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Showing 1–24 of 1,902 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Stress Disorders, Traumatic Clear all
Completed Not applicable Interventional Results available

Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders

NCT01338506
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug Dependence
Interventions
Concurrent Treatment with Prolonged Exposure (COPE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Not applicable Interventional

Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD)

NCT05536908
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Residential Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Results available

Pimavanserin for Insomnia In Veterans With Posttraumatic Stress Disorder

NCT04188392
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Insomnia
Interventions
Pimavanserin
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Sep 10, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Using Mobile Technology to Address the Trauma Mental Health Treatment Gap

NCT05374408
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Aim 2: BounceBack Now (BBN) for Trauma Informed Care Deployment, Aim 1 Participant Focus Groups, Aim 1 BHP Focus Groups, Aim 2: BHP, Provider, Staff and Admin Focus Groups, Aim 2 : Participant Focus Group
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 10, 2026, 4:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Ketone Supplementation in Individuals With PTSD

NCT04083352
View directory record Official record
Conditions
PTSD, Ketosis
Interventions
Pruvit Ketomax Ketone Salt, Placebo
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Not applicable Interventional

Restoring Emotional, Sexual, and Physical Empowerment Through CBT & Trauma-sensitive Care: A Chronic Pelvic Pain Intervention

NCT02588885
View directory record Official record
Conditions
Pelvic Pain, Stress Disorders, Traumatic
Interventions
Trauma-sensitive Care
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Sep 10, 2026, 4:41 PM EDT
Not listed No phase listed Observational

Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort

NCT05855876
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
subanesthetic ketamine infusions and bilateral cervical sympathetic blocks
Procedure
Lead sponsor
Stella Center
Other
Eligibility
40 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Westmont, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 16, 2023 · Synced Sep 10, 2026, 4:41 PM EDT
Recruiting Not applicable Interventional

Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD

NCT07069517
View directory record Official record
Conditions
Insomnia, PTSD - Post Traumatic Stress Disorder, Nightmares
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Written Exposure Therapy (WET), Sleep Hygiene
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Kileen, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

EEG Biofeedback Therapy as an Adjunct Treatment for PTSD

NCT01591408
View directory record Official record
Conditions
PTSD, Anxiety, Trauma, Sleep Disorders
Interventions
EEG biofeedback
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 40 Years · Male only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Sep 10, 2026, 4:41 PM EDT
Recruiting No phase listed Observational

NYSCF Scientific Discovery Biobank

NCT06203106
View directory record Official record
Conditions
ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Batten Disease, Corticobasal Degeneration, Dementia, Frontotemporal Dementia, Huntington Disease, Lewy Body Disease, Multiple Sclerosis, Multiple System Atrophy, Parkinson Disease, Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, INAD, Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Macular Degeneration, Ovarian Cancer, Cervical Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer, PTSD, Post Traumatic Stress Disorder
Interventions
Biological Sample Collection
Other
Lead sponsor
New York Stem Cell Foundation Research Institute
Other
Eligibility
30 Days and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2045
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Sep 10, 2026, 4:41 PM EDT
Active, not recruiting Not applicable Interventional

Treatments in Women Veterans With Insomnia and PTSD

NCT05683132
View directory record Official record
Conditions
Insomnia, PTSD, Women Veterans
Interventions
Trauma-Informed CBT-I, PTSD Psychoeducation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 10, 2026, 4:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Approach-Avoidance and Alcohol Challenge Study in PTSD

NCT06002633
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Alcohol Drinking
Interventions
Alcohol, Placebo
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
21 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 10, 2026, 4:41 PM EDT
Terminated Phase 2 Interventional

The Use of Propranolol to Block Memory Reconsolidation in PTSD

NCT00611871
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Not applicable Interventional

Veterans Nature Therapy (Vet Hike)

NCT03997344
View directory record Official record
Conditions
Posttraumatic Stress Disorders
Interventions
Group nature hikes, Group urban hikes
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 13, 2021 · Synced Sep 10, 2026, 4:41 PM EDT
Recruiting Not applicable Interventional

Behavioral Health Collaborative Care Model in an ICU Recovery Clinic

NCT07372586
View directory record Official record
Conditions
PICS, Anxiety, Depression - Major Depressive Disorder, Post-Traumatic Stress, PTSD, Critical Illness Recovery, Critical Illness, Collaborative Care, Behavioral Health Concerns
Interventions
Behavioral Health Collaborative Care Model
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Not applicable Interventional

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions

NCT04245423
View directory record Official record
Conditions
Opioid-use Disorder, Mental Health Conditions
Interventions
Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
567 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 10, 2026, 4:41 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Neural Correlates of Cognitive Rehabilitation in Post-Traumatic Stress Disorder (PTSD)

NCT00928941
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
cognitive training, video game
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Sep 10, 2026, 4:41 PM EDT
Terminated No phase listed Observational

Hyperbaric Oxygen Therapy in Chronic Traumatic Brain Injury or Post-Traumatic Stress Disorder

NCT01105962
View directory record Official record
Conditions
Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
International Hyperbaric Medical Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
10
States / cities
San Francisco, California • Boulder, Colorado • Delray Beach, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2016 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Results available

Sequenced Treatment Effectiveness for Posttraumatic Stress

NCT04597190
View directory record Official record
Conditions
PTSD
Interventions
Selective serotonin reuptake inhibitor, Serotonin-norepinephrine reuptake inhibitor, Written Exposure Therapy
Drug · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
15
States / cities
North Little Rock, Arkansas • West Memphis, Arkansas • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 10, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study

NCT01407146
View directory record Official record
Conditions
Acute Myocardial Infarction, Heart Attack, Acute Coronary Syndrome, Unstable Angina
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
2,381 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Phase 1 Interventional Results available

Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress Disorder

NCT00946322
View directory record Official record
Conditions
Alcohol-related Disorders, Post-traumatic Stress Disorder
Interventions
Couple-Based Treatment for Alcohol Use Disorders and PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Sep 10, 2026, 4:41 PM EDT
Terminated Phase 2 Interventional

A Clinical Trial of PRAX-114 in Participants With Post-Traumatic Stress Disorder

NCT05260541
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Post Traumatic Stress Disorder, Stress Disorder, Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders, Mental Disorder
Interventions
60 mg PRAX-114 or 40 mg PRAX-114, Placebo, 40 mg PRAX-114
Drug
Lead sponsor
Praxis Precision Medicines
Industry
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
17
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Rogers, Arkansas + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2022 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals

NCT05520190
View directory record Official record
Conditions
Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety, Insomnia, Post Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Sep 10, 2026, 4:41 PM EDT
Completed Not applicable Interventional Results available

A Controlled Trial of Losartan in Posttraumatic Stress Disorder

NCT02709018
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
losartan, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
6
States / cities
La Jolla, California • Washington D.C., District of Columbia • Bethesda, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Sep 10, 2026, 4:41 PM EDT