Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:00 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1057–1080 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Alcohol Use Disorder, Alcohol Drinking
Interventions: Pitolisant, Placebo; Drug
Lead sponsor: Boston Medical Center; Other
Eligibility: 21 Years to 55 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tobacco Cessation, Tobacco Abstinence, Tobacco Use, Tobacco Use Cessation, Tobacco Dependence
Interventions: Nicotine Replacement Therapy (NRT), Wellness Coaching; Drug · Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression, Opioid-use Disorder, Opioid Abuse
Interventions: Ketamine Hydrochloride, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Tobacco Use Disorder, Nicotine Dependence
Interventions: Counseling, Contingency management, Text-based support; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 25 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Adolescent Substance Use
Interventions: Not listed
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 12 Years to 18 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Opioid Withdrawal, Opioid Use Disorder (OUD)
Interventions: Sparrow Link (Active tAN), Sparrow Link (Sham tAN); Device
Lead sponsor: Payel Roy; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Tobacco Use Cessation, Tobacco Use Disorder
Interventions: 10-week smoking cessation group therapy combined with NicoDerm CQ; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: HIV/AIDS, Substance Use Disorders, Adherence, Medication
Interventions: Digital pill, Truvada; Device · Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older · Male only
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Boylston, Massachusetts

Conditions: Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions: Adaptive Tailored Intervention, Consequence-based Intervention, Tailored, not adaptive, based Intervention, Assessment only; Behavioral · Other
Lead sponsor: Northwell Health; Other
Eligibility: 21 Years to 65 Years
Enrollment: 174 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Great Neck, New York

Conditions: Tobacco Use Cessation
Interventions: Not listed
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 238 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Tobacco Dependence
Interventions: Innovative System, Standard Treatment Control (STC); Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 175 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Substance Use, Sexual Behavior
Interventions: Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (TODOS), Control condition - 3 Monthly Group Activities in the Community; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 8 Years and older · Female only
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Whiteriver, Arizona

Conditions: Alcohol Use Disorder
Interventions: Mobile health application, Medical Management; Other
Lead sponsor: Quit Genius; Industry
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Use
Interventions: Behavior Therapy; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 60 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2004
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: PTSD
Interventions: Cognitive Processing Therapy, STAIR Narrative Therapy; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Palo Alto, California • San Francisco, California

Conditions: Sex Trafficking, HIV, Substance Use (Drugs, Alcohol), Mental Health, Sexual Violence, Treatment Engagement
Interventions: CONNECT; Behavioral
Lead sponsor: Lifespan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Cigarette Smoking, Nicotine Dependence
Interventions: Receipt of Genetic Results, No results given; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Substance Use (Drugs, Alcohol), Health Risk Behaviors, Youth, Adolescent Behavior
Interventions: iDECIDE; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: Not listed
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stigma, Social, Opioid Use, Opioid-use Disorder, Substance Use Disorders
Interventions: Intrapersonal Stigma Reduction, Interpersonal Stigma Reduction; Other
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Second Hand Tobacco Smoke, Nicotine Dependence
Interventions: Clinic Quality Improvement + Behavioral Counseling, Clinic Quality Improvement + Attention Control; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years and older
Enrollment: 327 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 4
States / cities: Philadelphia, Pennsylvania

Conditions: Pregnancy
Interventions: HIP; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 410 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 5
States / cities: Oakland, California • San Francisco, California • San Jose, California

Conditions: Current Smoker, Former Smoker, Multiple Pulmonary Nodules, Tobacco Use Disorder
Interventions: Aspirin, Laboratory Biomarker Analysis, Placebo; Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 50 Years and older
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Marijuana Abuse
Interventions: MET/CBT, CM, BPT; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 12 Years to 18 Years
Enrollment: 153 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Alcohol Drinking, Alcohol Use Disorder (AUD), Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
Interventions: Alcohol beverage, Control - non alcoholic beverage; Drug · Other
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 21 Years to 30 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Champaign, Illinois

Search by objective public record fields.

Pitolisant Effects on Alcohol Self-Administration in Heavy Drinkers

Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

Ketamine for the Treatment of Opioid Use Disorder and Depression

Young Adult Tobacco/Nicotine and Cannabis Co-use

The Neuroeconomics of Behavioral Therapies for Adolescent Substance Abuse

Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

Smoking Treatment of Prisoners

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

Tailored Mobile Text Messaging to Reduce Problem Drinking

Natural History of Attempts to Stop Smoking

Tobacco Intervention in Buprenorphine Treatment

Telling Our Daughters Our Story

Integrated Digital Intervention for Alcohol Use Disorder

Early Tobacco Abstinence - 5

A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

Digital Intervention Delivered Via Street Medicine to Increase HIV and Substance Use Care Among Survivors of Sex Trafficking

Smokers' Response to Nicotine Dependence Genotyping

Pilot of a Drug Education Curriculum for Middle and High School Students

SMART Trial: Intrapersonal and Interpersonal Stigma Reduction

Kids Safe and Smokefree (KiSS)

The Health in Pregnancy (HIP) Study

Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules

Treatment for Adolescent Marijuana Abuse

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design