Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 8:49 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 505 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Abuse Problem Clear all

Conditions: Feedback, Psychological, Clinical Trial, Substance Abuse
Interventions: Web-based PFI, Assessment Only; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 25 Years
Enrollment: 843 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Substance Abuse
Interventions: Contingency management; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Nicotine Use Disorder, Smoking Cessation, Smoking Cessation Intervention
Interventions: Enhanced Courage to Quit; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 26 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Substance Abuse, Intravenous, Prevention and Control
Interventions: Break the Cycle Intervention, Bacterial Infection Prevention; Behavioral
Lead sponsor: New York University; Other
Eligibility: 18 Years and older
Enrollment: 402 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Adherence, Substance Abuse
Interventions: PM Component Text Reminders; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 16 Years to 29 Years
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 2
States / cities: La Jolla, California • Detroit, Michigan

Conditions: Patients With Substance Abuse, Healthcare Provider Attitudes
Interventions: Training on motivational interviewing; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: Alcohol Abuse, Alcohol Dependence
Interventions: Motivation Enhancement Therapy (MET), Peer-Twelve Step Facilitation (P-TSF); Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Schizophrenia, Bipolar Disorder, Substance-related Disorders
Interventions: Family Intervention for Dual Diagnosis, Family psychoeducation program; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 2
States / cities: Santa Fe Springs, California • Chelsea, Massachusetts

Conditions: Cocaine Abuse, Cocaine-Related Disorders
Interventions: Not listed
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 55 Years
Enrollment: 192 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Substance Abuse Detection
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 1 Year to 18 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Davis, California

Conditions: PTSD
Interventions: Paroxetine CR; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Posttraumatic Stress Disorder, Substance Abuse
Interventions: CBT and exposure therapy for PTSD, Treatment as Usual; Behavioral · Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 70 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Depression, Substance-Related Disorders
Interventions: CAST-T/HSTS, Brief Intervention; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 12 Years to 15 Years
Enrollment: 497 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid-related Disorders, HIV Infections, Hepatitis C, Chronic, Depression
Interventions: MET/CBT based individualized counseling, Buprenorphine; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cocaine Dependence
Interventions: Contingency management; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Prescription Drug Abuse (Not Dependent)
Interventions: prescription drug-abuse education smartphone application; Behavioral
Lead sponsor: Naval Health Research Center; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: San Diego, California

Conditions: Substance Abuse, Substance Dependence
Interventions: Behavioral Intervention; Behavioral
Lead sponsor: Northwell Health; Other
Eligibility: 16 Years to 44 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 2
States / cities: Glen Oaks, New York • Manhasset, New York

Conditions: Substance Abuse
Interventions: Standard Treatment As Usual (TAU), CBT4CBT program; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Substance Abuse, Suicide, Depression
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS), sham rTMS; Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 64 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Overweight, Obesity
Interventions: Not listed
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 23 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
Interventions: NRP104; Drug
Lead sponsor: New River Pharmaceuticals; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Abuse, Adolescent Behavior, Juvenile Delinquency Unspecified
Interventions: JUST; Other
Lead sponsor: Pepperdine University; Other
Eligibility: 13 Years to 17 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Yuma, Arizona

Conditions: Overdose, Opioid-related Disorders, Drug Addiction, Drug Abuse, Substance Abuse, Opioid Use, Unspecified, Opioid Dependence, Drug Overdose
Interventions: TTIP-PRO; Behavioral
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Signs and Symptoms, Clinical Supervision
Interventions: SAU, MIA: STEP; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: West Haven, Connecticut

Search by objective public record fields.

Personalized Health Assessment Related to Medications (Project PHARM)

Group-Based Contingency Management for Substance Abuse Treatment - 1

Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites

Break the Cycle: Prevention for Reducing Initiation Into Injection Drug Use

Targeting PM to Improve HIV Adherence in Adolescents at Risk for Substance Abuse

Healthcare Provider Attitudes Towards Patients With Substance Use Before and After Implementation of the SBIRT Model in the Emergency Room

Facilitating Aftercare for Alcohol Detox Patients

Family Intervention for Mental Illness and Substance Abuse

Impulsivity, Brain Function, and Substance Abuse Treatment in Cocaine Dependent Individuals

Optimizing Toxicological Screening in Drug Endangered Children

Paroxetine Treatment in Outpatients With Comorbid PTSD and Substance Dependence

Multicomponent Cognitive Behavioral Therapy(CBT) for Posttraumatic Stress Disorder (PTSD) and Substance Abuse

Middle School to High School Transition Project: Depression and Substance Abuse Prevention

Project BEST: Buprenorphine Entry Into Substance Abuse Treatment

Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2

Mobile Application for Prescription Drug-Abuse Education (MAPDE)

Improving Outcomes in Psychosis Associated With Substance Use Using Aripiprazole

Computer Based Training in CBT in Primary Care

Functional Connectivity Alterations in Suicidal Patients Among Opioid Users

Relationship of Adverse Childhood Experiences to Overweight and Obesity

Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories

An Evaluation of JUST Court in Yuma County, AZ

Phone Interview to Prevent Recurring Opioid Overdoses

Effectiveness of Motivational Interviewing Supervision in Community Programs