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ClinicalTrials.gov public records Last synced Nov 7, 2026, 7:55 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 505 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Abuse Problem Clear all

Conditions: Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
Interventions: Cognitive Behavioral Therapy; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: Not listed
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Substance Related Disorders, Drug Addiction, Substance Abuse
Interventions: Cash CM, Voucher CM; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 352 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: HIV, Substance Abuse
Interventions: Young Women's Health CoOp (YWHC), HIV Counseling/Testing; Behavioral
Lead sponsor: RTI International; Other
Eligibility: 16 Years to 21 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Research Triangle Park, North Carolina

Conditions: Parenting, Substance Abuse Relapse, Emotional Regulation
Interventions: DBT Skills + Parent Training; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Cocaine Dependence, Cocaine Addiction, Cocaine Abuse, Substance Abuse
Interventions: Sitting, Running, Walking; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 21 Years to 55 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Houston, Texas

Conditions: TBI, Anxiety, PTSD, Depression
Interventions: CES Therapy; Device
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older · Male only
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Substance-related Disorders, Alcohol-related Disorders
Interventions: Specialized Substance Abuse Supervision (SSAS); Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 17 Years and older
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Substance Abuse, Criminal Behavior, Mental Disorder
Interventions: mobile and technology assisted aftercare, Treatment as usual; Behavioral · Other
Lead sponsor: Florida State University; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Cocaine Dependence, Cocaine Addiction, Cocaine Abuse, Substance Abuse
Interventions: Placebo, Rivastigmine 3 mg, Huperzine A 0.4 mg, Rivastigmine 6 mg, Huperzine A 0.8 mg; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 55 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Healthy Volunteers
Interventions: ANS-6637 Oral Tablet, Placebo Oral Tablet; Drug
Lead sponsor: Amygdala Neurosciences, Inc.; Industry
Eligibility: 21 Years to 45 Years · Male only
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Substance Use Disorder, Delinquency
Interventions: Motivational Enhancement Therapy /Adol and PW for parents, Motivational Enhancement Therapy for adolescents, Drug Education for adolescents, Parenting Wisely for parents, Drug Education for adolescents; Other
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years to 17 Years
Enrollment: 239 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Substance Abuse, Cocaine Dependence
Interventions: Placebo, Bupropion XL, Abstinence Initiation, Relapse Prevention; Drug · Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2021
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: Methylphenidate, Lisdexamfetamine, Atomoxetine, Amphetamine, Dextroamphetamine; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: Not listed
Enrollment: 430,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Titusville, New Jersey

Conditions: HIV Infections
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2008
U.S. locations: 12
States / cities: Los Angeles, California • San Francisco, California • Denver, Colorado + 8 more

Conditions: Alcohol Abuse, Alcohol Dependence, Cannabis Abuse, Cannabis Dependence, Other Substance Abuse
Interventions: Adolescent group therapy, Transitional family therapy; Behavioral
Lead sponsor: The Morton Center, Inc.; Other
Eligibility: 13 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2012
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Juvenile Justice Involvement, Drug Abuse
Interventions: Middle School Success Intervention (MSS); Behavioral
Lead sponsor: Oregon Social Learning Center; Other
Eligibility: 10 Years to 12 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2013
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse, Violence, Victimization
Interventions: Test, Treat, Retain(TTR) + Women's Health CoOp (WHC), Test, Treat, Retain(TTR) only; Behavioral · Biological
Lead sponsor: RTI International; Other
Eligibility: 15 Years to 55 Years · Female only
Enrollment: 641 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Research Triangle Park, North Carolina

Conditions: Affective Disorders, Anxiety Disorders, Attention Deficit Disorder, Substance Abuse
Interventions: Cognitive Remediation, Computer Skills Training; Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 22 Years
Enrollment: 188 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Mental Illness
Interventions: Basic Vocational Services, Self-Study, Group Program; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 111 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Substance Abuse Problem
Interventions: Women-Only; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 291 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Substance Abuse
Interventions: Monitoring and Feedback Intervention; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 327 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 4
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Abuse, Mental Health, Educational Problems
Interventions: Bridges 4-week Program; Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 10 Years to 15 Years
Enrollment: 664 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Substance Use
Interventions: Rural curriculum, Classic curriculum; Other
Lead sponsor: Penn State University; Other
Eligibility: 11 Years to 15 Years
Enrollment: 2,827 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Post-Traumatic Stress Disorder, Mental Disorders, Depression
Interventions: Trauma Recovery and Empowerment Model (TREM), Usual care; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 20 Years to 60 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Baltimore, Maryland

Search by objective public record fields.

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

Contingency Management for Cocaine Dependence: Cash Versus Vouchers

Young Women's Health CoOp (Cooperative) in Cape Town

Integration of DBT Skills and Parent Training for Parents With a History of Substance Use

Exercise as a Behavioral Treatment for Cocaine Dependence

Cranial Electrotherapy Stimulation (CES) Therapy

Specialized Substance Abuse Supervision (SSAS) Versus Non-SSAS Recidivism Rates Among Nebraska Felony Drug Offenders

Feasibility of Mobile and Technology Assisted Aftercare Services for Crisis Stabilization Units

Rivastigmine and Huperzine A as Treatments for Cocaine Dependence

A Study to Evaluate the Safety of the Coadministration of ANS-6637 and Ethanol

Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study

Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence

A Study on Suicidality, Psychosis or Substance Abuse With Methylphenidate, Atomoxetine, Amphetamine/Dextroamphetamine or Lisdexamfetamine

A Study of HIV in Newly Infected Individuals

A Comparison of Adolescent Group Therapy and Transitional Family Therapy for Adolescent Alcohol and Drug Abusers

Prevention Program for Problem Behaviors in Girls in Foster Care

WHC+ (Women's Health CoOp PLUS)

Cognitive Skills Training for Homeless Youth

Evaluating Vocational Materials for Incarcerated Veterans With Mental Illness or Substance Abuse

Gender-Responsive Treatment for Women Offenders - 1

Monitoring and Feedback in Substance Abuse Treatment

Optimizing a Drug Abuse Prevention Program for Dissemination

Adaptation Processes in School-Based Substance Abuse Programs

The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women