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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Stuttering, Developmental Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter

NCT06181149
View directory record Official record
Conditions
Healthy Subjects, Stuttering, Developmental
Interventions
Delaying speech initiation, Auditory errors and pre-speech auditory modulation, Contributions of the speech premotor cortex to pre-speech auditory modulation, Delaying auditory feedback
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
3 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Tempe, Arizona • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Jul 21, 2026, 7:26 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Development of Stuttering in Young Children

NCT06578416
View directory record Official record
Conditions
Stuttering, Stuttering, Childhood, Stuttering, Developmental
Interventions
Standardized assessments of speech and language abilities
Diagnostic Test
Lead sponsor
Michigan State University
Other
Eligibility
3 Years to 6 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 21, 2026, 7:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech

NCT05437159
View directory record Official record
Conditions
Stuttering, Developmental, Aphasia, Primary Progressive
Interventions
Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords, Anodal tDCS, Sham tDCS, Learning of non-native phoneme combinations: 8 training sessions
Behavioral · Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
6 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 21, 2026, 7:26 PM EDT
Suspended Phase 3 Interventional Accepts healthy volunteers

A Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Tolerability of Asenapine With Flexible Dosing From 5mg to 20mg in Adults With Developmental Stuttering

NCT01684657
View directory record Official record
Conditions
Stuttering
Interventions
Asenapine
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Jul 21, 2026, 7:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

NCT07459803
View directory record Official record
Conditions
Stuttering, Developmental, Dyslexia, Healthy Participants
Interventions
Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation, Sustained F0 auditory feedback perturbation, Reflexive somatosensory perturbation, Anodal tCS targeting pSTG and vSSC, Anodal tCS targeting left or right vPMC, Sham tCS targeting pSTG or vSSC, Sham tCS targeting left vPMC or right vPMC
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 21, 2026, 7:26 PM EDT
Recruiting Not applicable Interventional

Transcranial Alternating Current Stimulation (tACS) in Stuttering

NCT06740968
View directory record Official record
Conditions
Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
Interventions
transcranial alternating current stimulation (tACS)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Jul 21, 2026, 7:26 PM EDT
Recruiting Not applicable Interventional

Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering

NCT07180628
View directory record Official record
Conditions
Stutter, Stuttering, Adult, Stuttering, Stuttering, Developmental
Interventions
Speech Production During functional magnetic resonance imaging (MRI)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 7:26 PM EDT
Completed No phase listed Observational

Dopamine Function in Developmental Stuttering

NCT00024960
View directory record Official record
Conditions
Developmental Stuttering
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 7:26 PM EDT
Completed Phase 2 Interventional

EXPRESS: Examining Pagoclone for Persistent Developmental Stuttering Study

NCT00216255
View directory record Official record
Conditions
Persistent Developmental Stuttering
Interventions
Pagoclone, Placebo
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
16
States / cities
Peoria, Arizona • Orange, California • Riverside, California + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2012 · Synced Jul 21, 2026, 7:26 PM EDT
Completed Phase 2 Interventional

Safety and Efficacy Study of the Investigational Drug Pagoclone, in the Treatment of Persistent Developmental Stuttering (PDS)

NCT00239915
View directory record Official record
Conditions
Persistent Developmental Stuttering
Interventions
Pagoclone
Drug
Lead sponsor
Pharmacology Research Institute
Other
Eligibility
18 Years to 65 Years
Timeline
2005 – 2006
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated May 8, 2012 · Synced Jul 21, 2026, 7:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Brain Activity During Speech Production and Speech Perception

NCT00004991
View directory record Official record
Conditions
Developmental Articulation Disorder, Stuttering
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
6 Years to 65 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 7:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Characteristics of Idiopathic Familial Speech Disorders

NCT00001551
View directory record Official record
Conditions
Developmental Articulation Disorder, Speech Disorder, Stuttering
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
375 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1996
U.S. locations
2
States / cities
College Park, Maryland • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 7:26 PM EDT
Terminated Not applicable Interventional Results available

Non-invasive Brain Stimulation in Adults Who Stutter

NCT03437512
View directory record Official record
Conditions
Stuttering, Developmental
Interventions
Anodal tDCS, Fluency training, Sham tDCS
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Jul 21, 2026, 7:26 PM EDT
Not yet recruiting Not applicable Interventional

Noninvasive Thalamocortical Neuromodulation With Low-Intensity Focused Ultrasound for Persistent Developmental Stuttering

NCT07668882
View directory record Official record
Conditions
Stuttering, Developmental Stuttering
Interventions
High DC LIFU, Sham
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 21, 2026, 7:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exploring the Nature, Assessment and Treatment of Stuttering

NCT05908123
View directory record Official record
Conditions
Stuttering, Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
Interventions
The Blank Center CARE Model(TM) for Individuals who Stutter
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
2 Years to 85 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2035
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jul 21, 2026, 7:26 PM EDT
Completed No phase listed Observational

Genetic Factors Related to Stuttering

NCT00001602
View directory record Official record
Conditions
Stuttering
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 7:26 PM EDT