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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Stress Disorders, Post-Traumatic Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Telephone-based Care for OEF/OIF Veterans With PTSD

NCT00680524
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Phone-based outreach
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional

Group vs. Individual Cognitive Processing Therapy for Combat-related PTSD

NCT02173561
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Group Cognitive Processing Therapy-Cognitive Only, Individual Cognitive Processing Therapy-Cognitive Only
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2017 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Reducing Alcohol Use & Post-traumatic Stress Disorder (PTSD) With Cognitive Restructuring & Experiential Acceptance

NCT00760994
View directory record Official record
Conditions
Alcoholism, Stress Disorders, Post-Traumatic
Interventions
Experiential acceptance, Cognitive restructuring, No-intervention control: Nutrition information
Behavioral · Other
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 9, 2020 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions

NCT04245423
View directory record Official record
Conditions
Opioid-use Disorder, Mental Health Conditions
Interventions
Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
567 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional

Guided Imagery for Military Sexual Trauma-Related Posttraumatic Stress Disorder (PTSD)

NCT00635635
View directory record Official record
Conditions
Stress Disorder, Post Traumatic, Military Sexual Trauma
Interventions
Guided Imagery Audio, Music Audio
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2010 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Attentional Bias Modification to Address Trauma Symptoms

NCT02615717
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Attention Bias Modification
Behavioral
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 70 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Jul 22, 2026, 3:59 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD

NCT04961190
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR
Behavioral · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
7
States / cities
Birmingham, Alabama • Menlo Park, California • San Diego, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional

Integrated PTSD and Smoking Treatment

NCT01988935
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Prolonged Exposure, Smoking Cessation
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Phase 4 Interventional

Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder

NCT00025740
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
clonazepam and paroxetine
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 22, 2026, 3:59 PM EDT
Terminated Not applicable Interventional

Initial Intervention Efficacy for an Online PTSD Intervention for Pregnant Women

NCT04264520
View directory record Official record
Conditions
Perinatal Problems, Post Traumatic Stress Disorder, Post Partum Depression
Interventions
PTSD Psychoeducation + Skills Intervention
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Jul 22, 2026, 3:59 PM EDT
Terminated No phase listed Observational

Hyperbaric Oxygen Therapy in Chronic Traumatic Brain Injury or Post-Traumatic Stress Disorder

NCT01105962
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
International Hyperbaric Medical Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
10
States / cities
San Francisco, California • Boulder, Colorado • Delray Beach, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2016 · Synced Jul 22, 2026, 3:59 PM EDT
Completed No phase listed Observational

The Effects of Home-Based Telemental Health for Rural Veterans With PTSD

NCT02295410
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
CPT
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Phase 2Phase 3 Interventional

Levetiracetam in Post-Traumatic Stress Disorder

NCT00413296
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
levetiracetam, Placebo, Levetriracetam
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Phase 2 Interventional Results available

Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine

NCT01031979
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Yohimbine, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 45 Years · Male only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Interventions for Parent Caregivers of Injured Military/Veteran Personnel

NCT03309046
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Brain Injuries, Traumatic
Interventions
REACH Individual Session, Education Webinar
Other
Lead sponsor
Memphis VA Medical Center
Federal
Eligibility
Not listed
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 22, 2023 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Group CBT for Aggression in Veterans

NCT02233517
View directory record Official record
Conditions
Aggression, Anger, Posttraumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Efficacy of a Digital Mental Health Intervention for Teen Wildfire Survivors

NCT03868761
View directory record Official record
Conditions
Disaster, PTSD, Adolescent Behavior, Trauma, Anxiety, Stress
Interventions
Sonoma Rises
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 17 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Jul 22, 2026, 3:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Preventing Childbirth-Related PTSD With Expressive Writing

NCT05662423
View directory record Official record
Conditions
PTSD (Childbirth-Related)
Interventions
Expressive Writing about Childbirth, Neutral Writing
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Propranolol on Preventing Posttraumatic Stress Disorder

NCT00158262
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)

NCT01466127
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Enhanced Problem-Solving Training

NCT03759223
View directory record Official record
Conditions
Brain Concussion
Interventions
Enhanced Problem-Solving Training (E-PST), Healthy Living Messages (HLM), Enhanced Problem-Solving Training (E-PST) (non-randomized)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Jul 22, 2026, 3:59 PM EDT
Withdrawn Not applicable Interventional

Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD

NCT04543513
View directory record Official record
Conditions
PTSD, Cognitive Function
Interventions
Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
Other
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional

PTSD Treatment for Incarcerated Men and Women: WPP

NCT05432817
View directory record Official record
Conditions
PTSD
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 22, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Quantifying the Efficacy and Role of Service Dogs for Military Veterans With PTSD

NCT03245814
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Service Dog
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Jul 22, 2026, 3:59 PM EDT