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Showing 145–168 of 204 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery

NCT03524339
Conditions
Urinary Retention, Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Placebo oral capsule, Tamsulosin
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Cleveland, Ohio
Terminated Not applicable Interventional Results available

Effect of Peri-Urethral Stimulation on Intra-Urethral Pressure

NCT05900570
Conditions
Stress Urinary Incontinence
Interventions
Urodynamic testing with and without pudendal nerve stimulation
Diagnostic Test
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
Urinary Incontinence, Stress, Uterine Prolapse, Vaginal Prolapse
Interventions
Burch urethropexy at time of sacrocolpopexy
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Female only
Enrollment
322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
7
States / cities
Birmingham, Alabama • Maywood, Illinois • Iowa City, Iowa + 4 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

TOMUS-Trial Of Mid-Urethral Slings

NCT00325039
Conditions
Urinary Incontinence
Interventions
retropubic mid-urethral sling (TVT), transobturator mid-urethral sling (TVT-O and the Monarc)
Procedure
Lead sponsor
Carelon Research
Other
Eligibility
21 Years and older · Female only
Enrollment
597 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
11
States / cities
Birmingham, Alabama • San Diego, California • Maywood, Illinois + 7 more
Conditions
Stress Urinary Incontinence, Prolapse
Interventions
Continued Pessary Use
Device
Lead sponsor
Loyola University
Other
Eligibility
51 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Maywood, Illinois
Conditions
Stress Urinary Incontinence, Pelvic Floor Disorders
Interventions
RP sling placement, SIS placement
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older · Female only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Manhasset, New York + 3 more
Completed Phase 3 Interventional Accepts healthy volunteers

Lidocaine for Pessary Check Pain Reduction

NCT05493735
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence
Interventions
Lidocaine Hcl 2% Jelly, Placebo Jelly
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Pudendal Blocks on Voiding Dysfunction Following Slings

NCT03353714
Conditions
Stress Urinary Incontinence
Interventions
Pudendal block
Other
Lead sponsor
Michael Flynn
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Stress Incontinence, Female
Interventions
Single incision sling, Bulkamid bulking agent
Device · Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Not yet recruiting Not applicable Interventional

Trial of NASHA Dx Urethral Bulking System

NCT07850804
Conditions
Urinary Incontinence, Urinary Incontinence (UI), Urinary Incontinence , Stress, Urinary Incontinence Due to Urethral Sphincter Incompetence, Urethral Sphincter Activity, Intrinsic Sphincter Deficiency, Pelvic Floor Dysfunction
Interventions
NASHA Dx, Bulkamid
Device
Lead sponsor
Palette Life Sciences, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
5
States / cities
Tustin, California • Lincoln, Nebraska • Charlotte, North Carolina + 2 more
Conditions
Stress Urinary Incontinence, Urinary Incontinence
Interventions
Behavioral Therapy, Intravaginal Pessary, Pessary combined with behavioral therapy
Behavioral · Device
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
445 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Maywood, Illinois + 5 more
Terminated Not applicable Interventional

Vesair Clinical Trial

NCT04026347
Conditions
Stress Urinary Incontinence
Interventions
Vesair Balloon, Sham balloon placement
Device · Other
Lead sponsor
Solace Therapeutics, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
25
States / cities
Phoenix, Arizona • San Diego, California • Temecula, California + 22 more
Conditions
Urinary Incontinence
Interventions
UISH001, matching placebo
Drug
Lead sponsor
Beech Tree Labs, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
Endwell, New York • Rochester, New York • Upper Saint Clair, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Hybrid Fractional Laser Treatment for Symptoms of Urinary Incontinence

NCT03180372
Conditions
Urinary Incontinence, Stress Urinary Incontinence, Urge Incontinence
Interventions
Hybrid Fractional Laser
Device
Lead sponsor
Sciton
Industry
Eligibility
30 Years to 75 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
5
States / cities
Los Gatos, California • Pensacola, Florida • Charlotte, North Carolina + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

ProACT Therapy for the Treatment of Stress Urinary Incontinence in Males

NCT00277095
Conditions
Urinary Incontinence
Interventions
ProACT (Adjustable Continence Therapy)
Device
Lead sponsor
Uromedica
Industry
Eligibility
45 Years and older · Male only
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2017
U.S. locations
7
States / cities
Tucson, Arizona • Los Angeles, California • Pembroke Pines, Florida + 4 more
Conditions
Mixed Urinary Incontinence, Stress Urinary Incontinence, Urgency Incontinence
Interventions
OnabotulinumtoxinA (Botox ®) Injections, Saline Injections
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Stress Incontinence, Female
Interventions
With Yoni.Fit, Without Yoni.Fit
Device
Lead sponsor
Watkins Conti Products. Inc.
Industry
Eligibility
25 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Urinary Incontinence, Urinary Incontinence,Stress
Interventions
Adjustable Continence Therapy for Women (ACT)
Device
Lead sponsor
Uromedica
Industry
Eligibility
22 Years and older · Female only
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
5
States / cities
Denver, Colorado • Meridian, Idaho • Independence, Missouri + 2 more
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Sprix for Postoperative Pain Control Following Gynecologic Surgery

NCT04444830
Conditions
Post Operative Pain Control, Narcotic Use, Pelvic Organ Prolapse, Urinary Incontinence , Stress, Surgery
Interventions
Sprix
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Louisville, Kentucky
Conditions
Stress Urinary Incontinence
Interventions
lidocaine with epinephrine, Normal saline with epinephrine
Drug
Lead sponsor
West Penn Allegheny Health System
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
4
States / cities
Bethel Park, Pennsylvania • Jefferson Hills, Pennsylvania • Pittsburgh, Pennsylvania + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Group-Based Therapeutic Yoga Intervention for Urinary Incontinence in Ambulatory Older Women

NCT03672461
Conditions
Stress Incontinence, Female, Stress Incontinence, Urinary, Stress Incontinence, Urge Incontinence, Urinary Incontinence, Stress, Urinary Stress Incontinence, Urgency Urinary
Interventions
Yoga Practice Program, Physical Conditioning Program
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
45 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
Palo Alto, California • San Francisco, California
Conditions
Stress Urinary Incontinence
Interventions
duloxetine HCl
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older · Female only
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Urinary Incontinence
Interventions
VA Video Connect, MyHealtheBladder
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Female only
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Birmingham, Alabama • Decatur, Georgia • Durham, North Carolina
Conditions
Stress Urinary Incontinence
Interventions
Electric DN, NM Re-ed, Exercise
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
35 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina