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Showing 1–24 of 111 matching trials from the live ClinicalTrials.gov search.
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Conditions
Aphasia, Dysgraphia, Anomia, Agrammatism, Stroke
Interventions
Treatment Focusing on Naming Objects, Treatment Focusing on Improving Spelling Abilities, Treatment Focusing on Improving Sentence Processing, No Treatment
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
35 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
4
States / cities
Chicago, Illinois • Baltimore, Maryland • Boston, Massachusetts + 1 more
Conditions
Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia, Non-fluent, Aphasia Following Cerebral Infarction, Aphasia Following Nontraumatic Intracerebral Hemorrhage
Interventions
High-intensity physical exercise, Low-intensity physical exercise
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
4
States / cities
Berkeley, California • Hayward, California • San Francisco, California
Conditions
Aphasia
Interventions
Choir singing, Usual care
Behavioral · Other
Lead sponsor
University of Ottawa
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Aphasia, Broca's Aphasia
Interventions
tDCS
Device
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Charleston, South Carolina • Columbia, South Carolina • Salt Lake City, Utah
Conditions
Stroke, Aphasia, Apraxia of Speech
Interventions
Startle Adjuvant Rehabilitation Therapy (START)
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Conditions
Dyslexia, Acquired, Brain Injuries, Cerebrovascular Accident
Interventions
Cognitive Therapy to Improve Reading
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional

MIT Intensive Treatment Study

NCT06213376
Conditions
Stroke, Aphasia, Motor Speech
Interventions
Melodic Intonation Therapy, Video Feedback Performance Review
Behavioral
Lead sponsor
Nevada State University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Henderson, Nevada
Conditions
Aphasia, Stroke, Dyslexia, Acquired
Interventions
One-on-one treatment of reading difficulties
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Ischemic Stroke
Interventions
Imitate Therapy
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
Not listed
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Irvine, California
Conditions
Stroke
Interventions
Anodal or Cathodal tDCS, Sham, Computerized naming therapy
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Results available

Effects of rTMS on Brain Activation in Aphasia

NCT03292471
Conditions
Aphasia, Acquired
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Results available

Combining tDCS and CILT in Non-fluent Aphasia

NCT05561400
Conditions
Aphasia, Non-fluent Aphasia, Stroke, Brain Injuries
Interventions
tDCS, Placebo
Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Duluth, Minnesota
Conditions
Post-stroke Aphasia, Aphasia
Interventions
AAC for Language Recovery (AAC-LaRc)
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Aphasia
Interventions
Simultaneous music and reading lyrics, Priming with music, Control
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rocky Mount, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Overcoming Learned Non-Use in Chronic Aphasia

NCT02012374
Conditions
Stroke-induced Aphasia
Interventions
Intensive Language Action Therapy
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
21 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Amherst, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Language Processing and TMS

NCT05425615
Conditions
Stroke, Aphasia, Language
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2032
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Terminated Phase 1Phase 2 Interventional Results available

Evaluating Anodal tDCS Preceding Aphasia Therapy

NCT02249819
Conditions
Stroke, Aphasia
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Manhasset, New York
Active, not recruiting Not applicable Interventional

HD-tDCS for Phonological Impairment in Aphasia

NCT06010030
Conditions
Aphasia, Stroke
Interventions
Targeted Transcranial Direct Current Stimulation, Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Aphasia, Stroke
Interventions
Script training
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Aphasia, Stroke
Interventions
Speech and Language Therapy
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Chronic Aphasia
Interventions
HD-tDCS (Soterix Medical, Active), HD-tDCS (Soterix Medical, Sham)
Device
Lead sponsor
Soterix Medical
Industry
Eligibility
25 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Chapel Hill, North Carolina
Completed Phase 2 Interventional Results available

Speech Entrainment for Aphasia Recovery

NCT04364854
Conditions
Aphasia, Aphasia Non Fluent, Stroke
Interventions
SET (Speech Entrainment Therapy) 3 weeks, SET (Speech Entrainment Therapy) 4.5 weeks, SET (Speech Entrainment Therapy) 6 weeks, No Therapy 6 Weeks
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 81 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Charleston, South Carolina • Columbia, South Carolina • Salt Lake City, Utah
Conditions
Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
Interventions
Errorful training condition, Errorless training condition
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Terminated Not applicable Interventional Results available

Strategy Training for People With Aphasia After Stroke

NCT03593876
Conditions
Strategy Training
Interventions
Strategy Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania