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ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:38 PM EDT

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Showing 361–384 of 1,716 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stress Disorders, Post-Traumatic Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Web and Shared Decision Making for Reserve/National Guard Women's PTSD Care

NCT01710306
View directory record Official record
Conditions
PTSD
Interventions
Nurse Care Manager (NCM)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years · Female only
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional

Improving Sleep to Reduce Risk for Substance Use Disorder

NCT03226132
View directory record Official record
Conditions
Substance Use Disorders, Insomnia, Posttraumatic Stress Disorder
Interventions
Brief Behavioral Therapy for Insomnia, Repeated Contact
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Oct 21, 2026, 3:38 PM EDT
Active, not recruiting Not applicable Interventional

The Feasibility and Examination of the Effects of Floatation-based REST on a Community Sample With PTSD

NCT04368689
View directory record Official record
Conditions
Post-Traumatic Stress Disorders
Interventions
Floatation-based reduced environmental stimulation therapy
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 21, 2026, 3:38 PM EDT
Recruiting Not applicable Interventional

Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples

NCT06047691
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Abbreviated, Intensive, Multi-Couple Group Cognitive-Behavioral Conjoint Therapy for PTSD, Prevention and Relationship Education Program
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional Results available

Peer Social Support During In Vivo Exposure for PTSD

NCT03485391
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Anxiety Disorders, Mental Disorder, Traumatic Disorder
Interventions
Prolonged Exposure
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2024 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional

Accelerated Resolution Therapy (ART) for Psychological Trauma

NCT01559688
View directory record Official record
Conditions
Psychological Trauma, PTSD
Interventions
Accelerated Resolution Therapy (ART), Waitlist
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 21, 2026, 3:38 PM EDT
Not yet recruiting Not applicable Interventional

Cognitive Training for Functioning in PTSD

NCT07693686
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
COGENT (Cognitive ENhancement Training), ST (Sham Training)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 21, 2026, 3:38 PM EDT
Not yet recruiting Not applicable Interventional

Self-Compassion, Health, and Empowerment

NCT07733531
View directory record Official record
Conditions
Intimate Partner Violence (IPV), Depression and/or Anxiety Symptoms, PTSD - Post Traumatic Stress Disorder
Interventions
The Self-Compassion, Health, and Empowerment (SHE) Intervention, Health and Nutrition Program
Behavioral
Lead sponsor
Yang Li
Other
Eligibility
18 Years and older · Female only
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASS

NCT01816061
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Traumatic Stress Disorder
Interventions
Experimental - COMPASS, Control - COMPASS
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 55 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Oct 21, 2026, 3:38 PM EDT
Recruiting Not applicable Interventional

Behavioral Health Collaborative Care Model in an ICU Recovery Clinic

NCT07372586
View directory record Official record
Conditions
PICS, Anxiety, Depression - Major Depressive Disorder, Post-Traumatic Stress, PTSD, Critical Illness Recovery, Critical Illness, Collaborative Care, Behavioral Health Concerns
Interventions
Behavioral Health Collaborative Care Model
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Trial of Narrative Exposure Therapy (NET) for Posttraumatic Stress Disorder (PTSD) During Pregnancy

NCT04525469
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Narrative Exposure Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 22, 2022 · Synced Oct 21, 2026, 3:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Moral Injury Symptom Scale/Moral Injury Outcome Scale

NCT04261751
View directory record Official record
Conditions
Moral Injury, Anxiety, Depression, Burn-Out
Interventions
Clinician Questionnaire
Other
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
483 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 21, 2026, 3:38 PM EDT
Terminated Phase 4 Interventional

An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder

NCT05254405
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Brexanolone Injection [Zulresso]
Drug
Lead sponsor
Donald Jeffrey Newport
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional

Treatment for Psychogenic Nonepileptic Seizures and Post-traumatic Stress Disorder Using Prolonged Exposure Therapy (PE) or Psychoeducation for PNES

NCT07344766
View directory record Official record
Conditions
Psychogenic Nonepileptic Seizures (PNESs), Post Traumatic Stress Disorder PTSD
Interventions
imaginal and in vivo exposure, psychoeducation for psychogenic nonepileptic seizures
Behavioral
Lead sponsor
Northeast Regional Epilepsy Group
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Nicotine Patch Pretreatment for Smoking Cessation in PTSD

NCT00625131
View directory record Official record
Conditions
Stress Disorders, Posttraumatic, Tobacco Use Disorder
Interventions
Nicotine, Cognitive Behavioral Therapy for Smoking Cessation, Bupropion Sustained Release (SR), Placebo patch
Drug · Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 20, 2014 · Synced Oct 21, 2026, 3:38 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Xyrem for Treatment Refractory Insomnia Due to PTSD

NCT00330291
View directory record Official record
Conditions
PTSD, Anxiety, Post Traumatic
Interventions
Xyrem
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Sep 7, 2012 · Synced Oct 21, 2026, 3:38 PM EDT
Withdrawn Not applicable Interventional

Chilipad for Sleep and Symptoms of PTSD

NCT03924297
View directory record Official record
Conditions
PTSD
Interventions
chilipad
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 3, 2020 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Phase 3 Interventional

Fluoxetine vs EMDR to Treat Post-Traumatic Stress Disorder (PTSD)

NCT00000379
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Fluoxetine, EMDR
Drug · Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2003
U.S. locations
1
States / cities
Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2014 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Phase 3 Interventional Results available

Naltrexone & SSRI in Alcoholics With Depression/PTSD

NCT00338962
View directory record Official record
Conditions
Alcoholism, Depression, PTSD
Interventions
paroxetine, desipramine, Naltrexone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 75 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 5, 2016 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional Results available

Telephone Case Monitoring (TCM) for Veterans With Post-Traumatic Stress Disorder (PTSD)

NCT00288860
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Telephone monitoring, Treatment-As-Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
837 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
5
States / cities
No. Little Rock, Arkansas • Battle Creek, Michigan • Buffalo, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Oct 21, 2026, 3:38 PM EDT
Completed Not applicable Interventional

Impact of Community-Based Biofeedback Program on Drug Use and Mental Health Among People Experiencing Homelessness

NCT05897580
View directory record Official record
Conditions
Heart Rate Variability
Interventions
Heart Rate Variability - Biofeedback (HRV-BF), Health Promotion (HP)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2023 · Synced Oct 21, 2026, 3:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Effects of Stress in Pregnancy

NCT00525226
View directory record Official record
Conditions
Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,431 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Oct 21, 2026, 3:38 PM EDT
Terminated Phase 2 Interventional Results available

Nitrous Oxide for PTSD

NCT04378426
View directory record Official record
Conditions
PTSD
Interventions
Nitrous Oxide, Midazolam, Nitrogen, Oxygen, Saline
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2023 · Synced Oct 21, 2026, 3:38 PM EDT
Recruiting Phase 2 Interventional

Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy

NCT07214415
View directory record Official record
Conditions
TBI Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Post Concussive Syndrome
Interventions
Hyperbaric Oxygen Therapy
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 21, 2026, 3:38 PM EDT