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ClinicalTrials.gov public records Last synced May 22, 2026, 3:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 577 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Stress and Anxiety Clear all
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Loneliness, Mental Health Issue, Distress, Emotional, Depression, Anxiety, Stress
Interventions
Overcoming Loneliness three-week intervention, Overcoming Loneliness single-session intervention, Single-session "Sharing Feelings" program, The Blu Surfer program: a popular online content-based intervention for psychological distress, The Action Brings Change (ABC) Program (TEAM Lab version), Online help-seeking as usual, The Lonely Blu Surfer program: a popular online content-based intervention for loneliness, Overcoming loneliness SSI 8-minute version
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
16 Years and older
Enrollment
4,370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2024 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Cancer, Quality of Life, Anxiety, Depression, Hope, Coping Skills, Communication
Interventions
Promoting Resilience in Stress Management (PRISM)
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
12 Years to 24 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Paroxetine, Prolonged Exposure Therapy
Drug · Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2012 · Synced May 22, 2026, 3:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anxiety, Stress
Interventions
Meditation
Behavioral
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dover, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced May 22, 2026, 3:48 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 20 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Jazz music, No music
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced May 22, 2026, 3:48 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Depression, Anxiety Disorders, Stress Related Disorder
Interventions
Not listed
Lead sponsor
Singula Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Physical Activity, Psychosocial Stressors
Interventions
Physical Activity for Life (PAL)
Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
65 Years to 100 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Uniontown, Alabama
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced May 22, 2026, 3:48 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Critical Illness
Interventions
Live music, Recorded music, Usual care
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
2 Months to 17 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced May 22, 2026, 3:48 AM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Depressive Disorder, Anxiety Disorder, Stress Disorders, Post-Traumatic
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2032
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Cancer
Interventions
Cancer Distress Coach (CaDC) App, CaDC + mCoaching, mCBT
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 85 Years
Enrollment
524 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
New York, New York • Durham, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced May 22, 2026, 3:48 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anxiety and Fear, PTSD, Veteran
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Stress, Psychological, Anxiety, Burnout, Professional
Interventions
Sleep Healthy Using the Internet (SHUT-i)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 4 Interventional
View directory record Official record
Conditions
Alcoholism, Anxiety Disorders, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Panic Disorder, Obsessive-Compulsive Disorder
Interventions
Seroquel XR
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 7, 2008 · Synced May 22, 2026, 3:48 AM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
Interventions
Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anxiety, Stress
Interventions
Mindfulness Practice
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
17 Years to 42 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced May 22, 2026, 3:48 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anxiety, Distress, Emotional, Effects of Vibration, Healthy
Interventions
Neuvana 2.0 Transcutaneous Auricular Vagal Nerve Stimulation (TaVNS), Waitlist Control, Healthy Controls: Substudy Group III, Distressed Workers: Subgroup II
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced May 22, 2026, 3:48 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
Interventions
Serotonergic Psychedelic, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Hamden, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced May 22, 2026, 3:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anxiety, Depression, Stress, Wellbeing, Quality of Life
Interventions
online mental health coaching
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced May 22, 2026, 3:48 AM EDT
Suspended Not applicable Interventional
View directory record Official record
Conditions
Anhedonia, Virtual Reality, Depression, Mood Disorders, Stress, Anxiety
Interventions
Positive Virtual Reality Training
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Depression, Anxiety, PTSD, Trauma, Psychological
Interventions
Mindfulness based intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
19 Years to 35 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced May 22, 2026, 3:48 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anxiety, Stress
Interventions
Learning to BREATHE Plus, Health and wellness
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
14 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Anxiety Depression, Burnout
Interventions
Mindfulness session
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2022 · Synced May 22, 2026, 3:48 AM EDT
Suspended Not applicable Interventional
View directory record Official record
Conditions
Depressive Disorders, Anxiety Disorders
Interventions
Unified Protocol for The Treatment of Emotional Disorders
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Los Altos, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced May 22, 2026, 3:48 AM EDT