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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:59 AM EST

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Showing 313–336 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Drug Use Disorders, Hepatitis C, Harm Reduction, Opioid-use Disorder
Interventions: Community-Based, Client-Centered Prevention Home; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 343 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 6
States / cities: Appleton, Wisconsin • Eau Claire, Wisconsin • Green Bay, Wisconsin + 3 more

Conditions: Substance Withdrawal Syndrome
Interventions: Abstinence from e-cigarettes; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 147 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Alcohol Dependence, Alcohol Consumption
Interventions: Brief Intervention (adaptation of motivational interviewing); Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2006
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cannabis
Interventions: iTBS; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Substance Use, Mental Health
Interventions: Project Uplift; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Charlotte, North Carolina • Durham, North Carolina

Conditions: Drug Use, Alcohol Use, Congestive Heart Failure, Pneumonia, Acute Myocardial Infarction, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, End-Stage Renal Disease
Interventions: Specialized Community Disease Management, Treatment As Usual; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: HIV Infection
Interventions: Structured daily diary; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 24 Years · Male only
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 3
States / cities: Aurora, Colorado • Detroit, Michigan • Philadelphia, Pennsylvania

Conditions: Social Stigma, Substance Use Disorders, Mental Disorder
Interventions: Multi-level stigma reduction intervention: educational training plus controlled substance agreement policy change, Single-level stigma reduction intervention: educational training; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Nicotine Dependence
Interventions: Nicotine, behavioral counseling for smoking cessation; Drug · Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Physical Health, Mental Health, Alcohol; Use, Problem, Interpersonal Violence
Interventions: Resource pamphlet, Remote Therapy; Other · Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 25 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Nicotine Dependence
Interventions: saline, Nicotine; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 213 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Tobacco Use Disorder
Interventions: Oral tobacco, Nicotine Gum; Other · Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 70 Years
Enrollment: 391 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Eugene, Oregon

Conditions: Tobacco Dependence
Interventions: S-Adenosyl-L-Methionine, placebo; Drug · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 2
States / cities: Rochester, Minnesota • La Crosse, Wisconsin

Conditions: Mental and Behavioral Disorders Due to Use of Cocaine: Harmful Use, Opiate Addiction
Interventions: Recovery Housing plus Counseling, Usual Care Referral, Recovery Housing Only; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2008
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression, Opioid Use Disorder
Interventions: FORT-A, VA Treatment as Usual; Behavioral · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 72 Years
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Opioid Use Disorder, Loneliness, Social Isolation
Interventions: Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Alcohol Use Disorder
Interventions: Virtual Practice Facilitation with e-Learning, Virtual Practice Facilitation without e-Learning; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 89 Years
Enrollment: 399 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Nicotine Dependence
Interventions: Sleep Advancement Counseling, General Health Information; Behavioral
Lead sponsor: University of Delaware; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Tobacco Dependence
Interventions: Brief Intervention, Extended Treatment, Usual Care; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 956 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 3
States / cities: Berkeley, California • San Francisco, California • Stanford, California

Conditions: Child Behavior, Parent-Child Relations, Substance Use, Substance Abuse
Interventions: Filming Interactions to Nurture Development, The Healthy Toddler Program; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: Up to 50 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Substance Abuse
Interventions: Strengths-based case management, Case management plus facilitated treatment alliance; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 726 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Opioid Substitution Treatment Clinics, Patients, Staff
Interventions: MPACT Intervention; Other
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Substance Use
Interventions: Intervention; Behavioral
Lead sponsor: Georgia State University; Other
Eligibility: 14 Years to 18 Years
Enrollment: 123 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Tobacco Use Disorder
Interventions: Smartphone-based Financial Incentives, Best Practices; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Burlington, Vermont

Search by objective public record fields.

Community-Based, Client-Centered Prevention Homes to Address the Rural Opioid Epidemic- Aim 3

Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?

ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems

Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users

Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Feasibility of Using a Structured Daily Diary

Multi-Level Stigma Intervention for Mental Health Services

Very Low-Nicotine Cigarettes in Smokers With SUD

MVP RCT: Mind and Voice Project Randomized Control Trial

Sensitivity to Intravenous Nicotine: Genetic Moderators

Efficacy of Oral Tobacco Products Compared to a Medicinal Nicotine

S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence

Recovery Housing and Drug Abuse Treatment Outcome

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

Intervening on Opioid Use and Loneliness

Facilitating Alcohol Screening and Treatment (FAST)

Examination of Sleep, Smoking Cessation, and Cardiovascular Health

Evaluation of Tobacco Treatment Strategies for Inpatient Psychiatry

A Scaleable Video Coaching Intervention for Opioid-using Mothers

Intervention to Reduce Injection Drug Use

Pilot Study of Methadone Patient Access to Collaborative Treatment: a HEAL Initiative

Technology-Based Prevention for Adolescents in Primary Care

Smartphone-based Financial Incentives