Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:25 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 961–984 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Smoking Cessation
Interventions: Cognitive behavioral, Control; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain, Insomnia, Depression, Anxiety
Interventions: Medical Marijuana; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 269 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Opioid-use Disorder, Suicidal Ideation
Interventions: Buprenorphine/Naloxone 8/2 milligram (mg) Sublingual Film, Morphine Sulfate 30 mg; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Cannabis-use Disorders
Interventions: Pregabalin, Placebo; Drug
Lead sponsor: Joshua A. Lile, Ph.D.; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Substance Use
Interventions: neurocognitive tasks; Other
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 18 Years and older
Enrollment: 117 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2029
U.S. locations: 2
States / cities: Blacksburg, Virginia • Roanoke, Virginia

Conditions: Alcohol Abuse, Alcohol Drinking
Interventions: Counselor-administered Brief Motivational Intervention (BMI), Alcohol 101 Plus (interactive CD-ROM), AlcoholEdu (Internet-based tutorial); Behavioral
Lead sponsor: Syracuse University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 703 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Tobacco Use
Interventions: THC; Drug
Lead sponsor: Battelle Memorial Institute; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Nicotine Dependence
Interventions: nicotine, menthol; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 57 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: West Haven, Connecticut

Conditions: Nicotine Dependence, Other Tobacco Product
Interventions: Nicotine, Low Dose Menthol, High Dose Menthol; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 20 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking, Nicotine Dependence, Electronic Health Records, Translational Research
Interventions: EHR Enhanced Clinic Intervention; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: Not listed
Enrollment: 28,095 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse, Diet Modification, Health Behavior, Health Knowledge, Attitudes, Practice, Relationship, Family, Relation, Parent-Child, Emotional Stress
Interventions: Weaving Healthy Families Program; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 5 Years to 120 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Alcohol Use Disorder
Interventions: Lacosamide, Placebo oral capsule; Drug
Lead sponsor: Boston Medical Center; Other
Eligibility: 21 Years to 55 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alcoholism
Interventions: Topiramate and N-Acetyl Cysteine, Topiramate and Placebo; Drug
Lead sponsor: Nassima Ait-Daoud Tiouririne; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Adherence, HIV Risk Behaviors, Alcohol & Drug Use, Health Behaviors, Sexual Risk Behaviors
Interventions: Motivational interviewing; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 16 Years to 24 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Hiv
Interventions: Collaborative drug therapy management model, Cabotegravir/Rilpivirine; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Opioid Use Disorder
Interventions: OUD Telehealth Platform; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking Cessation
Interventions: Stepped-Care, Control; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Walnut Creek, California

Conditions: Substance Use Disorders, Depression, Anxiety, Emotional Disorder, Suicidal Ideation, Suicidal and Self-injurious Behavior
Interventions: Unified Protocol (UP), Treatment as Usual (TAU); Behavioral · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 26 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance-Related Disorders
Interventions: Rotigotine Transdermal System [Neupro], Placebo; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 25 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Stigma, Co-Occurring Disorders, Substance Use Disorder, Mental Health Disorder, Veterans
Interventions: Veterans Affairs-Honest, Open, Proud; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Bedford, Massachusetts

Conditions: Alcohol Use Disorder
Interventions: Placebo, Alcohol; Drug
Lead sponsor: Jessica Weafer; Other
Eligibility: 21 Years to 25 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Boston, Massachusetts • Columbus, Ohio

Conditions: Tobacco Use Disorder
Interventions: Behavioral and pharmacologic tobacco use intervention; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Persistent Depressive Disorder
Interventions: Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch, Smartphone coaching, Nicotine gum, Nicotine Lozenges; Device · Behavioral · Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 343 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 3
States / cities: Buffalo, New York • Durham, North Carolina • Winston-Salem, North Carolina

Conditions: Substance-Related Disorders
Interventions: D-cycloserine, Placebo; Drug
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years to 70 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Cognitive Behavioral Smoking Cessation Intervention for Adults With Chronic Pain

Effect of Medical Marijuana on Neurocognition and Escalation of Use

Anti-suicidal Effects of Buprenorphine in Opioid Use Disorder

Behavioral Effects of Pregabalin and Cannabis

Neurocognitive Predictors of Health Risk Behaviors

Substance Use Risk Education (SURE) Project

A Laboratory Model of Increasing Delta-9-tetrahydrocannabinol (THC) Potency on Cigarette Smoking

The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

Project 1: Evaluating EHR-Based Health System Modifications for the Chronic Care of Smoking

The Weaving Healthy Families Program

Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers

Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder

The Aim of This Study is to Determine the Effectiveness of a Motivational Enhancement Intervention in Reducing Risk Behaviors (Drug and Alcohol Use, Sexual Risk Behavior, Poor Adherence to Medications) Among HIV+ Youth. - 1

Pharmacist-led Intervention for Injectable HIV Treatment for Women With Health-related Social Needs

Telehealth Treatment for Opioid Use Disorders

Interventions for Smoking Among Persons in Recovery

Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders

Transdermal Rotigotine as Adjunct to Behavioral Therapy for Cocaine Use Disorder

Honest, Open, Proud (HOP): A Peer Delivered, Co-occurring Disorders Intervention for Justice-involved Veterans

Impulsivity Domains and Subjective Response

Tobacco Use Intervention Among Radiation Oncology Patients

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings

Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use