Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 8:04 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 505 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Abuse Problem Clear all

Conditions: Reduction in Heavy Drinking in Patients With HIV
Interventions: Naltrexone, Placebo + Medication Management/Medication Coaching; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Substance-Related Disorders
Interventions: Randomized Drug Testing Trial; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions: Assessment, Educational Activity, Training; Behavioral · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Sexual Assault and Rape, Risk Behavior, Alcohol Abuse
Interventions: Surveys, Interviews, Group Discussions; Other
Lead sponsor: Womack Army Medical Center; Federal
Eligibility: 18 Years to 26 Years · Male only
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Fort Bragg, North Carolina

Conditions: Housing Problems, Household Substance Abuse, Substance Use Disorders, Harm Reduction
Interventions: Technology-based Intervention; Behavioral
Lead sponsor: Oregon Research Behavioral Intervention Strategies, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Springfield, Oregon

Conditions: Impulsive Behavior, Substance Abuse, HIV Risk Behavior, Anxiety, Depression, Criminogenic Thinking
Interventions: REVAMP, TAU; Behavioral
Lead sponsor: George Mason University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Interventions: Mental Health Assessments and Computerized Cognitive Test, MRI scan; Behavioral · Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 13 Years to 25 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Medication Adherence
Interventions: Automated Adherence Monitoring System; Other
Lead sponsor: California Pacific Medical Center Research Institute; Other
Eligibility: 18 Years to 60 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Drug Abuse
Interventions: Brief advice, Brief Intervention plus Booster, Brief Intervention; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 417 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
Interventions: NDGameSquad; Behavioral
Lead sponsor: Merrimack College; Other
Eligibility: 11 Years to 18 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Boston, Massachusetts • Marblehead, Massachusetts

Conditions: Dual Diagnosis, Cocaine Abuse, Cocaine Dependence, Polysubstance Abuse
Interventions: ATM, Individual Drug Counseling; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 2
States / cities: Bridgeport, Connecticut • Hartford, Connecticut

Conditions: Substance Abuse, Substance Dependence, Depressive Disorder
Interventions: Group interpersonal psychotherapy (IPT-G), Psychoeducation on co-occurring disorders (PSYCHOED); Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Cranston, Rhode Island

Conditions: Substance-Related Disorders, Drug Addiction, Substance Abuse
Interventions: Community Reinforcement and Family Training, Al-Anon Facilitation; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 12 Years and older
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cocaine-Related Disorders, Substance-Related Disorders
Interventions: Carbamazepine; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1992 – 1997
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Stimulant Abuse, HIV Prevention, Substance Abuse
Interventions: IMPACT, Standard of Care; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older · Male only
Enrollment: 205 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: Miami, Florida • Boston, Massachusetts

Conditions: HIV Infections
Interventions: IBFT /HIV prevention, IBFT; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 15 Years to 20 Years
Enrollment: 111 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2013
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Depression, Substance Abuse, Substance Use, Neuroimaging, Dual Diagnosis
Interventions: Creatine monohydrate; Drug
Lead sponsor: Perry Renshaw; Other
Eligibility: 13 Years to 64 Years · Female only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Hepatitis C, Medication Adherence
Interventions: Intensive Models (mDOT and CGT) of HCV Care; Other
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Alcohol Dependence
Interventions: Placebo, Naltrexone, Naltrexone + Aripiprazole; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 70 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cocaine Dependence
Interventions: Citalopram, Placebo; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder, Substance Abuse
Interventions: Adolescent Skills Parent Management Parent-Adol Negotiation, Treatment as Usual; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 11 Years to 14 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Maternal Substance Use, Child Abuse and Neglect
Interventions: Mentalizing Therapy for Substance Using Mothers, Standard Parent Education for Substance Using Mothers; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Marijuana Dependence
Interventions: Oxytocin, Saline; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Substance Use Disorders
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: Baltimore, Maryland • Catonsville, Maryland

Search by objective public record fields.

Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and Prevention

Mentored Clinical Career Award in Adolescent Substance Abuse

Stop Addiction Stigma

Piloting ProHealth: A Program for Male Soldiers on Sex, Dating and Alcohol-Use at Fort Bragg

Innovating Technology Solutions for Residents in Support Housing Communities w SUD Through Community-Engaged Research

Evaluation of Re-Entry Values and Mindfulness Program (REVAMP) With Jail Inmates

Brain Imaging in Early Psychosis

Adherence Monitoring For Substance Abuse Clinical Trials

Multidisciplinary Approach to Reduce Injury and Substance Abuse

Expanded Game Squad for Neurodiverse Youth

Abstinence-Linked Money Management Multisite

Group Therapy for Women Prisoners With Comorbid Substance Use and Depression

Family Training Program for Parents of Substance Using Adolescents

Carbamazepine Treatment of Cocaine Dependence - 1

Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse

Preventing HIV/Aids in Drug Abusing Youth

Creatine as a Treatment Option for Depression in Methamphetamine Using Females

Intensive Models of HCV Care for Injection Drug Users

An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence

Brain Function and Structure in Cocaine Dependence

Home Based Treatment for Drug Use in Early Adolescents

Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers

Effect of Oxytocin on Stress in Marijuana Users

Screening Protocol for the Evaluation of Research Participants at the Maryland Psychiatric Research Center (MPRC)