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These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:58 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 1,722 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Stress Disorder, Post Traumatic Clear all

Conditions: PTSD, Alcohol Use Disorder
Interventions: Sertraline, Placebo; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 21 Years to 65 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Stress Disorders, Post-Traumatic, Affect, Memory
Interventions: Processing of Positive Memories Technique (PPMT), Supportive Counseling (SC); Behavioral
Lead sponsor: University of North Texas, Denton, TX; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Denton, Texas

Conditions: PTSD, Substance Use Disorders
Interventions: COPEWeb online training, COPE In Person; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 248 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
Interventions: Brief CBT-Based Intervention, Enhanced Treatment as Usual; Behavioral · Other
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 15 Years and older · Female only
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Post Traumatic Stress Disorder
Interventions: TSND-201; Drug
Lead sponsor: Transcend Therapeutics; Industry
Eligibility: Not listed
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 17
States / cities: Little Rock, Arkansas • Los Angeles, California • Montclair, California + 14 more

Conditions: Post Traumatic Stress Disorder
Interventions: Brexpiprazole, Sertraline, Placebo; Drug · Other
Lead sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 591 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Mild Traumatic Brain Injury, Distress-based Psychopathology, Chronic Pain
Interventions: Acceptance and Commitment Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Borderline Personality Disorder, Post-Traumatic Stress Disorders
Interventions: Crisis resolution; Behavioral
Lead sponsor: Laddis, Andreas, M.D.; Individual
Eligibility: 19 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Pocasset, Massachusetts

Conditions: Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
Interventions: Creating Change (CC), Seeking Safety (SS); Behavioral
Lead sponsor: VA Boston Healthcare System; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: PTSD
Interventions: CORT108297, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 69 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Tuscaloosa, Alabama • San Francisco, California

Conditions: PTSD
Interventions: CPT for PTSD; Behavioral
Lead sponsor: VA Salt Lake City Health Care System; Federal
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Post-Traumatic Stress Disorder, Overweight and Obesity, Metabolic Syndrome, Inflammation
Interventions: Mediterranean Diet & Physical Activity, Usual Care; Behavioral
Lead sponsor: Stony Brook University; Other
Eligibility: 40 Years to 65 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Commack, New York

Conditions: Post-Traumatic Stress Disorder, Depression
Interventions: Group Intervention for Interpersonal Trauma, Information only; Behavioral · Other
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Alcohol Problems, Post-Traumatic Stress Disorder
Interventions: Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2028 – 2030
U.S. locations: 1
States / cities: Bedford, Massachusetts

Conditions: Posttraumatic Stress Disorder
Interventions: Motivational Enhancement Therapy, Treatment as Usual; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 163 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: PTSD, Stress
Interventions: Mindfulness Meditation (MfM); Behavioral
Lead sponsor: Corporal Michael J. Crescenz VA Medical Center; Federal
Eligibility: 18 Years to 55 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Anxiety, Depressive Symptoms, Post-traumatic Stress Disorder, Problems Psychosocial
Interventions: Rare Group Problem Management Plus; Behavioral
Lead sponsor: Children's National Research Institute; Other
Eligibility: 18 Years to 99 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Stress Disorders, Post-Traumatic, Alcohol-Related Disorders
Interventions: PC-TIME, PC-TAU; Behavioral
Lead sponsor: Syracuse VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Buffalo, New York • Syracuse, New York

Conditions: Anxiety Disorders, Depression, Post Traumatic Stress Disorder
Interventions: COGENT, Sham Program; Behavioral · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 21 Years to 55 Years
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Diego, California

Conditions: Posttraumatic Stress Disorder
Interventions: Prolonged exposure (PE), PE plus Sertraline; Behavioral · Other
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: Cleveland, Ohio • Seattle, Washington

Conditions: Stress Disorders, Post-Traumatic
Interventions: tcVNS, sham; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: paroxetine, placebo; Drug
Lead sponsor: Foundation for Atlanta Veterans Education and Research, Inc.; Other
Eligibility: 18 Years to 50 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: PTSD, Alcohol Use Disorder, Depression, Anxiety
Interventions: Brief Unified Protocol, Psychoeducation; Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 21 Years and older
Enrollment: 480 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Waco, Texas

Conditions: Posttraumatic Stress Disorder
Interventions: Stepped Care TF-CBT, Standard TF-CBT; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 4 Years to 70 Years
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 6
States / cities: Jacksonville, Florida • Largo, Florida • New Port Richey, Florida + 2 more

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Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems

Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health

COPEWeb Training for Providers

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

An Evaluation of the Long-Term Safety and Efficacy of TSND-201 for the Treatment of PTSD

Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder

One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology

Outcome of Crisis Intervention for Subjects With Borderline Personality Disorder or Post-Traumatic Stress Disorder

Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder

Phase IIa Trial of a Selective Glucocorticoid Receptor Antagonist in the Treatment of Veterans With Posttraumatic Stress Disorder (PTSD) (Seven Study)

Delivery Considerations of Cognitive Processing Therapy for PTSD

Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders

Group Intervention for Interpersonal Trauma

The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans

Efficacy Trial of Stress Check-Up

Use of Mindfulness Meditation With Iraqi/Afghanistan War Veterans

Rare Group Problem Management Plus

Primary Care Treatment Integrating Motivation and Exposure

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

Optimizing Posttraumatic Stress Disorder Treatment: Prolonged Exposure (PE) Versus PE Plus Sertraline

Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder

Neural Correlates of Early Intervention for Posttraumatic Stress Disorder (PTSD)

Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees

Stepped Care for Children After Trauma: Optimizing Treatment