Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 457–480 of 505 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Abuse Problem Clear all

Conditions: Substance Abuse, HIV Risk, Criminogenic Thinking, Shame, Guilt, Empathy
Interventions: MI plus IOC group intervention, Motivational Interview only; Behavioral
Lead sponsor: George Mason University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: Cocaine Dependence
Interventions: Caffeine 150 MG, Placebo, Amphetamine, Caffeine 300 MG; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
Interventions: Varenicline, Placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Risk Behavior, Substance Abuse, Delinquency
Interventions: Day Treatment MDFT-HIV, Day Treatment SAU; Other
Lead sponsor: University of Miami; Other
Eligibility: 13 Years to 18 Years
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Opioid Abuse, Substance Abuse
Interventions: standard treatment, MTS (Mobile Therapeutic System), mobile control; Behavioral
Lead sponsor: National Development and Research Institutes, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 219 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Long Island City, New York

Conditions: Suicide, Attempted, Suicide, Ideation, Depression, Substance Abuse
Interventions: CBT-RP (relapse prevention) + Enhanced TAU, Enhanced TAU Alone; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 13 Years to 19 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Alcohol Withdrawal, Substance Use Disorders
Interventions: Patient navigation, Motivational interviewing (MI); Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 206 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Fairbanks, Alaska

Conditions: Alcoholism, Alcohol Dependence, Alcohol Abuse
Interventions: Topiramate, Zonisamide, Levetiracetam, Sugar Pill; Drug
Lead sponsor: Boston Medical Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance Abuse
Interventions: MTI, Minimal Transitional Intervention, GTI, Group Transitional Intervention, STI, Systems Transitions Intervention; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years to 18 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2014
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Substance Abuse
Interventions: Cognitive Behavioral Intervention; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 389 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: Dover, Delaware • Wilmington, Delaware • Collingswood, New Jersey + 1 more

Conditions: Substance Use, Substance Abuse, Suicide, Adolescent
Interventions: WisePath for Teens, Peer Support Services (PSS), Control; Other · Behavioral · Device
Lead sponsor: Evidence-Based Practice Institute, Seattle, WA; Industry
Eligibility: 13 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Baltimore, Maryland • Seattle, Washington

Conditions: Addiction
Interventions: Mobile Continuing Care; Behavioral
Lead sponsor: Azusa Pacific University; Other
Eligibility: 12 Years to 24 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Azusa, California

Conditions: Opiate Addiction, Refractory Pain
Interventions: buprenorphine/naloxone; Drug
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: HIV Infections, Substance Abuse, Sexually Transmitted Diseases
Interventions: EDGE counseling, no maintenance, EDGE counseling, plus maintenance, Attention control; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Male only
Enrollment: 429 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Drug/Substance Abuse/Addiction, Alcohol Abuse/Addiction
Interventions: Oxford House, Safe Haven, Usual aftercare; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Substance Abuse Detection, HIV, Hepatitis B, Hepatitis C, Brief Intervention, HIV Infections
Interventions: Brief motivational intervention; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 1,030 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Substance Abuse, Domestic Violence, HIV/AIDS
Interventions: HoMBReS intervention, Families Talking Together (FTT), Diabetes Prevention Intervention; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older · Male only
Enrollment: 244 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Substance Abuse, Post-partum Depression, Depression
Interventions: Family Spirit Intervention; Procedure
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 12 Years to 19 Years · Female only
Enrollment: 322 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 5
States / cities: Fort Defiance, Arizona • San Carlos, Arizona • Tuba City, Arizona + 2 more

Conditions: Gambling
Interventions: 10 minutes of psycho-education, 10 minutes of brief advice, four 50-minute individual therapy sessions of MET & CBT; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Substance Abuse, Disorders
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 55,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Acquired Immune Deficiency Syndrome Virus, Hepatitis C, Drug Abuse
Interventions: MI-based HIV Risk Reduction; Other
Lead sponsor: Michele Staton; Other
Eligibility: 18 Years and older · Female only
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Hazard, Kentucky

Conditions: Substance Use Disorders
Interventions: DARTNA, Treatment-As-Usual; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alcohol Dependence, Alcohol Abuse, Substance Abuse
Interventions: Carisbamate, Placebo; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 55 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions: Integrated Care for Smoking Cessation in PTSD patients, Standard of Care; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 943 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 11
States / cities: Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more

Search by objective public record fields.

Jail-Based Impact of Crime Intervention

Caffeine and Cocaine

Varenicline for Methamphetamine Dependence

Juvenile Offender HIV Prevention and Drug Abuse Services

Mobile Psychosocial Interventions for MMT Clients

Relapse Prevention for Suicidal Dually Diagnosed Youths

NCARE, Transition to Recovery

Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism

Transitional Treatment of Adolescents in Family Therapy

Evaluation of Web-Based Recovery Monitoring With Clinical Alerts

Mobile Technology to Reduce Teen Substance Misuse

Mobile Continuing Care Approach for Youth

Buprenorphine as a Treatment in Opiate Dependent Pain Patients

Behavior Change and Maintenance Intervention for HIV+ MSM Methamphetamine Users

Evaluating Alternative Aftercare Models for Ex-offenders

Brief Intervention for Drug Misuse in the Emergency Department

Hispanic Men Building Respect Education and Safety/ HoMBRES Manteniendo Respeto, Educacion y Seguridad.

Cradling Our Future Through Family Strengthening Study

Brief Therapies for Problem Gambling Substance Abusers

Screening Protocol for the Evaluation of Research Participants

Brief Intervention for Rural Women at High Risk for HIV/HCV

Drum-Assisted Therapy for Native Americans

Carisbamate as a Potential Treatment for Alcohol Dependence

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder