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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:33 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1153–1176 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Tobacco Use Disorder
Interventions: electronic cigarette, nicotine inhaler; Other · Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Financial Hardship, Mental Health Issue, Substance Use
Interventions: Financial Capability Support with Peer Support Services; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 239 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Nicotine Addiction, Cigarette Smoking
Interventions: Nicotine, MR Compatible Nicotine Delivery Device; Drug · Device
Lead sponsor: Stony Brook University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
Interventions: Alcohol beverage, Placebo beverage; Other
Lead sponsor: University of Texas at Austin; Other
Eligibility: 21 Years to 26 Years
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Alcohol Use Disorder, Tobacco Smoking
Interventions: Lorcaserin Oral Tablet, Placebo oral tablet; Drug
Lead sponsor: The Mind Research Network; Other
Eligibility: 21 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Tobacco Use Disorder, Smoking Cessation, Tobacco Use Cessation
Interventions: Genetically-Informed RiskProfile, Brief Cessation Advice; Behavioral · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Substance-Related Disorders
Interventions: Letters; Other
Lead sponsor: University of Southern California; Other
Eligibility: Not listed
Enrollment: 851 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: San Diego, California

Conditions: Alcohol Consumption, Drug Abuse
Interventions: Brief motivational substance use intervention; Behavioral
Lead sponsor: RAND; Other
Eligibility: 12 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Alcohol Use Disorder
Interventions: Zonisamide, Placebo; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years to 70 Years
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 4
States / cities: Farmington, Connecticut • New Haven, Connecticut • West Haven, Connecticut + 1 more

Conditions: Substance Use Disorder (SUD), mHealth
Interventions: KulaMind-Recovery; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse, Child Neglect
Interventions: Wraparound; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 4
States / cities: Claremont, New Hampshire • Lebanon, New Hampshire

Conditions: Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence, Alcohol Abuse
Interventions: Real iTBS to the dlPFC, Sham iTBS to the dlPFC; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years to 65 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Nicotine Use Disorder
Interventions: E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1), E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2), E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2), E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2), E-liquid coolant (High [2.0%] WS-3) for non-menthol (3), E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3), E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3), E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4), E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4), E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4), E-liquid coolant (High [2.0%] WS-23) for non-menthol (5), E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5), E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5), E-liquid coolant (4% WS-23) for non-menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), E-liquid coolant (4% WS-23) for high (2.0%) menthol (6); Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Opioid-use Disorder, Mental Health Conditions
Interventions: Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 567 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Alcohol Dependence, Alcohol Drinking, Alcoholism, Alcohol Use Disorder, Addiction
Interventions: 7T MRI; Device
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 173 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Addiction, Substance Use Disorders (SUD)
Interventions: Holotropic breathwork, Multiple modality; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 3
States / cities: Lincoln, Nebraska • Omaha, Nebraska

Conditions: Nurse's Role, Stigma, Social, Implicit Bias
Interventions: ArtSpective; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 2
States / cities: Saint Cloud, Minnesota • Toledo, Ohio

Conditions: Substance Use, Psychopathy
Interventions: motivational enhancement therapy, standard care; Behavioral · Other
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Substance Use, Sexual Behavior, Adolescent Behavior
Interventions: Adapted FOY+ImPACT; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 13 Years to 16 Years
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Substance Use, Substance Use Disorders, Opioid-use Disorder, Peer Delivered, Medication for Opioid Use Disorder (MOUD), Methadone Treatment, Retention in Care, Behavioral Activation
Interventions: Peer-Delivered Behavioral Activation (Peer Activate); Behavioral
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Baltimore, Maryland • College Park, Maryland

Conditions: Serious Mental Illness, Tobacco Use Disorder
Interventions: Multi-component facilitation; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia, Alcohol Use Disorder (AUD), Suicide Ideation
Interventions: Deaf CBT-TS; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Smoking Cessation, Tobacco Use Disorder
Interventions: Nicotine patches, Telephone counseling, iQuit Smoking website; Drug · Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 2,485 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: PTSD, Substance Use Disorders
Interventions: Cognitive behavioral therapy for PTSD; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 3
States / cities: Tampa, Florida • Syracuse, New York • White River Junction, Vermont

Search by objective public record fields.

Electronic Cigarettes or Nicotine Inhaler for Smoking Cessation

Recovery Finance: Financial Health and Mental Health After Incarceration

Control Systems Approach to Predicting Individualized Dynamics of Nicotine Cravings

Familial Risk for Bipolar Disorder and Alcohol Sensitivity

Laboratory Screening of Lorcaserin for Alcohol Use Disorder

Implementation of Genomics in Substance Use Disorder Treatment

Behavioral Insights to Encourage Judicious Prescribing of Opioids

Brief Youth Substance Use Intervention for Primary Care

Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action

Connecting Loved Ones to Support and Empowering Recovery

Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes

Effect of Theta Burst Stimulation on Alcohol Cue Reactivity

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions

Behavioral and Functional Task Development, Implementation, and Testing

Group Activities to Support Addiction Recovery

Testing an Arts-based Program to Reduce Nurse Stigma Towards Perinatal Substance Use

The Impact of Psychopathic Traits on the Efficacy of a Substance Use Intervention

A Library-based Prevention Intervention for Adolescents Affected by Parental Drug Use

Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase

Facilitation to Increase Tobacco Treatment

Deaf CBT-TS to Reduce Suicide Risk

A Randomized Trial of Internet Access to Nicotine Patches

Cognitive Behavioral Therapy (CBT) for PTSD in Veterans With Co-Occurring SUDs