Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 697–720 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Nicotine Dependence
Interventions: Intravenous Nicotine; Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 40 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2015
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Alcohol Use Disorder (AUD), Suicide Ideation
Interventions: Text Message (to remind of Integrated Plan content); Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Psychotic Disorders, Substance Use
Interventions: Peer Approach to Substances in Early Psychosis Programs, Usual Care Peer Services; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 15 Years to 32 Years
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 15
States / cities: Austin, Texas • Beaumont, Texas • Big Spring, Texas + 12 more

Conditions: Hiv, Alcohol Problem
Interventions: Alcohol Brief Intervention (BI), Common Elements Treatment Approach (CETA) via Telemedicine; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 99 Years
Enrollment: 308 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Tobacco Use Disorder
Interventions: Financial incentives; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 878 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Aggression, Substance-Related Disorders
Interventions: MI-CBT, MI-CBT+CC, E-TAU; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Diagnosis, Dual (Psychiatry), Psychiatric Diagnosis, Drug Use Disorders
Interventions: Adherence Feedback (AF), AF + Contingency Management (AF + CM), AF + Motivational Enhancement Therapy (AF + MET); Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Postoperative Complications, Alcohol Use Disorder
Interventions: Blood Draw; Other
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 21 Years to 79 Years
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Obesity, Substance Abuse, Violence, Mental Health
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 11 Years to 15 Years
Enrollment: 12,651 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Alcohol Consumption, Heavy Drinker, Alcohol Use Disorder (AUD)
Interventions: Mavoglurant; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 50 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Cannabis Dependence
Interventions: MET/CBT/CM plus NRT; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Concord, New Hampshire • Lebanon, New Hampshire

Conditions: Nicotine Addiction
Interventions: Varenicline, Placebo, Transdermal Nicotine; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 1,246 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 3
States / cities: Buffalo, New York • Philadelphia, Pennsylvania • Houston, Texas

Conditions: Depression, Alcohol Abuse
Interventions: Combined Motivational Interviewing and Cognitive Behavioral Therapy, Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 24 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Opioid-Related Disorders, Drug Addiction
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 21 Years to 60 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depression, Anxiety, Alcohol Abuse, Tobacco Abuse
Interventions: Savings program; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 678 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Stanford, California

Conditions: Tobacco Use Cessation, Tobacco Use, Tobacco Smoking, Tobacco Chewing, Tobacco Dependence
Interventions: Clinic Level: AAC - SDOH, AAC - Tobacco, Non-Bundled, Bundled, Dose 1, Dose 3, Dose 6, Dose 9, Dose 12, RPN, PPN; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 1,560 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Cancer, Smoking, Tobacco Use, Nicotine Dependence
Interventions: Clinician Nudge, Patient Nudge; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: Not listed
Enrollment: 2,146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Lancaster, Pennsylvania • Philadelphia, Pennsylvania • West Chester, Pennsylvania

Conditions: Alcohol Abuse, Alcohol Abuse/addiction, Anxiety, Pain Threshold, Depression Disorders, Sleep Disorder
Interventions: AFA-281; Drug
Lead sponsor: Afasci Inc; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alcohol Use Disorder, Alcohol Drinking, Alcohol-Related Disorders
Interventions: Mindfulness-based relapse prevention, Online Mutual Support Groups; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 470 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Alcohol Use Disorder (AUD)
Interventions: Real Time Neurofeedback; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Contraceptive Usage, Contraception
Interventions: SexHealth Mobile; Behavioral
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 4
States / cities: Kansas City, Missouri

Conditions: Cannabis Dependence, Nicotine Dependence
Interventions: Cognitive Behavioral Therapy, Nicotine Replacement Therapy; Behavioral · Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Opioid Use Disorder
Interventions: BI 1356225, Placebo; Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 5
States / cities: Los Alamitos, California • Los Angeles, California • Decatur, Georgia + 2 more

Conditions: Smoking
Interventions: Breath Sample, Saliva Sample, Questionnaire, View Virtual Reality Scenes; Other · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Search by objective public record fields.

IV Nicotine Induced Changes in Hormone Function, Mood States and Behavior

A MRT to Optimize a JITAI for Alcohol Craving and Suicide Ideation

Peer Approaches to Substances in Early Psychosis Programs: A Pilot Study of a Peer-Led Intervention

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

Financial Incentives for Smoking Cessation

Preventing Violence Among Veterans in Substance Use Disorder Treatment

Increasing Treatment Adherence in Co-Occurring Psychiatric and Drug Use Disorders

Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC

Health Behaviors in School-age Children: 2009-2010

Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers

Targeting Tobacco Cessation During Treatment for Cannabis Use Disorders

Pharmacogenetics of Nicotine Addiction Treatment

Therapy for Undergraduate College Students Who Binge Drink and Are Depressed

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

The EARN-Health Trial of Financial Savings and Health

Reach Through Equitable Implementation in Utah

Improving Tobacco Treatment Rates for Outpatient Cancer Patients Who Smoke

A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder

TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study

Brain Network Modulation and Alcohol Use

SexHealth Mobile: Integrating a Mobile Clinic and a Point-of-care Contraception Counseling and Access

Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence

A Study to Test Whether BI 1356225 Improves Impulsive Behavior in People With Opioid Use Disorder Who Are Taking Buprenorphine

Cue Reactivity in Virtual Reality: The Role of Context