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ClinicalTrials.gov public records Last synced Oct 24, 2026, 10:27 PM EDT

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Showing 913–936 of 1,718 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stress Disorders, Post-Traumatic Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents

NCT03737383
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Use Disorders
Interventions
Narrative Exposure Therapy
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
16 Years to 25 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Not applicable Interventional

Evaluating the Feasibility of RESCUE: An Adjunctive HAI-Based Intervention for Veterans With PTSD

NCT03504722
View directory record Official record
Conditions
PTSD
Interventions
RESCUE, Prolonged Exposure
Behavioral
Lead sponsor
Charleston Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 24, 2026, 10:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Morning Bright Light to Improve Sleep Quality in Veterans

NCT03578003
View directory record Official record
Conditions
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
Interventions
Morning Bright Light Therapy
Other
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Portand, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Trial of Narrative Exposure Therapy (NET) for Posttraumatic Stress Disorder (PTSD) During Pregnancy

NCT04525469
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Narrative Exposure Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 22, 2022 · Synced Oct 24, 2026, 10:27 PM EDT
Completed No phase listed Observational

Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD

NCT02102802
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Midomafetamine, Therapy
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Oct 24, 2026, 10:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Advancing Skills Through Consultation, Education, and Novel Technologies

NCT07707102
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Live workshop, AI-enhanced Web-based training, Consultation video calls, TherapyTrainer
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Phase 1 Interventional

Mindfulness Meditation Format Pilot Study

NCT01581983
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Internet Mindfulness Meditation, Individual Mindfulness Meditation
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 13, 2015 · Synced Oct 24, 2026, 10:27 PM EDT
Active, not recruiting No phase listed Observational

Neuropsychological and Mental Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study

NCT00748995
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
817 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
4
States / cities
West Haven, Connecticut • Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 24, 2026, 10:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Post-Traumatic Stress Disorder (PTSD) Symptom Study

NCT00018798
View directory record Official record
Conditions
PTSD
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Male only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 24, 2026, 10:27 PM EDT
Not listed Not applicable Interventional

Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders

NCT05138198
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Overweight and Obesity, Metabolic Syndrome, Inflammation
Interventions
Mediterranean Diet & Physical Activity, Usual Care
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
40 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Commack, New York
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Not applicable Interventional Results available

Study Testing if Fast or Slow rTMS is Better for the Treatment of Posttraumatic Stress Disorder (PTSD)

NCT02158663
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
James A. Haley Veterans Administration Hospital
Federal
Eligibility
18 Years to 50 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Not applicable Interventional

Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD

NCT02290847
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Cognitive Processing Therapy (cognitive only version; CPT-C)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 24, 2026, 10:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

National Guard Outreach and Linkage to Treatment

NCT01020981
View directory record Official record
Conditions
PTSD, Depression, Reintegration, Veterans Health
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 24, 2026, 10:27 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder

NCT00391430
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Sertraline, Cognitive behavioral therapy (CBT)
Drug · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 55 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Phase 2Phase 3 Interventional

Paroxetine-CR to Treat Post-Traumatic Stress Disorder (PTSD) Symptomatic After Initial Exposure Therapy

NCT00215163
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive-behavioral therapy and paroxetine-CR
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
4
States / cities
San Diego, California • Boston, Massachusetts • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 30, 2013 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Interpersonal Treatment Program to Prevent Depression and Post-Traumatic Stress Disorder in Low-Income Pregnant Women With Partner Abuse

NCT00602732
View directory record Official record
Conditions
Depression, Postpartum, Depression
Interventions
The Reach Out for a Safe Environment (ROSE) program, Enhanced care as usual (ECU)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 28, 2014 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Not applicable Interventional

Trial of a Novel Cognitive-Behavioral Treatment for Posttraumatic Stress and Substance Dependence

NCT02461732
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Dependence
Interventions
Treatment for Integrated Posttraumatic Stress and Substance Use (TIPSS), Cognitive-Behavioral Therapy for Substance Dependence
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Tailored Intervention for Behavioral Sequelae of PTSD in Veterans

NCT01510834
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Smoking, Anxiety, Depression
Interventions
Multibehavioral, Computerized Tailored Intervention STR2IVE
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
3
States / cities
Honolulu, Hawaii • Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Oct 24, 2026, 10:27 PM EDT
Recruiting Phase 2Phase 3 Interventional

Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

NCT07570654
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms, PTSD, Post Traumatic Stress Disorder
Interventions
COMP360 psilocybin
Drug
Lead sponsor
COMPASS Pathways
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
9
States / cities
Tucson, Arizona • Miami, Florida • Orlando, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Not applicable Interventional Results available

Primary Care Brief Mindfulness Training for Veterans With PTSD

NCT03352011
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Primary Care Brief Mindfulness Training, PTSD Psychoeducational Class
Behavioral
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 24, 2026, 10:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Nutrition for Trauma Community Survey

NCT06864637
View directory record Official record
Conditions
Psychological Trauma, Historical, Nutrition, PTSD - Post Traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
True Paleo Inc.
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 24, 2026, 10:27 PM EDT
Recruiting Not applicable Interventional

Positive Processes and Transition to Health (PATH)

NCT06093906
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions
Positive Processes and Transition to Health, Progressive Muscle Relaxation
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Newark, Delaware • Cleveland, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 24, 2026, 10:27 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat

NCT06371404
View directory record Official record
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
Bavarostat
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2031
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 24, 2026, 10:27 PM EDT
Completed Phase 2 Interventional Results available

Evaluation of GSK561679 in Women With Post-Traumatic Stress Disorder

NCT01018992
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
GSK561679, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
4
States / cities
San Francisco, California • Atlanta, Georgia • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Oct 24, 2026, 10:27 PM EDT