Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 10:06 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 865–888 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Alcohol Use Disorder
Interventions: Brief phone aftercare intervention, individual aftercare therapy; Behavioral
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 13 Years to 18 Years
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: HIV Infections, Stigma, Social
Interventions: Standard of care engagement practices, Peer Navigators Addressing INtersectional Stigma to Improve HIV Prevention Among Criminal-Justice Involved Women; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 49 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR)
Interventions: Alcohol; Drug
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 30 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Opioid Use Disorder, Chronic Pain
Interventions: CBT4CBT COPES; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: Bridgeport, Connecticut • Danbury, Connecticut • Waterbury, Connecticut

Conditions: Alcohol Drinking, Drug Abuse, HIV
Interventions: Motivational Network Interview; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Los Angeles, California • Santa Monica, California

Conditions: Tobacco Use Disorder
Interventions: Self-determination Intervention for Tobacco Dependence; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 837 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Alcohol Use Disorder
Interventions: High-density transcranial alternating current stimulation, Sham stimulation, Motivational interviewing; Device · Behavioral
Lead sponsor: The Mind Research Network; Other
Eligibility: 21 Years to 60 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Opioid Use Disorder
Interventions: Psilocybin; Drug
Lead sponsor: Anna Rose Childress, Ph.D.; Other
Eligibility: 18 Years to 60 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
Interventions: Participatory System Dynamics (PSD), Audit and Feedback (AF); Other
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 18 Years and older
Enrollment: 720 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Opioid Use, Traumatic Injury, Adolescent Behavior, Substance Abuse Disorder
Interventions: Not listed
Lead sponsor: Indiana University; Other
Eligibility: 12 Years to 20 Years
Enrollment: 123 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Craving, Self Efficacy, Affective; Reaction, Substance Abuse
Interventions: CARESS, Isometric Exercise; Behavioral
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Fairfax, Virginia

Conditions: Smoking Cessation, Nicotine Addiction, Schizophrenia
Interventions: Active TMS stimulation, Sham TMS stimulation; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 60 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Use, Substance Abuse, Suicide
Interventions: Thiwáhe Gluwáš'akapi, Woyute Waśte; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 10 Years to 85 Years
Enrollment: 552 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Tobacco Dependence
Interventions: nicotine lozenges, tobacco-free snuff; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: Rochester, Minnesota • Eugene, Oregon

Conditions: Opioid-use Disorder
Interventions: Psychosocial support determined by adaptive treatment algorithm; Behavioral
Lead sponsor: Public Health Management Corporation; Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Alcohol Drinking, Alcohol-Related Disorders, Disease, Inflammation, Alcoholism, Cognitive Dysfunction, Pathologic Processes, Drinking Behavior, Substance-Related Disorders, Chemically-Induced Disorders, Mental Disorder, Cognition Disorder, Neurocognitive Disorders, Minocycline, Anti-Bacterial Agents, Anti-Infective Agents
Interventions: Minocycline, Sugar pill; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 25 Years to 65 Years
Enrollment: 142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Catonsville, Maryland

Conditions: Opioid Use Disorder, Opioid Use, Insomnia, Orexin Antagonist
Interventions: Placebo, Lemborexant 10 MG; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking, Smoking Cessation, Tobacco Use Cessation
Interventions: Usual Care, "Nudges"; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Alcohol Use Disorder
Interventions: gabapentin enacarbil, Placebo; Drug
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 21 Years and older
Enrollment: 346 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 10
States / cities: Los Angeles, California • San Francisco, California • Miami, Florida + 7 more

Conditions: Nicotine Dependence, Smoking, Cigarette, Smoking Cessation, Smoking Behaviors, Smoking Reduction, Craving
Interventions: Isradipine, Cue Exposure; Drug · Behavioral
Lead sponsor: Jasper A. Smits; Other
Eligibility: 18 Years to 65 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Opioid Dependence, Injection Drug Use
Interventions: Community-based buprenorphine treatment (CBBT) intervention; Behavioral
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
Interventions: Mindfulness Based Relapse Prevention, Control (CTL); Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 26 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Tobacco Dependence
Interventions: SWITCH IT, E-cig Provision Only; Behavioral · Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Louisville, Kentucky • Providence, Rhode Island

Conditions: ADHD, Substance Use Disorders
Interventions: Medication Integration Protocol (MIP), Changing Academic Support in the Home for Adolescents with ADHD (CASH-AA); Behavioral
Lead sponsor: The National Center on Addiction and Substance Abuse at Columbia University; Other
Eligibility: 12 Years to 18 Years
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Aftercare for Adolescents Treated for Alcohol Abuse and Dependence

HIV Prevention Peer Navigation for Justice Involved Women

Impulsivity and Alcohol Response

Computer Based Treatment for Cognitive Behavioral Therapy and Cooperative Pain Education and Self-Management

Enhancing Housing First Programs With a Social Network Substance Use Intervention

Smokers' Health Project: Self-Determination and Maintaining Tobacco Abstinence

A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol

Wellcome Leap Psilocybin for OUD

Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care

Opioid Use After Traumatic Injury in Adolescents

CARESS: An Investigation of Effects of CARESS

Circuitry-Guided Smoking Cessation in Schizophrenia

Evaluation of Thiwáhe Gluwáš'Akapi Substance Use Prevention Program

Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction

Examining an Adaptive Approach to Providing Psychosocial Support to Buprenorphine Patients

Neuroimmune Dysfunction in Alcohol Use Disorder

Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects

Implementation Science to Reduce the Disparity in Tobacco Treatment Among Individuals With Serious Mental Illness

HORIZANT (Gabapentin Enacarbil Extended-Release Tablets) for the Treatment of Alcohol Use Disorder

Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation

Pilot Test of a Community-based Buprenorphine Treatment Intervention

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

Harm Reduction for Smokers With Mental Illness

Integrated Treatment for Adolescents With ADHD