Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 7:32 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 505 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Abuse Problem Clear all

Conditions: Cocaine Dependence
Interventions: Propranolol, Placebo; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Abuse, Mindfulness
Interventions: Master Mind; Behavioral
Lead sponsor: Innovation Research & Training; Other
Eligibility: 8 Years to 12 Years
Enrollment: 518 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Bipolar Disorder
Interventions: Lithium, Divalproex, Placebo; Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 16 Years to 65 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2006
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Methamphetamine Dependence
Interventions: Text messages; Behavioral
Lead sponsor: New Leaf Treatment Center; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Lafayette, California

Conditions: Substance Abuse, Dual Diagnosis
Interventions: Advisor-Teller Money Management-Substance Abuse Counselling; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Depression, Anxiety, Externalizing Symptoms, Substance Abuse
Interventions: CATCH-IT, AMPE; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 13 Years to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 4
States / cities: Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts

Conditions: Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized, Substance Abuse, Alcohol Abuse
Interventions: Motivational + Family Check-up (MET+FCU), Psychoeducation; Behavioral · Other
Lead sponsor: Brown University; Other
Eligibility: 12 Years to 18 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 2
States / cities: Providence, Rhode Island

Conditions: Alcohol Dependence
Interventions: Mindfulness Based Relapse Prevention for Alcohol Dependence, "Wait-list" control; Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
Interventions: Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing; Behavioral
Lead sponsor: RTI International; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 652 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 4
States / cities: Durham, North Carolina • Greensboro, North Carolina • High Point, North Carolina + 1 more

Conditions: Schizophrenia, Dual Diagnosis, Psychotic Disorder, Cannabis Use Disorder
Interventions: Marijuana, Dronabinol, Placebo; Drug
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years to 55 Years
Enrollment: 263 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2021
U.S. locations: 2
States / cities: Lebanon, New Hampshire • Burlington, Vermont

Conditions: Opioid Use Disorder
Interventions: Exablate Model 4000 Type 2.0/2.1; Device
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Alcohol Dependence
Interventions: Not listed
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 60 Years · Male only
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Substance Abuse, HIV
Interventions: Computer-facilitated HIV intervention, Attention Control; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 371 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder, Drinking, Alcohol, Substance Use
Interventions: Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI); Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Cincinnati, Ohio • Columbus, Ohio

Conditions: Continuous Methamphetamine Abuse
Interventions: Prazosin; Drug
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Depression, Chronic Pain, Substance Abuse
Interventions: co-administration of TMS and infused ketamine; Other
Lead sponsor: The Neuroscience Center, LLC; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Deerfield, Illinois

Conditions: Cocaine Dependence, Cocaine Abuse, Cocaine Addiction, Substance Abuse
Interventions: Modafinil and Escitalopram, Placebo, Modafinil, Escitalopram; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 55 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: HIV (Human Immunodeficiency Virus), Substance Abuse Disorder
Interventions: Community Coalition CLS Workgroup/Network of Providers, Tech-mediated Training and Service Delivery, Multidisciplinary Implementation Team with Champion, Tech-mediated Peer Navigation Enhanced Case management (NCM); Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Kingston, New York

Conditions: Contraceptive Usage, Contraception
Interventions: SexHealth Mobile; Behavioral
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 4
States / cities: Kansas City, Missouri

Conditions: Depression, Anxiety, Insomnia
Interventions: Nexalin Brain Stimulator, Fischer Wallace Stimulator, David Delight Stimulator, Relaxation Therapy; Device · Behavioral
Lead sponsor: Behavioral Health of the Palm Beaches; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: North Palm Beach, Florida

Conditions: Recurrence, Smoking Cessation, Substance-Related Disorders
Interventions: Varenicline, Placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: HIV/AIDS, Substance Abuse
Interventions: Directly administered antiretroviral therapy; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 2
States / cities: Hartford, Connecticut • New Haven, Connecticut

Conditions: Substance Use, Substance Abuse, Suicide
Interventions: Thiwáhe Gluwáš'akapi, Woyute Waśte; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 10 Years to 85 Years
Enrollment: 552 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: High Blood Pressure, Substance Abuse
Interventions: Usual Care, Contingency Management; Other · Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Farmington, Connecticut

Search by objective public record fields.

Effects of Propranolol on Responses to Drug-Related Imagery Scripts

Master Mind Program Evaluation Study

Lithium and Divalproex for the Treatment of Comorbid Rapid Cycling Bipolar Disorder and Substance Abuse Disorder

A Cognitive Behavioral Therapy-Based Text Messaging Intervention for Methamphetamine Dependence

Effectiveness of Advisor-Teller Money Manager

Primary Care Internet-Based Depression Prevention for Adolescents (CATCH-IT)

Substance Use Interventions for Truant Adolescents

Mindfulness Meditation for Health

NC Young Women's CoOp

Cannabis, Schizophrenia and Reward: Self-Medication and Agonist Treatment?

Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD)

Stress, Hypothalamic-pituitary-adrenal (HPA) Dysfunction, and Relapse in Alcoholism

Reducing High Risk Behavior in Treatment Court

The STop UNhealthy Substance Use Now Trial

Monoamine Antagonist Therapies for Methamphetamine Abuse Prazosin

Neuromodulation to Facilitate the Effect of Ketamine

Modafinil - Escitalopram Study for Cocaine Dependence

TechMPower: Advancing HIV/SUD Care and Service Delivery for People in Re-entry

SexHealth Mobile: Integrating a Mobile Clinic and a Point-of-care Contraception Counseling and Access

Evaluating Neuromodulation Technologies in Early Recovery

Relapse Prevention With Varenicline

Directly Observed Therapy for Community-Released HIV+ Prisoners

Evaluation of Thiwáhe Gluwáš'Akapi Substance Use Prevention Program

Improving Antihypertensive Medication Adherence