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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:59 AM EDT

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Showing 313–336 of 1,715 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stress Disorders, Post-Traumatic Clear all
Recruiting Phase 2Phase 3 Interventional

Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

NCT07570654
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms, PTSD, Post Traumatic Stress Disorder
Interventions
COMP360 psilocybin
Drug
Lead sponsor
COMPASS Pathways
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
7
States / cities
Miami, Florida • Orlando, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blast Exposed Veterans With Auditory Complaints

NCT02122458
View directory record Official record
Conditions
Hearing Impairment, Hearing Aid Fitting
Interventions
mild-gain hearing aids with high-frequency emphasis over 6-months
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 50 Years
Enrollment
363 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
3
States / cities
Portland, Oregon • Pittsburgh, Pennsylvania • Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional

The Efficacy of 90-Minute Versus 60-Minute Sessions of Prolonged Exposure for PTSD

NCT02720497
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Combat Disorder
Interventions
60-minute Prolonged Exposure Therapy, 90-minute Prolonged Exposure Therapy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2021 · Synced Oct 21, 2026, 6:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD

NCT05895318
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Albany Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness of Two Treatments for Veterans With PTSD

NCT02586064
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Interpersonal Therapy for PTSD, Prolonged Exposure
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
New Orleans, Louisiana • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

A Novel Posttraumatic Stress Disorder Treatment for Veterans With Moral Injury

NCT03764033
View directory record Official record
Conditions
Moral Injury
Interventions
Impact of Killing (IOK), Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 82 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
San Francisco, California • The Bronx, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional

Breathwork Intervention for Posttraumatic Stress

NCT07129278
View directory record Official record
Conditions
PTSD
Interventions
Breathwork
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Branford, Connecticut • Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Completed No phase listed Observational Results available

Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic

NCT04385238
View directory record Official record
Conditions
COVID-19, Pregnancy Complications, Mental Health Wellness 1, Anxiety, Depression, Ptsd, Coronavirus
Interventions
This is an online survey with no intervention.
Other
Lead sponsor
Pregistry
Industry
Eligibility
18 Years and older · Female only
Enrollment
6,894 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2021 · Synced Oct 21, 2026, 6:59 AM EDT
Recruiting Phase 3 Interventional

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

NCT07226232
View directory record Official record
Conditions
Major Depression
Interventions
Psilocybin
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
5
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Portland, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Resettled Refugee Families for Healing

NCT06176638
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Antisocial Personality Disorder, Anxiety, Aggressive Behavior
Interventions
RRF4H Combination Intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 17 Years
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts

NCT03603717
View directory record Official record
Conditions
Insomnia, Suicidal Ideation
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Buffalo, New York • Canandaigua, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

The Effectiveness of rTMS in Depressed VA Patients

NCT01191333
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
rTMS, Sham Device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
9
States / cities
Palo Alto, California • San Francisco, California • Cincinnati, Ohio + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional

Telephone Care as a Substitute for Routine Psychiatric Medication

NCT00105885
View directory record Official record
Conditions
Major Depression, Posttraumatic Stress Disorders, Anxiety Disorders
Interventions
telephone care
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 10, 2014 · Synced Oct 21, 2026, 6:59 AM EDT
Not listed Not applicable Interventional

Decision Aid in Veterans With Posttraumatic Stress Disorder

NCT00908440
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Decision Aid
Behavioral
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated May 25, 2009 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional

Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD)

NCT05536908
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Residential Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Active, not recruiting Not applicable Interventional

Adaption of the STAIR-NT Trauma Intervention for Polysubstance Populations

NCT06307340
View directory record Official record
Conditions
Polysubstance Abuse, Posttraumatic Stress Disorder
Interventions
Skills Training in Affective and Interpersonal Regulation with Narrative Therapy (STAIR-NT), Treatment as Usual
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Tallahassee, Florida • Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Not listed Not applicable Interventional

Narrative Exposure Based Intervention For Post-Traumatic Stress Disorder

NCT03229525
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Trauma Related Expressive Writing, Neutral Expressive Writing
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 13, 2019 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Phase 2 Interventional Results available

Ganaxolone in Posttraumatic Stress Disorder (PTSD)

NCT01339689
View directory record Official record
Conditions
PTSD
Interventions
Ganaxolone, Placebo
Drug
Lead sponsor
Marinus Pharmaceuticals
Industry
Eligibility
18 Years to 55 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
8
States / cities
San Diego, California • Washington D.C., District of Columbia • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2022 · Synced Oct 21, 2026, 6:59 AM EDT
Suspended Phase 2 Interventional Accepts healthy volunteers

Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant

NCT05948540
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Intervention C Daridorexant, Intervention C Placebo
Drug
Lead sponsor
Global Coalition for Adaptive Research
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
9
States / cities
Miami, Florida • Atlanta, Georgia • Tripler AMC, Hawaii + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttraumatic Stress Disorder

NCT06249386
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder
Interventions
Behavioral Activation (BA), Relapse Prevention (RP)
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Tobacco Cessation for Veterans With Post Traumatic Stress Disorder (PTSD)

NCT00908882
View directory record Official record
Conditions
Tobacco Use Cessation, Post Traumatic Stress Disorders
Interventions
Motivation Interviewing Counseling
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 16, 2015 · Synced Oct 21, 2026, 6:59 AM EDT
Recruiting Not applicable Interventional

Early General Anesthesia to Limit Experiences of Trauma During Cesarean Section-Pilot Study

NCT07334418
View directory record Official record
Conditions
Cesarean Section, Delivery; Trauma
Interventions
General anesthetic, Intravenous anesthetic
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Meditation Interventions for Treatment of PTSD in Veterans

NCT01548742
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Mindfulness-Based Stress Reduction (MBSR), Present-Centered Group Therapy (PCGT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 10, 2015 · Synced Oct 21, 2026, 6:59 AM EDT
Completed Phase 3 Interventional Results available

Stepped Preventive Care to Reduce the Impact of Acute Pediatric Injury

NCT00451282
View directory record Official record
Conditions
Stress Disorders, Posttraumatic
Interventions
stepped preventive care
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 17 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2015 · Synced Oct 21, 2026, 6:59 AM EDT