Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:57 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 889–912 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Alcohol Use Disorder
Interventions: Scarcity Narrative, Neutral Narrative; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Intimate Partner Violence, Substance Use
Interventions: Standard Care, Brief Alcohol Intervention combined with standard care; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: Female only
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking, Nicotine Dependence
Interventions: Telephone quitline; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Tobacco Dependence, Withdrawal Symptoms, Smoking Cessation
Interventions: 1.0mg Varenicline b.i.d., 0.5mg Varenicline b.i.d., 0.0mg placebo Varenicline b.i.d.; Drug
Lead sponsor: Arizona State University; Other
Eligibility: 21 Years and older
Enrollment: 313 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 2
States / cities: Phoenix, Arizona • Burbank, California

Conditions: Drug Use, Alcohol Use
Interventions: SBIRT+; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 3
States / cities: Philadelphia, Pennsylvania

Conditions: Nicotine Dependence
Interventions: placebo, Galantamine 8mg, Galantamine 16mg; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
Interventions: Care Navigation; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Alcohol Use Disorder, Depression
Interventions: Internet-Delivered Brief Intervention; Other
Lead sponsor: Cornell University; Other
Eligibility: 18 Years to 62 Years
Enrollment: 450 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: HIV, Opioid Dependence
Interventions: Community-friendly Health Recovery Program, Time-and-Attention-Matched Control Condition; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: PTSD, Depression, Substance Use Disorder, Traumatic Brain Injury
Interventions: WEB-ED+ Treatment Arm; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 1,312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Smoking, Nicotine Dependence
Interventions: Bupropion; Drug
Lead sponsor: Henry Kranzler; Other
Eligibility: 18 Years and older · Female only
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 3
States / cities: Newark, Delaware • Philadelphia, Pennsylvania

Conditions: Substance Use Disorder, Alcohol Use Disorder
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 99 Years
Enrollment: 10,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2047
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Use, HIV/AIDS, Older Adults, Behavioral Intervention, Infectious Disease
Interventions: Psycho-educational content (5 Minutes), Readiness Assessment (10 minutes), Goal-Setting (5 minutes), Identifying and prioritizing needs (5 minutes), Explanation of Peer Navigator and Session wrap (5 minutes); Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 3
States / cities: Gainesville, Florida • Jacksonville, Florida • Lake City, Florida

Conditions: HIV, Mental Health, Illicit Substance Use, Sexually Transmitted Infections (STI)
Interventions: Level 1, Level 2, Level 3; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 12 Years to 24 Years
Enrollment: 170 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Los Angeles, California • New Orleans, Louisiana

Conditions: Alcohol Drinking, Marijuana Smoking
Interventions: MI/CBT, RT/SU; Behavioral
Lead sponsor: University of Rhode Island; Other
Eligibility: 14 Years to 19 Years
Enrollment: 205 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: Cranston, Rhode Island

Conditions: Opioid Use Disorder, Substance Use Disorders, Medication Assisted Treatment
Interventions: Minds and Mentors, Twelve Step Intervention Group; Behavioral
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 19 Years and older
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 4
States / cities: Birmingham, Alabama • Tuscaloosa, Alabama

Conditions: Tobacco Use Disorder
Interventions: AZD8529; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 214 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 9
States / cities: Encino, California • La Jolla, California • Los Alamitos, California + 6 more

Conditions: Character, Violence, Substance Use, Pro-social Behavior, Academic Achievement
Interventions: Positive Action; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 6 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2006
U.S. locations: 3
States / cities: Twin Falls, Idaho • Chicago, Illinois • Corvallis, Oregon

Conditions: Alcohol Use Disorder, Insomnia
Interventions: Web-Based Insomnia Education Program, SHUTi Intervention; Behavioral
Lead sponsor: Jessica Weafer; Other
Eligibility: 21 Years to 50 Years
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Hypertension, Substance Abuse, Asthma, Depression
Interventions: Primary care redesign; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 816 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 10
States / cities: Birmingham, Alabama • Martinez, California • San Francisco, California + 6 more

Conditions: Nicotine Dependence, Smoking Cessation
Interventions: Varenicline and smoking cessation counseling, Exercise or relaxation treatment; Other · Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 45 Years and older · Female only
Enrollment: 301 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2017
U.S. locations: 2
States / cities: Farmington, Connecticut • Minneapolis, Minnesota

Conditions: Problem Drinking, Aggression, Stress, Psychological
Interventions: Mindfulness-Based Resilience Training (MBRT); Behavioral
Lead sponsor: Pacific University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Forest Grove, Oregon

Conditions: Nicotine Dependence, Alcohol Use
Interventions: Mindfulness Training for Smokers, Interactive Learning for Smokers; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 29 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation, Smoking (Tobacco) Addiction
Interventions: Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham, Nicotine Cessation Counseling, D-cycloserine; Drug · Device · Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Decreasing the Temporal Window in Individuals With Alcohol Use Disorder

Brief Intervention to Reduce Drinking and Intimate Partner Violence in Women

A Brief Dental Office Intervention With Tobacco Quitline

Varenicline OTC Trial on Efficacy and Safety

Integrating Substance Abuse Assessment & Intervention in Primary Care Settings

A Study to Help People Quit Smoking.

Addressing Barriers to Care for Substance Use Disorder Pilot Study

The Network Study: Soldiers Connecting for Work and Health

Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users

Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care

Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant Women

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Feasibility of SBIRT-PN

Stepped Care for Youth Living With HIV

Motivation and Skills for Delta-9-tetrahydrocannabinol/Ethanol (THC/ETOH+) Teens in Jail

Minds and Mentors Program- R33

The Study of AZD8529 for Smoking Cessation in Female Smokers

Randomized Trial of the Positive Action Program in Hawaii Schools

Testing an Online Insomnia Intervention

Linking Former Inmates to Primary Care

Exercise or Relaxation for Smoking Cessation

Feasibility and Acceptability of Mindfulness-based Resilience Training for Rural Law Enforcement Officers

Pilot Study on Mindfulness for Tobacco and Alcohol in University Students

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)