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ClinicalTrials.gov public records Last synced Oct 1, 2026, 11:08 PM EDT

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Showing 25–48 of 2,842 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stress, Mental Clear all
Completed Not applicable Interventional Results available

Trauma-informed Collaborative Care for Low-income African Americans With PTSD

NCT03591107
View directory record Official record
Conditions
PTSD
Interventions
PTSD Care Management (PCM), Minimally Enhanced Usual Care (MEU)
Other
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 1, 2026, 11:08 PM EDT
Completed No phase listed Observational

Optimizing CAB-LA as PrEP for Women Who Inject Drugs

NCT05799339
View directory record Official record
Conditions
HIV Infections, Opioid Use, Trauma, Psychological
Interventions
Not listed
Lead sponsor
Alexis Roth
Other
Eligibility
18 Years and older · Female only
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 1, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

Digital Intervention for Physical Activity

NCT07130734
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Anxiety, Stress
Interventions
Digital Physical Activity
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
19 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 1, 2026, 11:08 PM EDT
Active, not recruiting Not applicable Interventional

Feasibility of the 5-Step Method in the U.S.

NCT06565429
View directory record Official record
Conditions
Family Members, Relatives, Substance-Related Disorders, Alcohol-Related Disorders, Coping Skills, Stress, Psychological, Stress Physiology
Interventions
5-Step Method Intervention
Behavioral
Lead sponsor
Villanova University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological Outcomes

NCT04510272
View directory record Official record
Conditions
Anxiety, Depression, PTSD
Interventions
Aloud Real-time Reading of ICU Diaries
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Phase 1Phase 2 Interventional

Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)

NCT00992953
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Treatment as Usual, Virtual Reality Exposure with Stimulus Control
Behavioral
Lead sponsor
Office of Naval Research (ONR)
Federal
Eligibility
18 Years to 65 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Camp Pendlton, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2009 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neurobiological Responses in Alcoholism and Early Trauma

NCT04128228
View directory record Official record
Conditions
Alcohol Use Disorder, Early Trauma Complications
Interventions
8-week outpatient treatment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Phase 1 Interventional

A Clinical Trial for Post Traumatic Stress Disorder

NCT00554177
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
Medicane (mifepristone), Placebo
Drug
Lead sponsor
Antonia New
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life

NCT01009112
View directory record Official record
Conditions
Nightmares, Insomnia, Posttraumatic Stress Disorder
Interventions
PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self Help Intervention to Decrease Stress

NCT01242865
View directory record Official record
Conditions
Stress, Psychological
Interventions
Attention and Interpretation Therapy
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 1, 2026, 11:08 PM EDT
Recruiting Phase 2 Interventional

MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder

NCT05837845
View directory record Official record
Conditions
PTSD
Interventions
MDMA, Cognitive Processing Therapy, MDMA-assisted Cognitive Processing Therapy (MDMA-aCPT)
Drug · Behavioral
Lead sponsor
Patricia Suppes
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU

NCT02926677
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

The Impact of Vocational Rehabilitation on Mentally III Veterans

NCT00333801
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Vocational Rehabilitation Program (VRP), Individual Placement and Support (IPS)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 1, 2026, 11:08 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors

NCT05086757
View directory record Official record
Conditions
Traumatic Injury, Technology, Posttraumatic Stress Disorder, Adolescents
Interventions
TRRP, Enhanced Usual Care
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder

NCT01158001
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Depression, Anxiety
Interventions
Prolonged exposure therapy
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2015 · Synced Oct 1, 2026, 11:08 PM EDT
Terminated Phase 1Phase 2 Interventional

Reducing Risk and Trauma-Related Stress in Persons Living With HIV

NCT00186030
View directory record Official record
Conditions
HIV, PTSD
Interventions
HIV Skills-based Prevention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
102 participants
Timeline
2003 – 2004
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 6, 2006 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Stress and Health Interview for Primary Care Patients With Medically Unexplained Symptoms

NCT02151500
View directory record Official record
Conditions
Somatoform Disorders
Interventions
Stress and Health Interview
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Rochester Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 8, 2015 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Trauma Management Therapy for OEF and OIF Combat Veterans

NCT02809326
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Combat Disorders
Interventions
17 week Exposure Therapy Control Arm, Trauma Management Therapy, Intensive 3-Week Trauma Management Therapy
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 31, 2017 · Synced Oct 1, 2026, 11:08 PM EDT
Not yet recruiting Not applicable Interventional

First Responder Safety Training (FiRST)

NCT07478250
View directory record Official record
Conditions
Resilience and Mental Health of First Responders
Interventions
Worker Resilience Training Program, Fire and Medical Safety (FAMS)
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Stony Brook, New York • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 1, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Open Trial of Behavioral Activation and Social Engagement (BASE) for Posttraumatic Stress Disorder (PTSD)

NCT03191760
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Behavioral Activation
Behavioral
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 1, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

The BEAR Program for Women With Trauma Who Have Suicidal Thoughts

NCT07346638
View directory record Official record
Conditions
Interpersonal Trauma, Depression, PTSD, Anxiety, Suicidal Ideations, Sexual Assault
Interventions
BEAR-SI
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 1, 2026, 11:08 PM EDT
Not listed Not applicable Interventional

The Effects of MBSR on Patients With TBI and Chronic Insomnia

NCT03560843
View directory record Official record
Conditions
Chronic Insomnia, TBI (Traumatic Brain Injury)
Interventions
MBSR
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 1, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Using Mobile Technology to Address the Trauma Mental Health Treatment Gap

NCT05374408
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Aim 2: BounceBack Now (BBN) for Trauma Informed Care Deployment, Aim 1 Participant Focus Groups, Aim 1 BHP Focus Groups, Aim 2: BHP, Provider, Staff and Admin Focus Groups, Aim 2 : Participant Focus Group
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 1, 2026, 11:08 PM EDT
Not listed Phase 2Phase 3 Interventional

Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder

NCT05637879
View directory record Official record
Conditions
PTSD
Interventions
Glecaprevir/pibrentasvir, Placebo
Drug · Other
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
19 Years to 70 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 1, 2026, 11:08 PM EDT