Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:44 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 625–648 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Opioid Use Disorder
Interventions: Drug Cue, Money, Withdrawal, Remifentanil; Behavioral · Drug
Lead sponsor: Joshua A. Lile, Ph.D.; Other
Eligibility: 18 Years to 50 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Mental and Behavioral Disorders Due to Harmful Drug Use
Interventions: HealthCall and Motivational Interviewing, Motivational Interviewing (MI), HIV/AIDS health education; Behavioral
Lead sponsor: Research Foundation for Mental Hygiene, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: New York, New York

Conditions: Drinking, Alcohol
Interventions: TMS; Device
Lead sponsor: Auburn University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Auburn, Alabama

Conditions: Self Concept
Interventions: GirlPOWER! mentoring program, Traditional mentoring; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 10 Years to 13 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Alcohol Use Disorder
Interventions: Zonisamide, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years to 70 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Opioid-use Disorder
Interventions: DBS of the NAc; Device
Lead sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute); Other
Eligibility: 22 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2030
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Substance Use, Deliberate Self-harm, Trichotillomania, Aggression, Stealing, Eating Pathology, Gambling
Interventions: Surf the Urge; Behavioral
Lead sponsor: Kimberly N Schubert; Other
Eligibility: 14 Years to 24 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Tobacco Use Disorder
Interventions: PRIME TMS, Standard TMS; Device
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 60 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: HIV, Medication Adherence, Substance Dependence
Interventions: Spiritual Self-Schema Therapy; Behavioral
Lead sponsor: Hunter College of City University of New York; Other
Eligibility: 50 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
Interventions: Serotonergic Psychedelic, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Hamden, Connecticut • West Haven, Connecticut

Conditions: Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
Interventions: Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist; Other
Lead sponsor: Texas Christian University; Other
Eligibility: 18 Years and older
Enrollment: 1,620 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Suicide, Suicidal Ideation, Substance-Related Disorders
Interventions: Cognitive Behavioral Therapy (CBT), Supportive Psycho-education (SPC); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 3
States / cities: Colorado Springs, Colorado • Denver, Colorado • Ann Arbor, Michigan

Conditions: Cancer of Head and Neck, Breast Cancer, Prostate Cancer, Nicotine Dependence
Interventions: Transcranial Magnetic Stimulation Clinical Research System; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse, Cannabis Intoxication, Cannabis Smoking, Cannabis Withdrawal, Cannabis-Related Disorder, Cannabis Abuse, in Remission, Cannabis Abuse, Episodic Use, Marijuana, Marijuana Abuse, Marijuana Use, Marijuana Smoking, Marijuana Dependence, Marijuana User, Marijuana-Related Disorder, Marijuana Use Disorder, Addiction, Addiction, Substance, Substance Use, Substance Use Disorders, Substance Dependence, Substance Abuse, Substance Related Problem, Substance Abuse Drug Chronic
Interventions: Contingency Management, Elastic Net Regression; Behavioral · Device
Lead sponsor: Indiana University; Other
Eligibility: 14 Years to 17 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Tobacco Use, Smoking Cessation, Smoking Behaviors, Nicotine Dependence, Nicotine Withdrawal
Interventions: Nicotine Replacement Therapy (NRT) Sampling, Practice Quitting (PQ) Counseling, Motivational Interviewing (MI) Counseling; Drug · Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Tobacco Use Disorder, Dual Tobacco Use, Tobacco Dependence, Smoking, Smoking, Cigar, Smoking, Cigarette, Smoking, Tobacco
Interventions: Flavored and unflavored little cigars/cigarillos (LCCs); Other
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 34 Years
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Alcohol Use Disorder, Mild, Alcohol Use Disorder, Moderate
Interventions: Ultrabrief Behavioral Activation; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Schizophrenia, Tobacco Use Disorder, Nicotine Dependance
Interventions: Varenicline; Drug
Lead sponsor: Nathan Kline Institute for Psychiatric Research; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: New York, New York

Conditions: Nicotine Dependence, Other Tobacco Product, Tobacco Use, Smoking, Tobacco
Interventions: Treatment with JUUL 5%, Virginia Tobacco, Treatment with JUUL 5%, Cool Mint, ENDS, Treatment with JUUL 5%, Mango, ENDS, JUUL 5%, Creme Bruele, ENDS, Combustible cigarette, Smoking Cessation; Other
Lead sponsor: Juul Labs, Inc.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Depression, Substance Use
Interventions: ACT HEALTHY, Nondirective Therapy (NDT); Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 65 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • College Park, Maryland

Conditions: Sexual Assault and Rape, Risk Behavior, Alcohol Abuse
Interventions: Surveys, Interviews, Group Discussions; Other
Lead sponsor: Womack Army Medical Center; Federal
Eligibility: 18 Years to 26 Years · Male only
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Fort Bragg, North Carolina

Conditions: Tobacco Use Disorder
Interventions: Varenicline, Placebo pill; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 64 Years
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Opioid Use Disorder, Anxiety, Depression
Interventions: NEAT-O program; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Substance Use, Unprotected Sex
Interventions: AWARE; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years to 25 Years
Enrollment: 276 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 3
States / cities: Hollywood, California • Los Angeles, California • Venice Beach, California

Search by objective public record fields.

Behavioral Effects of Drugs Inpatient 44 Neurobehavioral Mechanisms of Opioid Choice

HealthCall:Brief Intervention to Reduce Non-injecting Drug Use in HIV Primary Care Clinics

Influence of TMS on Attention Modulation

Evaluation of a Youth Mentoring Program

Effectiveness of Zonisamide in Alcohol Dependent Veterans

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

Evaluation of a Brief Surf the Urge Intervention

Modulating Neural Mechanisms of Reward Processing in Tobacco Users

Intervention Targeting Substance Using Older Adults With HIV

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Justice Community Overdose Innovation Network II TCU Hub

Intervening to Reduce Suicide Risk in Veterans With Substance Use Disorders

Brain Stimulation For Cancer Smokers

Neuroimaging of Adolescent Cannabis Use Treatment

Overcoming Nicotine Dependence to Enable Quitting

Addictive Potential of LCCs in Dual Users

Ultrabrief Behavioral Activation for Reducing Alcohol Use

Varenicline Effects In Schizophrenic Smokers

Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers

Behavioral Depression Treatment for African American HIV-infected Substance Users

Piloting ProHealth: A Program for Male Soldiers on Sex, Dating and Alcohol-Use at Fort Bragg

Varenicline-Aided Cigarette Reduction in Smokers Not Ready to Quit

Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Disorders

Intervention for Substance Use and Sexual Risk Behavior in Homeless Youth