Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:50 AM EDT

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Showing 73–96 of 2,842 matching trials from the live ClinicalTrials.gov search.
Conditions
Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression, Post-traumatic Stress Disorder (PTSD)
Interventions
Ketamine, standard general anesthesia
Drug
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Lubbock, Texas
Withdrawn Not applicable Interventional

Big Mind for Veterans With PTSD

NCT02541630
Conditions
PTSD
Interventions
Big Mind
Behavioral
Lead sponsor
VA Salt Lake City Health Care System
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
HIV Infections, AIDS, Opiate Dependence, Post-Traumatic Stress Disorders
Interventions
On-site - buprenorphine/naloxone (Suboxone), Off-site - methadone or no agonist
Drug
Lead sponsor
Ruth M. Rothstein CORE Center
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Better Together: an Online Physician Coaching Program for Medical Trainees

NCT05280964
Conditions
Burnout, Self-compassion, Moral Injury, Impostor Phenomenon
Interventions
Better Together Physician Coaching
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Enrolling by invitation Not applicable Interventional

Testing STAR and TextSTAR: A Randomized Controlled Trial

NCT07630428
Conditions
Sexual Violence, Posttraumatic Stress Disorder (PTSD), Opioid Misuse
Interventions
Skills Training in Active Recovery (STAR) Video, Text Skills Training in Active Recovery (TextSTAR) program
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Louisville, Kentucky • Chapel Hill, North Carolina • Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Family Caregivers of Persons With Dementia

NCT05336344
Conditions
Caregiver Stress Syndrome, Anxiety, Depression
Interventions
ENCODE
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
In Vitro Fertilization, Psychological Stress
Interventions
Phone calls
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Caregiver Burden, Caregiver Burnout, Dementia
Interventions
CarePair
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Stress Disorders, Post-Traumatic, HIV Infections
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
2
States / cities
Akron, Ohio • Cleveland, Ohio
Completed Not applicable Interventional Results available

Physiological Augmentation of Mindfulness Meditation

NCT02754557
Conditions
Post Traumatic Stress Disorder
Interventions
Breath-Focused Meditation, Physiological Feedback
Other · Device
Lead sponsor
Emory University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia
Conditions
HIV Infections, Mild Cognitive Impairment
Interventions
Mindfulness, Usual Care
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Osteochondritis Dissecans Knee, Psychological Stress
Interventions
Surgical Treatment, Nonoperative Treatment
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
11 Years to 19 Years
Enrollment
120 participants
Timeline
2021 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Frisco, Texas
Conditions
PTSD, Alcohol Use Disorder
Interventions
Sertraline, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Stress Disorders, Post-Traumatic
Interventions
Freespira Breathing System
Device
Lead sponsor
Palo Alto Health Sciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Autism, Trauma, Posttraumatic Stress Disorder, Posttraumatic Stress Symptom
Interventions
Written Exposure Therapy (WET) via telehealth
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Laramie, Wyoming
Conditions
Acute Stress Reaction
Interventions
iCOVER, Physical Presence with Reassurance
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Belmont, Massachusetts • Worcester, Massachusetts • Detroit, Michigan + 2 more
Not listed Phase 1 Interventional Accepts healthy volunteers

Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults

NCT05894902
Conditions
Major Depression, Post Traumatic Stress Disorder
Interventions
SM-001
Drug
Lead sponsor
Advanced Integrative Medical Science Institute
Other
Eligibility
25 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Results available

Trauma Informed Guilt Reduction Therapy

NCT02512445
Conditions
Guilt, Shame, Post-traumatic Stress Disorders
Interventions
Trauma Informed Guilt Reduction Therapy, Supportive Care Therapy
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
3
States / cities
San Diego, California • Boston, Massachusetts • Providence, Rhode Island
Conditions
Frequent Trauma-related Nightmares
Interventions
Exposure, Relaxation, and Rescripting Therapy
Behavioral
Lead sponsor
University of Tulsa
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
Tulsa, Oklahoma
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Holistic Health Program for United Methodist Clergy

NCT01564719
Conditions
Obesity, Depression, Diabetes, Hypertension, Hypercholesterolemia
Interventions
Holistic health
Behavioral
Lead sponsor
Duke Clergy Health Initiative
Other
Eligibility
18 Years and older
Enrollment
1,114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Alzheimer Disease, Caregiver Burden
Interventions
AURA_ALZ
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 110 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive Processing Therapy, Cognitive Processing Therapy (CPT) + Memory Support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Stress Disorders, Post-Traumatic, Depression
Interventions
Mindfulness-based stress reduction
Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Conditions
PTSD
Interventions
Experimental, Active Control
Behavioral
Lead sponsor
Thomas Adams
Other
Eligibility
21 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky