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Showing 577–600 of 1,722 matching trials from the live ClinicalTrials.gov search.
Conditions
Combat Disorders, Post-traumatic Stress Disorder
Interventions
Prolonged Exposure Therapy (PE), Relaxation Training (RT)
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older · Male only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Diego, California
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Oxytocin and Affect Processing in Posttraumatic Stress Disorder

NCT02546570
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Completed No phase listed Observational Accepts healthy volunteers

Longitudinal Survey Analysis in Lymphoma Survivors

NCT01469754
Conditions
Lymphoma, Posttraumatic Stress Disorder, Posttraumatic Growth, Coping, Resilience
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Self-directed Violence, Post-traumatic Stress Disorder (PTSD)
Interventions
Dialectical Behavior Therapy, Dialectical Behavior Therapy Prolonged Exposure protocol, Prolonged Exposure therapy, Suicide risk management
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Minneapolis, Minnesota • Durham, North Carolina • San Antonio, Texas + 1 more
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy, Prolonged Exposure Therapy
Behavioral
Lead sponsor
University of Missouri, St. Louis
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1994
U.S. locations
1
States / cities
St Louis, Missouri
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD

NCT02876172
Conditions
Posttraumatic Stress Disorder
Interventions
MDMA, CBCT, Therapy
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Not listed Not applicable Interventional Accepts healthy volunteers

PFI Hazardous Drinkers With Subclinical PTSD

NCT04836442
Conditions
Hazardous Drinking, Posttraumatic Stress Disorder
Interventions
Alcohol-PTSD-PFI (AP-PFI), Active Comparison Condition (C-PFI)
Other
Lead sponsor
University of Houston
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Not yet recruiting Not applicable Interventional

CBITS-RTM Pilot Study

NCT07682441
Conditions
PTSD - Post Traumatic Stress Disorder, Substance Use
Interventions
Adapted Cognitive Behavioral Intervention for Trauma in Schools (CBITS) with a Racial Trauma Module (RTM)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Active, not recruiting Not applicable Interventional Results available

Circadian Influence on Prolonged Exposure Therapy for PTSD

NCT05453162
Conditions
PTSD
Interventions
Prolonged Exposure Therapy for Posttraumatic Stress Disorder
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Resilient Roots: Supporting Youth and Families

NCT06535516
Conditions
Posttraumatic Stress Disorder
Interventions
Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) augmented with Socialization (S)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
10 Years to 15 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Rochester, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

NightWare and Cardiovascular Health in Women With PTSD

NCT07021014
Conditions
Post Traumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness, Nightmare, Endothelial Dysfunction, Kidney Diseases, Renal Dysfunction, Trauma and Stressor Related Disorders
Interventions
NightWare, Sham NightWare
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
22 Years to 40 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Conditions
Stress Disorders, Post-Traumatic
Interventions
Balovaptan, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 60 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
15
States / cities
Phoenix, Arizona • Bellflower, California • Panorama City, California + 12 more
Conditions
Psychosocial Functioning, Stress Disorders, Post-Traumatic, Depressive Disorder, Major
Interventions
Self-Guided STAIR Coach with Real-Time Assessment, Real-Time Assessment
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Results available

Positive Processes and Transition to Health

NCT04678232
Conditions
Major Depressive Disorder, Post Traumatic Stress Disorder
Interventions
Positive Processes and Transition to Health (PATH)
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Newark, Delaware • Cleveland, Ohio • Seattle, Washington
Conditions
Post Traumatic Stress Disorder, Anxiety Disorders, Panic Disorder, Social Phobia, Phobia
Interventions
Novelty facilitated extinction, Standard Extinction
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Austin, Texas
Conditions
Stress Disorders, Post-Traumatic
Interventions
Paroxetine, Placebo
Drug
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive behavioral therapy (CBT), Brief PTSD treatment
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
5
States / cities
Monmouth Junction, New Jersey • New Brunswick, New Jersey • Newark, New Jersey
Conditions
Brain Injury, Cognition, PTSD, Intervention
Interventions
Goal Management Training plus Attention Training, Brain Health Workshop and National Geographic Movies
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 55 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Xyrem for Treatment Refractory Insomnia Due to PTSD

NCT00330291
Conditions
PTSD, Anxiety, Post Traumatic
Interventions
Xyrem
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Syracuse, New York
Completed Phase 2 Interventional Results available

Phase II Study of BNC210 in PTSD

NCT02933606
Conditions
Post-Traumatic Stress Disorder
Interventions
BNC210, Placebo
Drug
Lead sponsor
Bionomics Limited
Industry
Eligibility
18 Years to 70 Years
Enrollment
193 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
20
States / cities
Oceanside, California • Rancho Mirage, California • Redlands, California + 17 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Network Dysregulation Among Individuals With Comorbid Tinnitus and PTSD

NCT03702166
Conditions
Stress Disorders, Post-Traumatic, Tinnitus
Interventions
Cognitive Processing Therapy (CPT)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Neuropathic Pain, PTSD
Interventions
Ketamine, Magnesium sulfate, Ketamine + Magnesium sulfate
Drug
Lead sponsor
Margaux M. Salas, PhD
Federal
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Anxiety, Acute Stress Disorder, Posttraumatic Stress Disorder, Depression
Interventions
Brief Cognitive Behavioral Treatment
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
U.S. locations
1
States / cities
Stanford, California
Conditions
Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder, Fear of Falling
Interventions
Exposure-based Cognitive Behavioral Therapy, Relaxation Training
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York