Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 6:48 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 505 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Abuse Problem Clear all

Conditions: Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions: Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO); Behavioral
Lead sponsor: Partnership to End Addiction; Other
Eligibility: 21 Years to 75 Years
Enrollment: 730 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance-Related Disorders, Alcohol-Related Disorders, Marijuana Abuse
Interventions: Usual care, Computer-delivered ACRA; Behavioral
Lead sponsor: National Development and Research Institutes, Inc.; Other
Eligibility: 12 Years to 18 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Methamphetamine Dependence, Methamphetamine Abuse, Substance Abuse
Interventions: Placebo, Varenicline; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 55 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Substance Abuse, Substance Dependence, Substance, Addiction, Alcohol Abuse
Interventions: Linkage patient activation intervention; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 504 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Anxiety Depression, Alcohol Abuse, Substance Abuse, Anger, Sleep Disturbance, Stress Reaction
Interventions: CBD Isolate, Full Spectrum CBD Oil, Broad-Spectrum CBD Oil, Placebo Oil; Dietary Supplement
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 70 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Substance Related Disorders
Interventions: cSBA - New England, USA, cSBA - Prague, CZR; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 18 Years
Enrollment: 2,695 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 5
States / cities: Boston, Massachusetts • Cambridge, Massachusetts • Worcester, Massachusetts + 2 more

Conditions: HIV Infection, Substance Abuse
Interventions: Trans-theoretical Process of Change Model-self, Trans-theoretical Process of Change Model - interviewer; Behavioral
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 39 Years
Enrollment: 750 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Substance Abuse, Substance Dependence
Interventions: Chestnut Bloomington Outpatient (CBOP), Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7), Assertive Continuing Care (ACC); Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 12 Years to 18 Years
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Bloomington, Illinois

Conditions: Diabetes, Cardiovascular Disease, Substance Abuse Disorder, Mental Health Disorder
Interventions: Co-developed IT intervention; Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: Not listed
Enrollment: 6,767 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Medical Education
Interventions: Online education; Behavioral
Lead sponsor: Medical Directions, Inc; Industry
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: HIV
Interventions: PATH For Triples, Treatment as Usual; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Abuse
Interventions: Assets Getting To Outcomes; Other
Lead sponsor: RAND; Other
Eligibility: 18 Years to 65 Years
Enrollment: 376 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Delinquency, Substance Abuse
Interventions: RAYS Intervention; Behavioral
Lead sponsor: Pro-Change Behavior Systems; Other
Eligibility: 13 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 5
States / cities: Cedar Rapids, Iowa • Davenport, Iowa • Des Moines, Iowa + 2 more

Conditions: Substance Use Disorders, Mental Illness
Interventions: SBIRT, Health Education; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 1,080 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 2
States / cities: Los Angeles, California • Oxnard, California

Conditions: Cannabis Use Disorder, Severe
Interventions: TMS - Sham, TMS - Active iTBS, TMS - Active cTBS; Device
Lead sponsor: Auburn University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Auburn, Alabama

Conditions: HIV Infections, Hepatitis, Sexually Transmitted Infections
Interventions: Traditional Prevention, Web-based Prevention; Behavioral
Lead sponsor: National Development and Research Institutes, Inc.; Other
Eligibility: 12 Years to 18 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 3
States / cities: Brooklyn, New York • Jamaica, New York • The Bronx, New York

Conditions: Schizophrenia, Schizoaffective Disorder, Psychotic Disorder, Substance Abuse, Alcohol Abuse
Interventions: Quetiapine; Drug
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 4
States / cities: Augusta, Georgia • Lebanon, New Hampshire • Manchester, New Hampshire

Conditions: HIV Infections
Interventions: Focus Group, First Intervention Trial, Intervention Trial 2; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 24 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 3
States / cities: Los Angeles, California • New York, New York • Philadelphia, Pennsylvania

Conditions: Alcohol Dependence, Alcohol Consumption
Interventions: Brief Intervention (adaptation of motivational interviewing); Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance Abuse
Interventions: Centervention-ATOD (CV-ATOD); Other
Lead sponsor: 3-C Institute for Social Development; Industry
Eligibility: 11 Years to 65 Years
Enrollment: 327 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse, Drug Abuse, Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal Syndrome, Drug Abuse in Pregnancy
Interventions: Buprenorphine Injection, Buprenorphine Sublingual Product; Drug
Lead sponsor: T. John Winhusen, PhD; Other
Eligibility: 18 Years to 41 Years · Female only
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 12
States / cities: Jacksonville, Florida • Boston, Massachusetts • Albuquerque, New Mexico + 8 more

Conditions: Substance Abuse
Interventions: Contingency management; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Schizophrenia, Dual Diagnosis, Schizoaffective Disorder, Psychotic Disorder, Cannabis Abuse
Interventions: Clozapine, Treatment as usual; Drug
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2009
U.S. locations: 4
States / cities: Los Angeles, California • Kansas City, Missouri • Manchester, New Hampshire + 1 more

Conditions: Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
Interventions: CHRP-BB; Other
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years and older
Enrollment: 237 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Search by objective public record fields.

Messaging Interventions to Reduce Alcohol Problems Project

Computer-delivered Psychosocial Intervention for Adolescent Substance Use Disorders

Varenicline as a Treatment for Methamphetamine Dependence

Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care

CBD Oil for Reducing Emotional Impact of COVID-19

Screening and Brief Advice to Reduce Teen Substance Use

A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV

Adolescent Outpatient and Continuing Care Study

Reverse Innovation and Patient Engagement to Improve Quality of Care and Patient Outcomes

Online Primary Care Physician (PCP) Training in Screening, Brief Intervention, Referral, and Treatment

PATH For Triples Study: Medication and Lifestyle Adherence for HIV+ Patients

Enhancing Prevention Capacity With Developmental Assets and Getting to Outcomes

Computerized Stage-Matched Intervention for Juvenile Offenders

Screening, Brief Intervention and Referral to Treatment for Substance Abuse in Mental Health Treatment Settings

Cannabis and Processing Emotions Study

Comparative Effectiveness of Web-based Versus Traditional Adolescent HIV Prevention

Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder

Integrated Treatment of Marijuana Abuse for HIV+ Youth

ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems

Efficacy of Centervention-ATOD: An Implementation Tool for Dissemination of Evidence-based Programs for Substance Abuse

Medication Treatment for Opioid Use Disorder in Expectant Mothers

Training Therapists to Administer Contingency Management-Patient Phase - 3

Treatment of Schizophrenia and Comorbid Cannabis Use Disorder: Comparing Clozapine to Treatment-as-Usual

Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs