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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Subdural Hematoma, Chronic Clear all
Recruiting Phase 1Phase 2 Interventional

Chronic Subdural Hematoma Treatment With Intra-Arterial Bevacizumab Injection

NCT06510582
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Bevacizumab 2 mg/kg, Bevacizumab 4 mg/kg
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma (STEM)

NCT04410146
View directory record Official record
Conditions
Subdural Hematoma, Chronic
Interventions
SQUID Embolization, SQUID Embolization and Surgical Evacuation, Surgical Evacuation, Standard Medical Management
Device · Procedure · Other
Lead sponsor
Balt USA
Industry
Eligibility
30 Years and older
Enrollment
319 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
25
States / cities
Phoenix, Arizona • Tucson, Arizona • Riverside, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Not yet recruiting No phase listed Observational

The CHALLENGER Registry

NCT07197840
View directory record Official record
Conditions
Chronic Subdural Hemorrhage (cSDH)
Interventions
Numen SILK coil embolization system
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 98 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Jul 21, 2026, 6:09 PM EDT
Not yet recruiting No phase listed Observational

Chronic Subdural Hematoma Embolization With Detachable Coils

NCT07291427
View directory record Official record
Conditions
Chronic Subdural Hemorrhage (cSDH)
Interventions
Balt coils: (Balt USA, LLC), MMA embolization
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Dexamethasone Versus Burr Hole Craniostomy for Symptomatic Chronic Subdural Hematoma

NCT02111785
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Dexamethasone, Burr Hole Craniostomy
Drug · Procedure
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Jul 21, 2026, 6:09 PM EDT
Recruiting No phase listed Observational

Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

NCT06181994
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
15
States / cities
Coral Gables, Florida • Jacksonville, Florida • Orlando, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional

Assessing Outcomes of Coil Embolization for Unilateral vs Bilateral Chronic Subdural Hematomas

NCT07715656
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
embolization therapy Bilateral, embolization therapy Unilateral
Device
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Not yet recruiting No phase listed Observational

Prospective Multi-center Single Arm Study for Subjects With Chronic Subdural Hematoma Treated With i-ED COILs, Either Alone or in Combination With Burr-holes or Mini-craniotomy

NCT07214623
View directory record Official record
Conditions
Chronic Subdural Hematoma, cSDH, Chronic Subdural Hematomas
Interventions
Neuro endovascular embolic coil
Device
Lead sponsor
Kaneka Medical America LLC
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Valhalla, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Phase 4 Interventional Results available

A Study on the Safety of Tranexamic Acid for the Chronic Subdural Hematoma Population

NCT02618382
View directory record Official record
Conditions
Subdural Hematoma
Interventions
Tranexamic Acid
Drug
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Jul 21, 2026, 6:09 PM EDT
Recruiting No phase listed Observational

Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center

NCT07324551
View directory record Official record
Conditions
Chronic Subdural Hematoma, Hemorrhage Brain
Interventions
Matched pair Aristotle 14 guidewire and Plato 17 microcatheter, Surgeon combination preference
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Dartmouth Middle Meningeal Embolization Trial (DaMMET)

NCT04270955
View directory record Official record
Conditions
Chronic Subdural Hematoma, Subdural Hematoma
Interventions
Embolization of the Middle Meningeal Artery, Standard of care including possible surgical evacuation of subdural hematoma
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Withdrawn No phase listed Observational

Middle Meningeal Artery Embolization for Chronic Subdural Hematoma

NCT04065113
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Middle Meningeal Artery Embolization with polyvinyl alcohol particles (PVA), Drainage of Subdural Hematoma
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma

NCT04402632
View directory record Official record
Conditions
Subdural Hematoma
Interventions
Surgical Management, Onyx™ Liquid Embolic System (LES) Embolization, Observation Only
Procedure · Device · Other
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
18 Years to 90 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
49
States / cities
Birmingham, Alabama • Tucson, Arizona • Irvine, California + 44 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional Results available

Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA

NCT04816591
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Experimental: Interventional Cohort: TRUFILL n-Butyl Cyanoacrylate (n-BCA) Liquid Embolic System, Standard of Care Surgery, Experimental: Interventional Cohort: TRUFILL n-BCA Liquid Embolic System, Standard of Care Medical Management
Device · Other
Lead sponsor
Cerenovus, Part of DePuy Synthes Products, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
31
States / cities
Birmingham, Alabama • Tucson, Arizona • Walnut Creek, California + 28 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Not listed No phase listed Observational

Effect of Different Intravenous Fluids on Post-operative Chronic Subdural Hematoma Size and Recurrence

NCT03831997
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Dextrose 5% W/ Sodium Chloride 0.225%
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Jul 21, 2026, 6:09 PM EDT
Not yet recruiting Not applicable Interventional

MMA Embolization With NeoCast for Subacute and Chronic Subdural Hematoma

NCT07541404
View directory record Official record
Conditions
Subdural Hematoma
Interventions
NeoCast Embolic System, Onyx LES, an FDA-Approved Commercial Liquid Embolic
Device
Lead sponsor
Arsenal Medical, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
New Haven, Connecticut • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Terminated Not applicable Interventional

A Study to Evaluate Endoscope-assisted, Minimally-invasive Cortical Access System for Chronic Subdural Evacuation

NCT04502745
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Minimally Invasive Cortical Access System (MICAS)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
55 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Jul 21, 2026, 6:09 PM EDT
Not listed Not applicable Interventional

Endovascular Embolization for Chronic Subdural Hematomas Following Surgical Evacuation

NCT04272996
View directory record Official record
Conditions
Chronic SDH and the Efficacy of Embolization
Interventions
Craniotomy only, Craniotomy + Endovascular embolization of the middle meningeal vessels
Procedure
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Jul 21, 2026, 6:09 PM EDT
Withdrawn Early Phase 1 Interventional

Targeting Spreading Depolarization After Chronic Subdural Hematoma Surgery (TASD)

NCT04966546
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Memantine Hydrochloride, Placebo
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Recruiting Not applicable Interventional

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

NCT06347796
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Conventional Surgery, Middle Meningeal Artery Embolization (MMAE)
Procedure · Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
40 Years to 90 Years
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
31
States / cities
Phoenix, Arizona • Jacksonville, Florida • Miami, Florida + 26 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 21, 2026, 6:09 PM EDT
Completed Not applicable Interventional

Middle Meningeal Artery Embolization for Treatment of Chronic Subdural Hematoma

NCT03307395
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Middel Meningeal Artery Embolization
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Jul 21, 2026, 6:09 PM EDT
Withdrawn Early Phase 1 Interventional

Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence

NCT03845322
View directory record Official record
Conditions
Hematoma, Subdural, Chronic
Interventions
Curcumin Pill, Placebo pills
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Jul 21, 2026, 6:09 PM EDT
Not listed Not applicable Interventional

Middle Meningeal Artery (MMA) Embolization Compared to Traditional Surgical Strategies to Treat Chronic Subdural Hematomas (cSDH)

NCT04095819
View directory record Official record
Conditions
Chronic Subdural Hematoma
Interventions
Middle Meningeal Artery procedure, Traditional Surgery
Procedure
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Summit, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Jul 21, 2026, 6:09 PM EDT