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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Asthma, Tobacco Use
Interventions: Not listed
Lead sponsor: University of Kentucky; Other
Eligibility: 18 Years to 35 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Drug Discontinuation, Substance Use Disorders, Eating Behavior Changes, Tirzepatide
Interventions: Discontinuation and Reinitiation of Tirzepatide; Other
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Drug Abuse, Alcohol Abuse, Substance Abuse
Interventions: Random, no advanced notice drug and alcohol testing; Procedure
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 13 Years to 19 Years
Enrollment: 14,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2002
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Behavior Therapy, Cocaine, Contingency Management, Heroin Dependence, LAAM, Opioid Dependence, Substance-Related Disorders, Alcohol & Drug Use
Interventions: LAAM; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 21 Years to 55 Years
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1997 – 2001
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Substance-related Disorders
Interventions: Mindfulness Meditation, Brain and Recovery (B&R); Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Pomona, California

Conditions: Cocaine Addiction
Interventions: Vigabatrin, Matching placebo; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 45 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
Interventions: Learn to Quit-HIV, QuitGuide, Nicotine patch, Smartphone coaching; Device · Behavioral · Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder, Tobacco Smoking
Interventions: knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 16 Years to 45 Years · Female only
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Adolescent Behavior, Substance Use, Youth, Health Risk Behaviors
Interventions: iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 10 Years to 22 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance-related Disorders, HIV Risk Behavior
Interventions: Therapeutic Workplace, Methadone, Buprenorphine; Behavioral · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tobacco Use Disorder
Interventions: Web + Phone, Web Only, Phone Only, Usual Care; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 1,683 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: San Diego, California • Eugene, Oregon

Conditions: Substance Abuse, Risk Reduction, RIsky Sexual Behavior
Interventions: Handbook condition, Handbook plus condition; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 17 Years to 22 Years
Enrollment: 910 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Pullman, Washington

Conditions: Risk Reduction Through Family Therapy, Usual Care
Interventions: Risk Reduction through Family Therapy; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 17 Years
Enrollment: 135 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Nicotine Addiction, Smoking Cessation
Interventions: Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer; Drug · Other
Lead sponsor: Creighton University; Other
Eligibility: 19 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Alcohol Use Disorder, Harm Reduction, Housing First (eg. Permanent Supportive Housing)
Interventions: eHaRT-A; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 21 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Tobacco Use Disorder
Interventions: AAT experiment; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 13 Years to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Nicotine Dependence
Interventions: lorcaserin, nicotine patch, placebo lorcaserin; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Nicotine Use Disorder, Nicotine Dependence
Interventions: Active rTMS with MagVenture MagPro double blind rTMS system, Sham rTMS; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 70 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Depressive Symptoms, Substance Use
Interventions: Arrowhead Business Group Curriculum, Recreational League Control Condition; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 13 Years to 15 Years
Enrollment: 449 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Whiteriver, Arizona

Conditions: Nicotine Dependence
Interventions: GSK598809, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Addiction, Alcohol Use Disorder
Interventions: Take Control, Semaglutide; Behavioral · Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 110 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Smoking, Smoking Cessation, Craving, Addiction, Addiction Nicotine, Nicotine Dependence, Cigarette Smoking
Interventions: Real TBS to the vmPFC, Sham cTBS to the vmPFC; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Opioid-use Disorder
Interventions: Contingency Management, Brief Motivational Interviewing + Substance Free Activities + Mindfulness; Behavioral
Lead sponsor: Karen Derefinko, PhD; Other
Eligibility: 18 Years and older
Enrollment: 332 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Interventions: Centralized Virtual SBIRT; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 12 Years to 17 Years
Enrollment: 22,320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Pleasanton, California

Search by objective public record fields.

Monitoring and Outcome Measures in Asthmatics and Smokers During Pregnancy

Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation

Student Athlete Testing Using Random Notification

The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1

Women's Treatment and Early Recovery

Vigabatrin Ph 1 Cocaine Interaction Study

Learn to Quit-HIV Pilot Study

Smoking Reduction In Gravid Substance Use Disorders

Evaluating the Effectiveness of a Drug Education and Diversion Program for Middle and High School Students

Reducing Drug Use and HIV Risk in Drug-dependent Adults Arrested for Prostitution

Effectiveness of a Web-Assisted Quitline for Smokeless Tobacco Users

First Years Away From Home: Letting Go and Staying Connected

Risk Reduction for Drug Use and Sexual Revictimization

e-Cigarettes Versus NRT Gum for Smoking Cessation

Electronic Harm Reduction Treatment for Alcohol

Tobacco Approach Avoidance Training for Adolescent Smokers-1

Combination Nicotine Patch / Lorcaserin for Smoking Cessation

Accelerated rTMS for the Reduction of Nicotine Craving

Evaluation of an Entrepreneurship Program for American-Indian Youth

Effectiveness of GSK598809, a Selective D3 Antagonist, Added to CBT and NRT for Smoking Cessation and Relapse Prevention

Semaglutide Therapy for Alcohol Reduction (STAR)

QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt

SMART Trial for Buprenorphine-Naloxone Medication Assisted Treatment Adherence

Centralized Virtual SBIRT for Pediatric Primary Care