Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:29 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 433–456 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Opioid-use Disorder, Chronic Pain Syndrome
Interventions: Naloxone Hydrochloride, Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Nicotine Dependence
Interventions: varenicline; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 60 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Parenting, Parent-Child Relations, Substance Use Disorders, Stress, Depression, Anxiety, Parenting Self-efficacy, Pediatrics
Interventions: Family Check-Up Online; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: Not listed
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Nicotine Dependence, Cigarettes
Interventions: Nicotine Corrective Messages; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 794 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Alcohol Abstinence
Interventions: Guanfacine XR 3mgs/daily, Placebo (for guanfacine); Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Nicotine Dependence, Depression
Interventions: exercise, health education; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Depression, Anxiety, PTSD, Suicidal Ideation, Substance Use Disorders, Unsafe Sex, Coping Behavior
Interventions: AWARE intervention; Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Boston, Massachusetts • Cambridge, Massachusetts

Conditions: Cannabis Dependence
Interventions: Exercise; Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Opioid Use Disorder, Tobacco Use Disorder
Interventions: Deep TMS System With H4 Coil; Device
Lead sponsor: Payel Roy; Other
Eligibility: 22 Years to 70 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Addiction, Substance Abuse, Cannabis Use Disorder, Cannabis Use, Cannabis Dependence, Cannabis Abuse
Interventions: Breathwork workshop; Behavioral
Lead sponsor: Elias Dakwar; Other
Eligibility: 18 Years to 70 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Parenting, Mental Health Wellness 1, Substance Use, Risky Health Behavior
Interventions: Parenting in 2 Worlds (P2W), Healthy Families in 2 Worlds (HF2W); Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 12 Years and older
Enrollment: 360 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 4
States / cities: Phoenix, Arizona • Denver, Colorado • Saint Paul, Minnesota + 1 more

Conditions: Adolescent, Depression, Substance Use Disorders
Interventions: Adolescent Coping With Depression/Functional Family Therapy; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years to 17 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Tobacco Use Disorder
Interventions: Behavioral Therapy; Behavioral
Lead sponsor: Peter Gariti; Other
Eligibility: 21 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2002
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Alcohol Abuse, Alcohol Dependence, Unhealthy Alcohol Use, Risky Alcohol Consumption Amounts, Hazardous Alcohol Use
Interventions: Brief Personalized Feedback; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 4,300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Nicotine Dependence
Interventions: Placebo, Varenicline; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 60 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: HIV Infections, Unstable Housing
Interventions: Not listed
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Substance Use, Harm Reduction, Adolescent Behavior
Interventions: iDECIDE; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 9 Years to 22 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tobacco Use Disorder, Oral Nicotine Pouch Use, Smoking Behaviors, Harm Reduction, Toxic Effect of Tobacco and Nicotine, Carcinogenesis
Interventions: ZYN; Device
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 77 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Alcohol Use Disorder, Alcohol Dependence
Interventions: Not listed
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Substance Use, Adolescent Problem Behavior
Interventions: Coalition Check-Up; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: Not listed
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Alcohol Dependence
Interventions: LPA+Fitbit, HEC; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Adolescent Behavior
Interventions: AVID Intervention; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 13 Years to 18 Years
Enrollment: 446 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Substance Use, Conduct Disorder, Depression, Anxiety
Interventions: Family Check-Up; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: Not listed
Enrollment: 593 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction, Opioid Use, Drug Use
Interventions: Collaborative Care Model; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 405 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

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The Effect of Chronic Pain on Delay Discounting in Methadone Patients

Impact of Varenicline on Blood-Oxygen-Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Activation on Smokers

Parenting Young Children in Pediatrics

Impact of Nicotine Messaging on Nicotine Beliefs and Tobacco Use Behavior

Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)

Vigorous Exercise for Depressed Smokers

AWARE Intervention: Feasibility and Efficacy Trial at Three University Health Services Centers

Interactions Between Physical Activity and Cannabis Use in Adults

Deep Transcranial Magnetic Stimulation for Tobacco Cessation in Adults With Opioid Use Disorder

Breathwork-assisted Treatment for Cannabis Use Disorder

Parenting in 2 Worlds Multisite Trial

Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD

Combining a Smoke Ending Aid With Behavioral Treatment - 1

The iHealth Study in College Students

Human Laboratory Study Of Varenicline in Smokers

Engagement in HIV Primary Care Services

A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students

Switching to Potential Reduced Exposure Products in Adult Smokers

The Impact of Heavy Alcohol Use on Saliva and Oral Health

Randomized Trial of a Data-driven Technical Assistance System for Drug Prevention Coalitions

Lifestyle Physical Activity Intervention for Depressed Alcohol Dependent Women

Randomized Trial of a Social Networks Intervention

A Family Intervention for Adolescent Problem Behavior (AKA Project Alliance 2)

Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care