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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:41 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Smoking, Tobacco Use Disorder
Interventions: Not listed
Lead sponsor: Memorial Hospital of Rhode Island; Other
Eligibility: Female only
Enrollment: 252 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1997 – 2002
U.S. locations: 1
States / cities: Pawtucket, Rhode Island

Conditions: Smoking, Nicotine Dependence
Interventions: Nicotine e-cigarette, Non-nicotine e-cigarette; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: HIV Infections, Depression, Substance-Related Disorders
Interventions: Cognitive Behavioral Therapy, Psychopharmacology; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 175 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2003
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Underage Drinking, Alcohol Use, Underage
Interventions: REAL Parenting, Active Control Materials; Behavioral · Other
Lead sponsor: Real Prevention, LLC; Industry
Eligibility: 15 Years to 18 Years
Enrollment: 612 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Clifton, New Jersey

Conditions: Smoking Cessation
Interventions: rTMS Active 20Hz, rTMS Sham; Device
Lead sponsor: The City College of New York; Other
Eligibility: 21 Years to 65 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Bullying, Cyberbullying, Substance Use, Substance Abuse
Interventions: LST MS curriculum+ Bullying/Cyberbulling serious game, LST MS curriculum; Behavioral
Lead sponsor: National Health Promotion Associates, Inc.; Industry
Eligibility: 11 Years to 14 Years
Enrollment: 3,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Opioid-use Disorder, Opioid Dependence, Attitude of Health Personnel
Interventions: Online training; Behavioral
Lead sponsor: HealthPartners Institute; Other
Eligibility: Not listed
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Bloomington, Minnesota

Conditions: HIV/AIDS, Substance Use, Bisexuality
Interventions: HIV and substance use prevention; Behavioral
Lead sponsor: Rosalind Franklin University of Medicine and Science; Other
Eligibility: 14 Years to 17 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: North Chicago, Illinois

Conditions: Tobacco Use Disorder, Cigarette Smoking
Interventions: Sublingual tablet 4 mg versus Nicorette Lozenge 4mg; Drug
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years to 45 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Raleigh, North Carolina

Conditions: Depression, Anxiety, Insomnia, Substance Abuse
Interventions: TES Treatment, TES-SHAM Treatment; Device
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Belle Mead, New Jersey

Conditions: Alcohol Drinking, Binge Drinking, Text Messaging
Interventions: Brief Alcohol Intervention, Automated and Targeted Text Messages; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 7,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Smokeless Tobacco Use
Interventions: nicotine replacement therapy (nicotine patches), placebo NRT; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 55 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Tobacco Dependence
Interventions: Reduced Nicotine Content Cigarettes, Same Nicotine Content Cigarettes; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 280 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Hershey, Pennsylvania

Conditions: Behavioral Health
Interventions: Episodic Future Thinking; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: Not listed
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Attention Deficit Hyperactivity Disorder
Interventions: Brief Early Intervention, Parent Training with Adolescent Cognitive Behavioral Therapy, Methylphenidate; Behavioral · Drug
Lead sponsor: Florida International University; Other
Eligibility: 12 Years to 16 Years
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Nicotine Dependence, Major Depressive Disorder
Interventions: Varenicline, BASC, Standard treatment; Drug · Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 2
States / cities: Chicago, Illinois • Philadelphia, Pennsylvania

Conditions: Opioid-use Disorder, Medication Adherence, Health Care Utilization
Interventions: Behavioral Activation (BA) Therapy, Substance Abuse and Health Navigation Counseling, Medications for Opioid Use Disorder; Behavioral · Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Tobacco Dependence, Obesity, Mental Illness
Interventions: NH Medicaid Incentives Program; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 2,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 12
States / cities: Concord, New Hampshire • Derry, New Hampshire • Dover, New Hampshire + 7 more

Conditions: Smoking, Cigarette, Smoking, Tobacco, Nicotine Dependence, Exposure to Toxic Agent
Interventions: Low wattage E cigarette device, High wattage E cigarette device, Usual brand cigarette; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years to 99 Years
Enrollment: 372 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Substance Use Disorders, Hiv
Interventions: Acceptance-based Behavioral Therapy (ABBT) Intervention; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Providence, Rhode Island

Conditions: Tobacco Use Disorder
Interventions: Nicotine Patch, Sustained Release Bupropion; Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years to 45 Years
Enrollment: 594 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Alcohol Use Disorder, Alcohol Drinking, Substance Use, Drinking, Alcohol, Alcohol Use Disorder (AUD)
Interventions: Real TBS to the mPFC, Sham TBS to the mPFC; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 65 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: HIV, Mental Health, Substance Use, STI
Interventions: Automated Messaging & Monitoring, Peer Support, Coaching; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 12 Years to 24 Years
Enrollment: 1,478 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Los Angeles, California • New Orleans, Louisiana

Conditions: Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Alcohol Use Disorder, Depression
Interventions: Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy, Progressive Muscle Relaxation Training (PMRT); Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Search by objective public record fields.

Examining a New Biomarker of Nicotine Use Among Pregnant Women Who Participated in the New England SCRIPT

Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults

Cognitive Behavioral Therapy Combined With Antidepressants to Reduce HIV Risk and Drug Relapse Among Depressed Intravenous Drug Users

REAL Parenting Alcohol and Substance Use App

Enhancing Relapse Prevention for Smoking Cessation With Repetitive Transcranial Magnetic Stimulation

An Evidence-based Approach for Bullying Prevention

Comparing Two Training Methods for Opioid Wizard

Understanding and Reducing HIV Risk Behavior and Substance Use Among Self-identified Bisexual Adolescent Men

Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers

Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders

Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use

Highdose Nicotine Patch Therapy for Smokeless Tobacco Use

Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status

Improving Delay Discounting to Decrease Harsh Parenting Among Parents Receiving Substance Use Treatment

Intervention for Teens With ADHD and Substance Use

Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers

CoMBAT Opioid Use Disorder: A Combined Medication and Behavioral Activation Treatment for People Living With Opioid Use Disorder

New Hampshire Medicaid Wellness Incentive Program

Examination of Low Wattage and High Wattage E-Cigarettes

Open Trial to Improve Retention in Care for Persons With HIV Who Use Substances

Nicotine Patch and Bupropion to Reduce Smoking Rates in Younger, Low-Income, and Minority Individuals

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

Engaging Seronegative Youth to Optimize HIV Prevention Continuum

Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity