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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:24 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1129–1152 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette, Smoking, Pipe, Smoking (Tobacco) Addiction, Smoking, Tobacco Use, Tobacco Dependence, Tobacco Use Cessation, Tobacco Smoking, Tobacco; Use, Rehabilitation, Nicotine Dependence, Nicotine Use Disorder, Nicotine Dependence, Cigarettes, Nicotine Dependence Tobacco Product
Interventions: Specialized Quitline, Basic Needs Navigator; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 1,944 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Nicotine Dependence
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS); Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2030
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Substance Use Disorders, Treatment Adherence and Compliance
Interventions: KATR Linkage Strategy; Behavioral
Lead sponsor: Terry Bunn; Other
Eligibility: 18 Years and older
Enrollment: 458 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Berea, Kentucky • Lexington, Kentucky

Conditions: Opioid Use Disorder, Chronic Pain
Interventions: Steps 2 Change (S2C), Control; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Cannabis Use Disorder, Tobacco Use Disorder
Interventions: CUD Treatment, Tobacco Treatment; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 3
States / cities: Concord, New Hampshire • Lebanon, New Hampshire • Seattle, Washington

Conditions: Opiate Dependence, Suicidal Ideation, Depression, Opioid Use, Opioid-Related Disorders, Opioid-use Disorder, Major Depressive Disorder
Interventions: Accelerated intermittent theta-burst stimulation (aiTBS); Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Depression, Substance Use
Interventions: Group CBT for Depression and AOD Disorders; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Gardena, California

Conditions: Substance Use Disorder, Cocaine Use Disorder
Interventions: Methylphenidate, Memory reconsolidation, Placebo; Drug · Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 26 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2031
U.S. locations: 1
States / cities: New York, New York

Conditions: Behavior, Health
Interventions: Computer-based Intervention; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 12 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 2
States / cities: Detroit, Michigan • Flint, Michigan

Conditions: Tobacco Use Disorder, Smoking
Interventions: Pharmacist-delivered group program for smoking cessation, Brief standard care session for smoking cessation delivered over the telephone; Other
Lead sponsor: University of Montana; Other
Eligibility: 21 Years and older
Enrollment: 101 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Missoula, Montana

Conditions: Nicotine Dependence
Interventions: Integrated Training for Smokers, Mindfulness Training for Smokers, Quitline; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 175 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: HIV, Mental Health, Substance Use
Interventions: NOLA GEM; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 4
States / cities: New Orleans, Louisiana

Conditions: Tobacco Dependence, Cigarette Craving, Smoking Behavior
Interventions: Exercise, passive control; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Stimulant Use, Human Immunodeficiency Virus (HIV), Depression
Interventions: ARTEMIS, Contingency management for Antiretroviral (ARV) adherence; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 59 Years
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: ADHD, Smoking
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 6 Years to 55 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder, Drinking, Alcohol, Substance Use
Interventions: Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI); Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Cincinnati, Ohio • Columbus, Ohio

Conditions: Tobacco Use Disorder
Interventions: Mindfulness-Oriented Recovery Enhancement (MORE), Cognitive Behavioral Therapy (CBT); Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 2
States / cities: Columbia, Missouri • Charleston, South Carolina

Conditions: Cigarette Smoking
Interventions: Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral, Nicotine replacement therapy - nicotine gum, Nicotine replacement therapy - nicotine lozenge, Bupropion Sustained Release, Varenicline, Combination pharmacotherapy - transdermal nicotine patch + nicotine gum, Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge, Combination pharmacotherapy - transdermal nicotine patch + bupropion, Alcohol use risk reduction, Behavioral activation for the treatment of depression, Behavioral management of post-cessation weight gain; Drug · Behavioral
Lead sponsor: Iowa City Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Substance Use Disorders, HIV Infections
Interventions: Virtual Reality Tool; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 15 Years to 30 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Depression, Anxiety, Suicidal Ideation, Substance Use
Interventions: Knowing Who You Are (Becoming): Cultural Identity Intervention; Behavioral
Lead sponsor: University of Alaska Anchorage; Other
Eligibility: 18 Years to 100 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Anchorage, Alaska

Conditions: Alcohol Use Disorder, Alcohol Associated Liver Disease, Medications for Alcohol Use Disorder, Behavioral Medicine, Medication Adherence
Interventions: AcamproSync; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Opioid Use Disorder (OUD), Chronic Pain
Interventions: Mindfulness text messages; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Tobacco Use Disorder
Interventions: Individual Rewards, Fixed Deposits, Chosen Deposits, Competitive Deposits (Pari-Mutuel), Usual Care; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking
Interventions: Tailored CBME Therapy via Technology, Standard of Care; Behavioral · Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 14 Years to 19 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Helping Poor Smokers Quit

NeuroControl of Nicotine Dependence

Kentucky Access to Recovery Evaluation

An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment

Clinical Trial Tobacco Marijuana

Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder

Group CBT for Depression and AOD Disorders

Targeting Drug Memories With Methylphenidate

Train Your Brain: A Pilot Project to Improve Memory and Decision Making

Randomized Trial Assessing the Effectiveness of a Pharmacist-Delivered Program for Smoking Cessation

Study Two on the Effectiveness of Mindfulness Training for Smokers

NOLA GEM: Feasibility and Acceptability of an MHealth Intervention for Violence-affected PLWH

Acute Effects of Exercise in Smokers With Schizophrenia

Project neuroARTEMIS

Family Risk Analysis of Substance Use in Attention Deficit Hyperactivity Disorder (ADHD) Youth Treated With Concerta

The STop UNhealthy Substance Use Now Trial

Smoking Cessation Behavioral Treatment Study

Tailored Tobacco Quitline for Rural Veterans

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health

A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease

Mindfulness Texting for Medication Adherence and Chronic Pain Management

Pilot Randomized Control Trial of Financial Incentives for Smoking Cessation

Korean Youth Smoking Cessation Study