Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:15 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 721–744 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Tobacco Use Disorder
Interventions: Bupropion, Placebo, weight concerns intervention, smoking cessation intervention; Drug · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 349 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Schizophrenia, Tobacco Use Disorder
Interventions: 300 mg/day bupropion-sr, 0 mg/day bupropion-sr; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2006
U.S. locations: 2
States / cities: Providence, Rhode Island

Conditions: Substance Use Disorder
Interventions: Mindful Awareness in Body-oriented Therapy, Womens Health Education; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 217 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Smoking Cessation, Nicotine Dependence
Interventions: NicoBloc, Nicotine Lozenge; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Tobacco Use Disorder
Interventions: Usual Care, Individual Rewards, Fixed Deposits, Competitive Deposits (Pari-Mutuel), Collaborative Rewards; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 2,185 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Opioid-use Disorder, Acceptability of Health Care, Opioid-Related Disorders
Interventions: Not listed
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years and older
Enrollment: 817 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions: Full Motivational Interviewing ("FMI"), Spirit Only Motivational Interviewing ("SOMI"); Behavioral
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Great Neck, New York

Conditions: Counseling
Interventions: Recovery Guide Counseling; Behavioral
Lead sponsor: Howard University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Depression, Substance Use Disorder, Anxiety
Interventions: Virtual Behavioral Health Integration; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 5,777 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 20
States / cities: Albemarle, North Carolina • Charlotte, North Carolina • Concord, North Carolina + 13 more

Conditions: Opioid Use, Opioid-use Disorder, Risk Reduction, Hiv
Interventions: Suboxone, PrEP; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Charlotte, North Carolina • Durham, North Carolina • Wilmington, North Carolina

Conditions: Substance-Related Disorders, Opioid-Related Disorders, Behavior Therapy
Interventions: App + Inputs Contingency Management, App + Outcomes Contingency Management; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Berkeley, California • Chicago, Illinois • Wauwatosa, Wisconsin

Conditions: Alcohol Use Disorder
Interventions: Control, Functional Analysis, Cognitive Restructuring, Dealing With Cravings; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Tobacco Use Disorder
Interventions: Persistence Targeted Smoking Cessation, Clearing The Air, Nicotine lozenge; Behavioral · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 64 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Smoking Cessation, Smoking Behaviors
Interventions: Tirzepatide, Placebo; Drug · Other
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years to 65 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 4
States / cities: Los Angeles, California • Aurora, Colorado • New Haven, Connecticut + 1 more

Conditions: Alcohol Drinking, Marijuana Smoking
Interventions: brief counseling; Behavioral
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 18 Years and older
Enrollment: 554 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Tobacco Smoking, Alcohol-Related Disorders
Interventions: MINDSET, Usual Care; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Smoking Cessation
Interventions: Group Counseling, Individual Counseling, Phone Counseling, Video Counseling, Texting support, Nicotine Replacement Therapy; Behavioral · Drug
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Heavy Drinking, Alcohol Drinking, Substance Use, Drinking Behavior
Interventions: Standard Brief Intervention, Trauma-Informed and Peer-Supported Brief Intervention, Assessment only; Behavioral
Lead sponsor: Western Kentucky University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 284 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Bowling Green, Kentucky

Conditions: Alcohol Drinking, Tobacco Smoking
Interventions: Media Detective; Behavioral
Lead sponsor: Innovation Research & Training; Other
Eligibility: 7 Years to 12 Years
Enrollment: 679 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Nicotine Dependence
Interventions: Sit to Quit, Quit for Life; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Substance Use, Stress, Relation, Interpersonal, Bullying, Victimisation, Mental Health Issue, Sleep, Inadequate, Social Skills
Interventions: PeerLearning.net; Behavioral
Lead sponsor: Oregon Research Behavioral Intervention Strategies, Inc.; Industry
Eligibility: Not listed
Enrollment: 924 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Acquired Immunodeficiency Syndrome
Interventions: Not listed
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 12 Years to 24 Years
Enrollment: 513 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 5
States / cities: Aurora, Colorado • Baltimore, Maryland • Boston, Massachusetts + 2 more

Conditions: Smoking, Nicotine Dependence
Interventions: Placebo, St. John's Wort-900 mg/day, St. John's Wort-1800mg/day; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Tobacco Use Cessation, Sleep Disorders
Interventions: Bupropion, Transdermal Nicotine Patch, Placebo Bupropion, Placebo transdermal nicotine patch; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Menlo Park, California

Search by objective public record fields.

Bupropion and Weight Control for Smoking Cessation - 1

Effect of Bupropion on Smoking Behavior in Smokers With Schizophrenia

Body-oriented Therapy for Women in SUD Treatment

Comparing NicoBloc to Nicotine Lozenges

Way to Quit - Comparative Efficacy, Acceptance and Effectiveness of Health Incentive Structures

Patients' Attitudes Toward and Experiences With Buprenorphine Treatment

Component Analysis for Motivational Interviewing

Improving Treatment and Recovery Services for Individuals With Opioid Problems

Virtual Behavioral Health Integration

Providing Suboxone and PrEP Using Telemedicine

Incentives to Decrease Opioid Use - Pilot

Effect of CBT Microinterventions on Mechanisms of Behavior Change Among Adults With AUD

Persistence-Targeted Smoking Cessation

Multi-Site Trial of Tirzepatide for Smoking Cessation

Brief Counseling to Reduce Injuries Among Emergency Department Patients Who Report Alcohol and Substance Use

Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease

End Nicotine Dependence Clinic

A Brief Intervention for Alcohol Users With Interpersonal Trauma

Evaluation of the Media Detective Program for Elementary School-Aged Children to Prevention Substance Use

Study on Sit to Quit Phone Intervention

Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School

Managerial Database II

St. John's Wort for Tobacco Cessation

Impact of Smoking Cessation on Sleep - 5