- Conditions
- Nicotine Dependence
- Interventions
- Nicotine Patch, Moclobemide
- Drug
- Lead sponsor
- Jed E. Rose
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 3
- States / cities
- Charlotte, North Carolina • Durham, North Carolina • Winston-Salem, North Carolina
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Showing 25–48
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- Conditions
- Opioid Use Disorder
- Interventions
- Recovery Connect
- Device
- Lead sponsor
- Bright Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,524 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 9
- States / cities
- Anchorage, Alaska • Wasilla, Alaska • Billings, Montana + 6 more
- Conditions
- Cannabis Dependence, Cannabis Withdrawal
- Interventions
- rimonabant, placebo
- Drug
- Lead sponsor
- The Scripps Research Institute
- Other
- Eligibility
- 21 Years to 30 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Nicotine Dependence
- Interventions
- Not listed
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 209 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder
- Interventions
- Microcurrent Neurofeedback (MCN), Standard Care for Substance Use Disorder
- Device · Behavioral
- Lead sponsor
- University of Alabama, Tuscaloosa
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Tuscaloosa, Alabama
- Conditions
- HIV Infection, Pain, Drug Dependence
- Interventions
- Not listed
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • Boston, Massachusetts
- Conditions
- Addictive Behavior, Alcohol Use Disorder, Alcohol Abuse, Drug Abuse, Drug Use Disorders
- Interventions
- Treatment - Workit Health Online Program, Control - Resource List
- Behavioral
- Lead sponsor
- Workit Health
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Stimulant Use Disorder, Substance-related Disorders
- Interventions
- Repetitive transcranial magnetic stimulation (rTMS)
- Device
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
- Interventions
- Participatory System Dynamics (PSD), Audit and Feedback (AF)
- Other
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 720 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2027
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Substance Use Disorders, Behavioral Health, Addiction Psychological, Addiction Disorders, Meditation, Mindfulness Based Stress Reduction, Prevention
- Interventions
- Mindfulness and Meditation-Based Relapse Prevention Program
- Behavioral
- Lead sponsor
- Bout Me Healing
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Boca Raton, Florida
- Conditions
- Heroin Addiction
- Interventions
- Counseling Only, Counseling + Transfer, Counseling + Methadone
- Other · Drug
- Lead sponsor
- Friends Research Institute, Inc.
- Other
- Eligibility
- 18 Years to 65 Years · Male only
- Enrollment
- 211 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2008
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Opiate Addiction
- Interventions
- Cannabidiol, Fentanyl
- Drug
- Lead sponsor
- Hurd,Yasmin, Ph.D.
- Individual
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opiate Addiction
- Interventions
- Methadone, Buprenorphine/naloxone
- Drug
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2011
- U.S. locations
- 2
- States / cities
- Buffalo, New York
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ASD, Alcohol Abuse/Dependence, Alcohol Addiction, Alcohol and Other Drug Use Disorders, Alcohol and Other Substance Use Prevention, Gambling Addiction, Gambling Disorder, Sex Abuse, Sex Behavior, Sex Crimes, Sex Disorder, Sex Disorders, Gender Dysphoria, Adult, Eating Behavior Disorders, Narcotic-Related Disorders, Narcotic Addiction, Narcissism, Psychiatric Disorder, Psychedelic Effects in Healthy Volunteers, Psychedelic Experiences, Psychedelic Drug Dependence, Marijuana Use Disorder, Marijuana Abuse and Dependence, Smoking (Tobacco) Addiction, Smoking Among Youth, Smoking Abstinence, Abstinence, Sex, Opiate Substitution Treatment, Opioid Abuse (Disorder), Opioid Abuse and Addiction, Cocaine Abuse, MDMA ('Ecstasy'), Addiction Disorders, Homeless and Low Incomes People, Refugees, Homelessness, Reliability and Validity, Anger Problems, Child Abuse, Sexual
- Interventions
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Behavioral
- Lead sponsor
- Veterans Recovery Network Inc.
- Other
- Eligibility
- 17 Years to 99 Years
- Enrollment
- 1,000,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2045
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Substance-Related Disorders, Treatment Adherence
- Interventions
- Motivational Interviewing at Intake (MII), Intake as Usual (IAU)
- Behavioral
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Alcohol Use Disorder, Obesity and Overweight, Alcohol
- Interventions
- Tirzepatide, Placebo injections
- Drug
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Opioid-Related Disorders, HIV Infections, AIDS
- Interventions
- Buprenorphine, Integrated HIV care and office-based opioid dependence treatment
- Drug · Behavioral
- Lead sponsor
- The New York Academy of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,350 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 10
- States / cities
- Tucson, Arizona • Oakland, California • San Francisco, California + 7 more
- Conditions
- Opioid Use Disorder, Clinical Decision Support
- Interventions
- Nurse prompt to complete COWS under required documentation, Refined EMBED CDS
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 267 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 3
- States / cities
- Guilford, Connecticut • New Haven, Connecticut
- Conditions
- Nicotine Use Disorder
- Interventions
- E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1), E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2), E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2), E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2), E-liquid coolant (High [2.0%] WS-3) for non-menthol (3), E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3), E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3), E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4), E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4), E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4), E-liquid coolant (High [2.0%] WS-23) for non-menthol (5), E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5), E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5), E-liquid coolant (4% WS-23) for non-menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Substance Use Disorders
- Interventions
- Recovery support as usual, Smartphone assisted relapse prevention
- Other
- Lead sponsor
- Chestnut Health Systems
- Other
- Eligibility
- 18 Years to 26 Years
- Enrollment
- 237 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2024
- U.S. locations
- 2
- States / cities
- Bloomington, Illinois • Chicago, Illinois
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Interventions
- NRP104
- Drug
- Lead sponsor
- New River Pharmaceuticals
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Smokeless Tobacco Use
- Interventions
- Nicotine Lozenges, Placebo lozenge
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 2
- States / cities
- Rochester, Minnesota • Eugene, Oregon
- Conditions
- Nicotine Use Disorder, Substance Use Disorders
- Interventions
- Active TI-NDBS, Sham TI-NDBS, tDCS
- Device · Other
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Bloomington, Indiana
- Conditions
- Opioid Dependence, Opioid Use Disorder (OUD)
- Interventions
- VK4-116, Placebo
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas