Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:38 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Posttraumatic Stress Disorder, Depression, Substance Use
Interventions: Psychological First Aid, Usual victim advocacy Services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: Charleston, South Carolina

Conditions: Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence, Risk Behavior, Homelessness
Interventions: Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU); Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 14 Years to 24 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 2
States / cities: Columbus, Ohio

Conditions: Tobacco Use, Tobacco Dependence
Interventions: Mixed-Presentation of Content; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 828 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Use Disorders, Insomnia
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I); Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alcohol Use Disorder
Interventions: Brief intervention; Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 21 Years to 55 Years
Enrollment: 164 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Posttraumatic Stress Disorder, Tobacco Dependence
Interventions: Tobacco treatment, Health Education; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Smoking Cessation, Tobacco Use Disorder
Interventions: Usual Care, Smoking Reduction; Drug · Other
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 13 Years to 19 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Nicotine Addiction, Vaping
Interventions: Nicotine pod, Placebo pod; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
Interventions: Practice Facilitation; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 13,680 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Richmond, Virginia

Conditions: Nicotine Use Disorder
Interventions: Retrieval Extinction Training (RET), Control Retrieval Extinction Training (RET); Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 25 Years to 65 Years
Enrollment: 191 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Opioid Use Disorder (OUD), Chronic Pain
Interventions: Mindfulness text messages; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Human Immunodeficiency Virus, Substance Use, Stigma, Social
Interventions: Harm Reduction; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 641 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 3
States / cities: Birmingham, Alabama • Pittsburgh, Pennsylvania

Conditions: HIV, Smoking, Tobacco Use, Nicotine Dependence
Interventions: Clinician Nudge, Patient Nudge; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: Not listed
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Use, Depression, Suicidal Ideation, Risk Behavior
Interventions: Telephone case management and motivational interviewing, Usual care; Behavioral
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 11 Years to 20 Years
Enrollment: 1,185 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Alcohol Use Disorder, Social Anxiety Disorder
Interventions: Fully integrated treatment, Stand-alone Intensive Outpatient Program; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Current Smoker, Never Smoker, Tobacco Use Disorder, Former Smoker, E-cig User
Interventions: Bronchoscopy, Electronic Cigarette, Laboratory Biomarker Analysis, Questionnaire Administration; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years to 45 Years
Enrollment: 142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Vaping, Vaping Teens, Nicotine Dependence
Interventions: QuitVaping, This is Quitting (TIQ); Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 14 Years to 19 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alcohol Abuse, Alcohol Use Disorder
Interventions: Stand-alone web-based cognitive behavioral therapy (CBT4CBT) for alcohol use disorder; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: HIV Infections, Alcohol Drinking, Substance-Related Disorders, Bone Diseases, Falls Injury, Fractures, Bone, Injuries
Interventions: Not listed
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 251 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Nicotine Dependence, Smoking Cessation
Interventions: Cognitive Behavioral Therapy, Nicotine Replacement Therapy; Behavioral · Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Tobacco Use, Tobacco Smoking, Smoking, Cigar, Smoking, Pipe, Smoking, Hookah, Nicotine Dependence
Interventions: BTI, Cigarette smoking military tailored pamphlet, Standard smoking cessation intervention; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 2,999 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Lackland Air Force Base, Texas

Conditions: Alcohol Drinking, Alcohol Use Disorder
Interventions: Video; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: San Diego, California

Conditions: Health Risk Behaviors, Risk Reduction Behavior
Interventions: Online and Text Messaging Intervention; Behavioral
Lead sponsor: University of North Texas Health Science Center; Other
Eligibility: 18 Years to 24 Years
Enrollment: 162 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Substance Use Disorder (SUD), Mental Health Disorder, Criminal Recidivism
Interventions: reentry assistance mobile health app; Behavioral
Lead sponsor: Meaningful Measurement, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Worcester, Massachusetts

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Psychological First Aid for Victims of Crime

Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness

Mixed Presentation on Social Media

Cognitive Behavioral Therapy for Insomnia in Substance Use Disorders

Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers

Tobacco Treatment as Augmentation for Cognitive Processing Therapy for PTSD

Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2

Acute Effects of Vaping Nicotine on Cognition in Young Adults

Screening and Management of Unhealthy Alcohol Use in Primary Care

Behavioral Memory Modulation in Nicotine Addiction

Opioid Adherence and Support Through Innovative Texting Strategies

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

Trial of Automated Risk Appraisal for Adolescents

Treatment for Comorbid Social Anxiety and Alcohol Use Disorders.

Effects of Electronic Cigarette Use on the Lungs

Behavioral Intervention for Youth to Promote Vaping Cessation

Integration of Neurofunctional Phenotyping Into Investigation of CBT4CBT for AUD

Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study

D-cycloserine (DCS) Pretreatment + CBT + Nicotine Replacement Therapy for Smoking Cessation (DCS)

Evaluation of a Brief Tobacco Intervention in the US Military

Alcohol Misuse Intervention in Active Duty US Navy Personnel

Enhancing Quality in Protective Strategies

Reentry Assist (R-Assist)