Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:47 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 817–840 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Tobacco Dependence
Interventions: Standard, Deep Cultural; Behavioral
Lead sponsor: University of Massachusetts, Boston; Other
Eligibility: 18 Years and older
Enrollment: 109 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
Interventions: Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT); Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Substance Use Disorders
Interventions: Aroma Inhaler with Bergamot essential oil; Other
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Breast Cancer, Tobacco Dependence
Interventions: placebo, varenicline; Drug
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Addiction Nicotine
Interventions: VapeAway filter system; Device
Lead sponsor: VapeAway; Industry
Eligibility: 21 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcohol Use Disorder
Interventions: Online survey; Other
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 18 Years and older
Enrollment: 733 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Smoking, Acute Coronary Syndrome
Interventions: Varenicline 100 mg by mouth twice daily, control; Drug
Lead sponsor: Newark Beth Israel Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2008
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Nicotine Vaping, Nicotine Use Disorder
Interventions: quitSTART Mobile Application, Chatbot Feature in quitSTART Mobile Application; Device · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 15 Years to 25 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Addiction
Interventions: Screening Only (SO) condition, SUSIT Condition; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Tobacco Use Disorder, Schizophrenia, Schizoaffective Disorder
Interventions: Persistence Targeted Smoking Cessation in SMI (PTSC-S), Nicotine patch; Behavioral · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 70 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Tobacco Use Disorder, Smoking
Interventions: Ariva® Silver Wintergreen, Silver Wintergreen; Other
Lead sponsor: Star Scientific, Inc; Industry
Eligibility: 23 Years to 72 Years
Enrollment: 111 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Martinsburg, West Virginia

Conditions: Attention Deficit Hyperactivity Disorder, Substance Abuse
Interventions: Atomoxetine, Placebo; Drug
Lead sponsor: Denver Health and Hospital Authority; Other
Eligibility: 12 Years to 19 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Opioid-Related Disorders, NAS, Substance Use Disorders, Mental Health
Interventions: Observational Study; Other
Lead sponsor: Trustees of Dartmouth College; Other
Eligibility: 16 Years to 50 Years · Female only
Enrollment: 2,510 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 10
States / cities: Augusta, Maine • Bangor, Maine • Keene, New Hampshire + 6 more

Conditions: Heavy Drinking, Alcohol Drinking, Substance Use, Drinking Behavior
Interventions: Standard Brief Intervention, Trauma-Informed and Peer-Supported Brief Intervention; Behavioral
Lead sponsor: Western Kentucky University; Other
Eligibility: 18 Years to 29 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Bowling Green, Kentucky

Conditions: Attention Deficit Hyperactivity Disorder, Nicotine Dependence
Interventions: Transdermal Nicotine Patch, Lis-dexamphetamine (Vyvanse), Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cardiovascular Disease, Tobacco Use Disorder
Interventions: Nicotine replacement, Motivational counseling; Drug · Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 2
States / cities: Minneapolis, Minnesota

Conditions: Substance Use, Substance Use Disorders, Substance Dependence, Veterans
Interventions: VetReach; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Substance Use Disorders, Treatment Refusal
Interventions: Group Community Reinforcement Training for Parents, Individual Community Reinforcement Training for Parents; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: Not listed
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Contraceptive Usage, Opioid Dependence
Interventions: Contraceptive management program, Usual care; Behavioral · Other
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Behavioral Health
Interventions: Episodic Future Thinking; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: Female only
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Nicotine Addiction, Drug Addiction, Drug Dependence, Substance Use Disorder, Tobacco Dependence
Interventions: Treatment A with device Clickotine® (Active intervention), Treatment B with smoking education (control); Device
Lead sponsor: Click Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Use Disorders
Interventions: Mindfulness Based Relapse Prevention, Relapse Prevention, Treatment as Usual; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 70 Years
Enrollment: 286 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Nicotine Dependence
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 64 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Use (Drugs, Alcohol), Tobacco Use, Adolescent Substance Use
Interventions: Integrated Community Engagement Collaborative, School-Based Data Collection and Reporting without Network Coordinator Support; Other
Lead sponsor: West Virginia University; Other
Eligibility: 10 Years and older
Enrollment: 25,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Morgantown, West Virginia

Search by objective public record fields.

Tobacco Dependence Treatment for Asian Americans

Virtual Incentive Treatment for Alcohol

Using Aromatherapy in Substance Use Disorder

Tobacco Dependence in Breast Cancer Patients Trial of Varenicline (Chantix)

The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction

Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse

Safety and Efficacy of the Novel Selective Nicotinic Receptor Partial Agonist, CHANTIX (Varenicline) in Patients With Acute Coronary Syndrome

Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

Leveraging Technology to Address Unhealthy Drug Use in Primary Care Settings

Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI)

Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers

Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder

MOms in REcovery (MORE) Study: Defining Optimal Care

A Brief Intervention for Young Adult Substance Users With Interpersonal Trauma

Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study

Reduction of Smoking in Cardiac Disease Patients

Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders

Individual vs. Group Community Reinforcement Training to Help Parents of Substance-using Treatment-refusing Youth

Improving Effective Contraceptive Use Among Opioid-maintained Women

Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes

Clinical Trial of an Innovative Digital Therapeutic for Smoking Cessation With Biochemical Verification

Mindfulness Based Relapse Prevention: Efficacy and Mechanisms

Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers

The ICEC Cluster Trial: Integrated Community Engagement Collaborative for Youth Substance Use Prevention in Rural America