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ClinicalTrials.gov public records Last synced Oct 25, 2026, 9:42 AM EDT

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Showing 1081–1104 of 1,718 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stress Disorders, Post-Traumatic Clear all
Completed Not applicable Interventional

Effects of Antagonistic Actions in Response to Trauma Exposure

NCT04617769
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Psychoeducation, Exposure
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 60 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Inflammation and Threat Sensitivity in PTSD

NCT03048929
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Typhoid Vi Polysaccharide Vaccine, Placebo
Biological
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 25, 2026, 9:42 AM EDT
Terminated Phase 4 Interventional Results available

Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD)

NCT01555554
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Propranolol Hydrochloride, Placebo
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Early Abuse on Adult Intimate Relationships

NCT01803802
View directory record Official record
Conditions
Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder, Female Orgasmic Disorder, Major Depressive Disorder, Post-traumatic Stress Disorder
Interventions
Expressive writing
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 25, 2026, 9:42 AM EDT
Not listed Not applicable Interventional

Addressing Traumatic Stress Symptoms in Children

NCT03334942
View directory record Official record
Conditions
Violence, Non-accidental, Posttraumatic Stress Disorder, Parent-Child Relations, Assault, Youth
Interventions
Child and Family Traumatic Stress Intervention
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Safety & Efficacy Study Using Topiramate in Posttraumatic Stress Disorder

NCT00204386
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Topiramate
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 30, 2007 · Synced Oct 25, 2026, 9:42 AM EDT
Completed No phase listed Observational

Brain Indices of Risk for Posttraumatic Stress Disorder (PTSD) After Mild Traumatic Brain Injury (mTBI)

NCT01625962
View directory record Official record
Conditions
PTSD
Interventions
Not listed
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 50 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2018 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Emotional Working Memory Training for Veterans With PTSD Symptoms

NCT02766296
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Active Emotional Working Memory Training, Control Working Memory Training
Behavioral
Lead sponsor
Milwaukee VA Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 21, 2018 · Synced Oct 25, 2026, 9:42 AM EDT
Recruiting Not applicable Interventional

Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD

NCT06288711
View directory record Official record
Conditions
Opioid Use Disorder, Posttraumatic Stress Disorder
Interventions
Prolonged exposure therapy, Financial incentives, Treatment as usual
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stepped Care for Children After Trauma: Optimizing Treatment

NCT02537678
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Stepped Care TF-CBT, Standard TF-CBT
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
4 Years to 70 Years
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
6
States / cities
Jacksonville, Florida • Largo, Florida • New Port Richey, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bounce Back Now: A Low-Cost Intervention to Facilitate Post-Disaster Recovery

NCT03403738
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Bounce Back Now, enhanced usual care
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
1,357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional Results available

IT Enhanced Peer Integrated Collaborative Care for US Trauma Care Systems

NCT03569878
View directory record Official record
Conditions
PTSD, Physical Injury
Interventions
Peer-Integrated Multidisciplinary Collaborative Care, Trauma surgery team notification
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 26, 2024 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Intervention for Intrusive Negative Thinking

NCT02394704
View directory record Official record
Conditions
Intrusive Negative Thinking
Interventions
Sensory attention training
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Oct 25, 2026, 9:42 AM EDT
Not listed Early Phase 1 Interventional

Responsive Neurostimulation for Post-Traumatic Stress Disorder

NCT04152993
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
NeuroPace® RNS® System
Device
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
25 Years to 60 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Oct 25, 2026, 9:42 AM EDT
Active, not recruiting Phase 3 Interventional

MDMA-assisted Massed Prolonged Exposure for PTSD

NCT06117306
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
3,4 Methylenedioxymethamphetamine, Prolonged Exposure
Drug · Behavioral
Lead sponsor
Healing Breakthrough
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Mobile Acoustic Startle Reflex-monitoring System (MARS)

NCT04113850
View directory record Official record
Conditions
PTSD
Interventions
Mobile Acoustic startle Reflex monitoring System (MARS)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 27, 2021 · Synced Oct 25, 2026, 9:42 AM EDT
Not yet recruiting Not applicable Interventional

Written Exposure in Substance Treatment (WEST 3.0): Randomized Controlled Trial

NCT07782268
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD)
Interventions
Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional

Treatment of Depression in Patients With PTSD

NCT00013091
View directory record Official record
Conditions
PTSD, Depression
Interventions
Self-management therapy; Psychoeducational group therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2002
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 25, 2026, 9:42 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Computational Assessment of GABA Receptor Modulation in PTSD

NCT06852469
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Lorazepam 1 mg tablet, Placebo tablet
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 25, 2026, 9:42 AM EDT
Recruiting Phase 2 Interventional

Suvorexant for Treatment of AUD and PTSD

NCT06679062
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD), Insomnia
Interventions
Suvorexant, Placebo
Drug · Other
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
21 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional Results available

Yoga and Physical Activity for Veterans

NCT03509909
View directory record Official record
Conditions
PTSD
Interventions
Hatha yoga, Supportive physical activity
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 25, 2026, 9:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wearable Emotion Prosthetics for Post Traumatic Stress Disorder

NCT03529981
View directory record Official record
Conditions
Health Behavior
Interventions
Tuned Vibroacoustic Stimulation (TVS), no active intervention
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 58 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 25, 2026, 9:42 AM EDT
Not listed No phase listed Observational

Advanced MRI In Acute Military TBI

NCT01313130
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 25, 2026, 9:42 AM EDT
Recruiting Phase 1Phase 2 Interventional

Mitigating PTSD-CUD After Sexual Assault

NCT05989841
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Cannabis Use Disorder
Interventions
RISE Guide, Relaxation Control
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
6
States / cities
Minneapolis, Minnesota • Las Vegas, Nevada • Chapel Hill, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 25, 2026, 9:42 AM EDT