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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:29 AM EDT

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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stress Fracture Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects

NCT02016300
View directory record Official record
Conditions
Cartilage Loss, Microfracture
Interventions
Unloader Bracing, Non-Bracing
Device
Lead sponsor
Stanford University
Other
Eligibility
15 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional Results available

Photobiomodulation Therapy for the Treatment of Lower Extremity Stress Fractures in a Military Training Setting

NCT05843864
View directory record Official record
Conditions
Metatarsal Stress Fracture, Stress Fracture of Tibia
Interventions
Photobiomodulation Therapy with Standard Physical Therapy, Sham Photobiomodulation Therapy with Standard Physical Therapy
Device · Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
17 Years to 64 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Calcium and Vitamin D Supplementation Decreases Incidence of Stress Fractures in Female Navy Recruits

NCT00476346
View directory record Official record
Conditions
Stress Fracture
Interventions
Calcium & Vitamin D
Dietary Supplement
Lead sponsor
Creighton University
Other
Eligibility
Female only
Enrollment
5,201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 25, 2015 · Synced Oct 21, 2026, 6:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Translational Research Center in Lung Cancer Disparities (TRACER) Project 2

NCT05490251
View directory record Official record
Conditions
Smoking, Smoking Behaviors, Smoking Cessation, Stress Reaction
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Enrolling by invitation Phase 4 Interventional

Fracture Recovery for Returning to Duty (Teriparatide STRONG)

NCT04589819
View directory record Official record
Conditions
Stress Fracture of Tibia or Fibula
Interventions
Teriparatide, Placebos
Drug
Lead sponsor
University of South Carolina
Other
Eligibility
Not listed
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 21, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

NCT07069478
View directory record Official record
Conditions
CBD, Cannabidiol, Stress, Acute Stress Reaction
Interventions
Stress Intervention
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 70 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Depression, Epinephrine, and Platelet Function

NCT00166114
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Escitalopram, Desipramine
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Self-Compassion Practice on Stress Reactivity Among Sexual Minority Women

NCT05949060
View directory record Official record
Conditions
Stress Reaction, Sexuality, Compassion
Interventions
Compassion Intervention
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 21, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

NCT05414708
View directory record Official record
Conditions
PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder, Posttraumatic Stress Disorder, Delayed Onset, Sleep Disturbance, Nightmare, Irritable Mood, Anger, Combat and Operational Stress Reaction, Combat Stress Disorders, Military Family, Military Operations, Emotional Regulation, Emotion Processing
Interventions
Art Therapy
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional

Use of Cell Therapy to Enhance Arthroscopic Knee Cartilage Surgery

NCT01799876
View directory record Official record
Conditions
Articular Cartilage Defect Grade III or IV of the Knee
Interventions
Autologous Cell, Standard microfracture arthroscopic surgery
Procedure
Lead sponsor
Fondren Orthopedic Group L.L.P.
Other
Eligibility
18 Years to 68 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 21, 2026, 6:29 AM EDT
Recruiting Phase 1Phase 2 Interventional

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

NCT05685368
View directory record Official record
Conditions
Race-related Stress, Depression, Anxiety, Quality of Life, Stress Reaction
Interventions
ACT for SCD
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress

NCT04562896
View directory record Official record
Conditions
Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions
Custom Carbon Fiber Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Recruiting Phase 4 Interventional

The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes

NCT06982183
View directory record Official record
Conditions
Fear of Spiders, Acute Stress Reaction
Interventions
Propranolol, Hydrocortisone, Placebo (oral), Placebo (IM)
Drug
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 40 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

rTMS to Enhance Cognitive Performance and Promote Resilience

NCT04123496
View directory record Official record
Conditions
Cognition, Stress Reaction
Interventions
rTMS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years to 55 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 21, 2026, 6:29 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition

NCT06269614
View directory record Official record
Conditions
Autism Spectrum Disorder, Adverse Childhood Experiences, Stress Reaction
Interventions
Probiotic
Dietary Supplement
Lead sponsor
Nova Southeastern University
Other
Eligibility
4 Years to 95 Months
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Racial Discrimination and Stress Response

NCT05820659
View directory record Official record
Conditions
Stress Reaction; Acute
Interventions
peer rejection task, conversation about peer rejection, and impossible puzzle task
Behavioral
Lead sponsor
Western Kentucky University
Other
Eligibility
9 Years to 99 Years
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Bowling Green, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed No phase listed Observational

Stress Reactivity Among African American Breast Cancer Survivors

NCT03881085
View directory record Official record
Conditions
Breast Cancer Female, Stress Reaction
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional

Pars Healing on MRI

NCT07215845
View directory record Official record
Conditions
Pars Interarticularis Stress Fracture, Pars Interarticularis Stress Injury
Interventions
MRI
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
12 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Vitamin D Supplementation in RNA-seq Profiles of Single-core Prostate Samples, Among Veterans

NCT04621500
View directory record Official record
Conditions
Prostate Cancer, Vitamin D Deficiency, Stress Reaction
Interventions
cholecalciferol, Standard of Care Prostate Biopsy - collection of 13th core for RNA-seq, Standard of Care Prostate Biopsies at baseline and after one year vitamin D3 supplementation, Allostatic Load
Drug · Procedure · Diagnostic Test
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years to 75 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Oct 21, 2026, 6:29 AM EDT
Recruiting Not applicable Interventional

Extracorporeal Shockwave Therapy (ESWT) for the Management of Stress Fractures and High-grade Bone Stress Injuries (BSIs)

NCT06609265
View directory record Official record
Conditions
Bones Stress Injury, Bone Stress Fracture
Interventions
Extracorporeal shockwave treatment (ESWT)., Sham Device
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Los Angeles, California • Redwood City, California • Cambridge, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed Not applicable Interventional

The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients

NCT03938584
View directory record Official record
Conditions
Vitamin C Deficiency, Smoking, Surgery, Surgery--Complications, Wound, Wound Complication, Wound Infection, Wound Dehiscence, Wound of Skin, Mandible Fracture, Mandible Open Fracture, Mandible Closed Fracture, Mandibular Fractures, Ascorbic Acid Deficiency, Oxidative Stress, Inflammation
Interventions
Vitamin C, Placebo
Dietary Supplement · Other
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 21, 2026, 6:29 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Human Stress Response in a Simulated ED Setting

NCT04317482
View directory record Official record
Conditions
Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence, Stress, Emotional
Interventions
Standard social stress task, Stressful experience in the ED
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Transcutaneous Vagus Nerve Stimulation (tVNS) and Stress Regulation During Performance Tasks

NCT07470229
View directory record Official record
Conditions
Stress Response
Interventions
Transcutaneous Vagus Nerve Stimulation (tVNS), Evaluative Stress Task
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 21, 2026, 6:29 AM EDT
Completed No phase listed Observational Results available

A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle

NCT03087396
View directory record Official record
Conditions
Insufficiency Fractures, Stress Fracture, Stress Fracture, Ankle, Foot and Toes
Interventions
Treatment of insufficiency fractures
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
11
States / cities
Mesa, Arizona • Sun City, Arizona • Capitola, California + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 21, 2026, 6:29 AM EDT