27, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Weizmannia (Bacillus) Coagulans JBI-YZ6.3 on Gut Health and Fecal Microbiome Changes

NCT07388264
View directory record Official record
Conditions
Gastrointestinal Symptoms, Constipation, Gut Health, Gastrointestinal Function
Interventions
Weizmannia (Bacillus) coagulans JBI-YZ6.3, Placebo
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Autologous Fecal Therapy

NCT02046525
View directory record Official record
Conditions
Infectious Disease of Digestive Tract
Interventions
Autologous fecal microbiota therapy, Placebo
Biological · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Stool Microbiome Using HyGIeaCare Prep

NCT04264923
View directory record Official record
Conditions
Stool Microbiome
Interventions
HyGIeaCare Prep
Other
Lead sponsor
HyGIeaCare, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Time-restricted Eating on Nutrient Absorption in Healthy Adults

NCT04877262
View directory record Official record
Conditions
Digestibility
Interventions
weight maintenance diet (WMD)
Other
Lead sponsor
Florida State University
Other
Eligibility
20 Years to 45 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

OptiCal Study -Optimizing Fecal Calprotectin Monitoring: a Clinical Study Comparing CalproLab Against PhiCal and Evaluating Its Association With the Gut Microbiome

NCT03051204
View directory record Official record
Conditions
Crohn Disease, Ulcerative Colitis, Irritable Bowel Syndrome, Celiac Disease, Healthy
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Years to 65 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Microbiota Diversity and Composition and Polyphenol Bioavailability

NCT02677649
View directory record Official record
Conditions
Fecal Microbiota
Interventions
cranberry, placebo
Other
Lead sponsor
Tufts University
Other
Eligibility
20 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation

NCT03907501
View directory record Official record
Conditions
Human Microbiome
Interventions
Synbiotic, Probiotic, Placebo
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated No phase listed Observational

Gut Microbiome in Fecal Samples From Patients With Metastatic Cancer Undergoing Chemotherapy or Immunotherapy

NCT02960282
View directory record Official record
Conditions
Metastatic Carcinoma, Stage IV Colorectal Cancer, Stage IVA Colorectal Cancer, Stage IVB Colorectal Cancer
Interventions
Biospecimen Collection, Laboratory Biomarker Analysis
Procedure · Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Not yet recruiting Phase 1 Interventional

Familial Fecal Microbiota Transplant for the Treatment of Subjects With Autism Spectrum Disorders

NCT04630847
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Fecal Microbiota Transplant
Biological
Lead sponsor
ProgenaBiome
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing Uniqueness of Inflammatory Bowel Disease Related Microbiome-derived Biomarkers

NCT05640583
View directory record Official record
Conditions
Irritable Bowel Disease
Interventions
Hygieacare System
Device
Lead sponsor
HyGIeaCare, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Jun 27, 2026, 2:22 AM EDT
Recruiting Phase 1Phase 2 Interventional

Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis

NCT05333471
View directory record Official record
Conditions
Chronic Granulomatous Disease-associated Colitis
Interventions
MTP 101-LF
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
10 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Patients & Effect of Antibiotics

NCT03098485
View directory record Official record
Conditions
Microbiota, Anti-bacterial Agents
Interventions
Levofloxacin, Azithromycin, Cefpodoxime
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational

Reproducibility of a Fecal Occult Blood Test Device for Gut Microbiota Analyses

NCT01194687
View directory record Official record
Conditions
Normal Physiology
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Jun 27, 2026, 2:22 AM EDT
Active, not recruiting Phase 2 Interventional

PMT for MDRO Decolonization

NCT05632315
View directory record Official record
Conditions
Multidrug Resistant Bacterial Infection, Enterobacteriaceae Infections, Pseudomonas Aeruginosa, VRE Infection, Methicillin-resistant Staphylococcus Aureus
Interventions
PMT
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Atlanta, Georgia • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 27, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Aimmune Longitudinal Collaboration Study

NCT07218640
View directory record Official record
Conditions
Stool Spore Colony Forming Units, Microbiome Composition, Dietary Fiber, Stress
Interventions
Chia seeds
Other
Lead sponsor
Aimmune Therapeutics, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Ambler, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Microbiome in Colorectal Cancer Onset and Progression

NCT05368688
View directory record Official record
Conditions
Colorectal Cancer, Tumor, CRC, GI Cancer, Gastrointestinal Cancer
Interventions
Not listed
Lead sponsor
Viome
Industry
Eligibility
50 Years to 80 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Dec 26, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Recruiting No phase listed Observational

Development and Analysis of a Stool Bank for Cancer Patients

NCT04291755
View directory record Official record
Conditions
Carcinoma, Non-Small-Cell Lung, Carcinoma, Colorectal
Interventions
Pembrolizumab Injection
Drug
Lead sponsor
Persephone Biosciences
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
2
States / cities
Fountain Valley, California • Winter Haven, Florida
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated Phase 1Phase 2 Interventional

Effects of Probiotic on Inflammation and Microbiota in Patients With NASH

NCT03511365
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease, Probiotics MeSH Descriptor Data 2018, Interleukin-17 MeSH Descriptor Data 2018
Interventions
Probiotic Formulation VSL#3
Biological
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Impact of Proton Pump Inhibitors on the Fecal Microbiome

NCT01822977
View directory record Official record
Conditions
Healthy, Clostridium Difficile Infection
Interventions
omeprazole
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Novel Fecal Sample Collection Method for Metagenomic Analyses

NCT05172414
View directory record Official record
Conditions
Healthy
Interventions
No intervention
Other
Lead sponsor
Onegevity Health
Industry
Eligibility
18 Years to 79 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistant Starch Blend Gastrointestinal Impact

NCT03983772
View directory record Official record
Conditions
Quality of Life, Health, Subjective
Interventions
RS blend, Placebo
Dietary Supplement · Other
Lead sponsor
Metagenics, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Gig Harbor, Washington
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Jun 27, 2026, 2:22 AM EDT