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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:23 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Substance Use, Unsafe Sexual Behavior
Interventions: Familias Unidas; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 17 Years
Enrollment: 242 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Antisocial Behavior
Interventions: Attention to Context (ATC) training, Affective Cognitive Control (ACC) training; Behavioral
Lead sponsor: The Mind Research Network; Other
Eligibility: 18 Years to 55 Years · Male only
Enrollment: 288 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Tobacco Use Disorder, Tobacco Smoking, Tobacco Dependence
Interventions: Cannabidiol (CBD) 800 mg, Placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: North Hollywood, California

Conditions: Tobacco Dependence
Interventions: Varenicline, Placebo; Drug
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
Interventions: Creating Change (CC), Seeking Safety (SS); Behavioral
Lead sponsor: VA Boston Healthcare System; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tobacco Use Disorder, Medication Adherence
Interventions: Varenicline; Drug
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Smoking Cessation, Tobacco Use Disorder
Interventions: Self-help brochure, Biomarker feedback; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 122 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Opioid Use Disorder, Treatment Adherence
Interventions: iENDURE; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Alcohol Use Disorder, Depressive Disorder, Cigarette Smoking
Interventions: Intermittent theta burst transcranial magnetic stimulation; Device
Lead sponsor: Stanford University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Palo Alto, California • Stanford, California

Conditions: Healthy, Condom Use, Mental Health, Substance Use (Drugs, Alcohol)
Interventions: NE+, Control; Behavioral
Lead sponsor: Montana State University; Other
Eligibility: 12 Years to 18 Years
Enrollment: 843 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Bozeman, Montana

Conditions: Substance Use
Interventions: Single Session Family Intervention; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 12 Years to 14 Years
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Nicotine Dependence
Interventions: Oral Nicotine Pouch, Smoking Cue Reactivity Task; Other · Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years to 55 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Drug Usage, Drug Abuse, Drug Dependence
Interventions: Standard Brief Intervention, Enhanced Brief Intervention, Control: Information and Feedback; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 589 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: HIV Infection, Alcohol Use, Bone Disease, Substance-Related Disorders
Interventions: Not listed
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: PTSD, Alcohol Use Disorder, Depression, Anxiety
Interventions: Brief Unified Protocol, Psychoeducation; Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 21 Years and older
Enrollment: 480 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Waco, Texas

Conditions: Behavior, Health
Interventions: Working Memory Training, Working Memory; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 11 Years and older
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Flint, Michigan • Highland Park, Michigan

Conditions: Tobacco Use
Interventions: Behavioral and pharmacological support to reduce combustible tobacco use.; Behavioral
Lead sponsor: Rose Research Center, LLC; Industry
Eligibility: 21 Years and older
Enrollment: 100 participants
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Tobacco Use Disorder, Cannabis Use Disorder
Interventions: Varenicline, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Nicotine Dependence, Tobacco Dependence, Cardiac Disease
Interventions: smoking reduction intervention (including NRT); Behavioral
Lead sponsor: National Institutes of Health (NIH); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2005
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tobacco Use Disorder, Smoking Cessation
Interventions: Lorcaserin Oral Tablet, Placebo oral tablet; Drug
Lead sponsor: The Mind Research Network; Other
Eligibility: 18 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Social Behavior
Interventions: Cooperative Learning; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: Not listed
Enrollment: 2,064 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions: Brief Advice, Motivational Interviewing, Behavioral Self-Control Training; Behavioral
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 75 Years
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Great Neck, New York

Conditions: Nicotine Dependence
Interventions: nicotine patch (Nicoderm Committed Quitter (CQ), Habitrol), denicotinized cigarettes (Quest 3 cigarettes); Drug · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 60 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Perinatal, Cannabis Use, Tobacco Use, Smoking Cessation
Interventions: Perinatal smoking cessation treatment and maintenance sessions; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

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Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders

Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders

Cannabidiol for Reducing Cigarette Use

Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1

Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder

Varenicline Smoking Cessation Treatment for Methadone Maintenance Patients

Promoting Home Smoking Restrictions: Biomarker Feedback to Smoking and Non-Smoking Adults

Digital Health Intervention to Support Opioid Use Disorder Treatment

Intermittent Theta Burst for the Treatment of Alcohol Use Disorders in Veterans

Nen ŨnkUmbi/EdaHiYedo Plus (We Are Here Now Plus): a Multi-level Intervention to Reduce Health Disparities Among American Indian Youth

Developing a Digital Intervention to Prevent Risky Health Behaviors

Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use

Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use

Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort

Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees

Train Your Brain 2.0 - Improving Memory and Decision Making Among Youth

Comparative Tobacco Interventions for Individuals With Severe and Persisting Behavioral Health Disorders

Varenicline for the Treatment of Cannabis and Tobacco Use Disorders in Veterans

ROSCAP: Reduction of Smoking in Cardiac Patients Study

Mechanisms of Lorcaserin for Smoking Cessation

Enlisting Peer Cooperation and Prosociality in the Service of Substance Use Prevention in Middle School

Adaptive Interventions for Problem Drinkers

Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes

Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum