Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Tobacco Use Disorder
Interventions: bupropion and transdermal patch, transdermal patch and nicotine inhaler; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Suicide, Surveillance, Mental Health, Substance Use, Depressive Symptoms
Interventions: New Hope (NH), Elders Resilience (ER), Case Management (CM); Behavioral · Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 16 Years to 29 Years
Enrollment: 304 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Whiteriver, Arizona

Conditions: Nicotine Dependence, Bipolar Disorder
Interventions: Counseling/Healthy Lifestyle, Counseling/Managing Mood; Behavioral
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Alcohol Use Disorder, Family Members, Behavior, Addictive
Interventions: PartnerCHESS, ACHESS; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 398 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Substance-related Disorder
Interventions: Contingency Management, Case management; Behavioral · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Nicotine Dependence
Interventions: Text messaging prior to first counseling call, Text-to-Enhance, Mail Notice, Telephone Counseling; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 432 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 2
States / cities: San Diego, California • New York, New York

Conditions: HIV, Substance Use Disorders, Substance Use, AIDS
Interventions: CC PrTNER; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 15 Years to 29 Years · Male only
Enrollment: 275 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Baltimore, Maryland • Philadelphia, Pennsylvania

Conditions: Opioid Use Disorder
Interventions: Shared Decision Making Aid - Patients, Shared Decision Making Aid - Providers; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 100 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Depression, Substance Abuse, Substance Use, Neuroimaging, Dual Diagnosis
Interventions: Creatine monohydrate; Drug
Lead sponsor: Perry Renshaw; Other
Eligibility: 13 Years to 64 Years · Female only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Alcohol Use Disorder, HIV/AIDS, Hepatitis C, Binge Drinking
Interventions: Intervention: (Clinician's Guide + HealthCall for HIV/HCV); Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 99 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcohol Use Disorder (AUD), Alcohol-Related Disorders, Alcohol Use
Interventions: 0.3mg/kg/min Dimethyltryptamine + Normal Saline infusion, 0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion, 25 mg Diphenhydramine (5 min) + Normal Saline; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Dementia, Depression, Mood Disorder, Anxiety Disorder, Substance Use Disorder
Interventions: Psychiatric Consultation; Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: Sacramento, California • Woodland, California

Conditions: Nicotine Dependence
Interventions: Transcranial Magnetic Stimulation; Device
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Baltimore, Maryland • Catonsville, Maryland

Conditions: Alcohol Dependence, Alcoholism, Drug Dependence
Interventions: Chronic Disease Management for substance abuse, Standard care; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 569 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tobacco Use Disorder, Substance-Related Disorders
Interventions: Altered composition cigarette; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cannabis Use, Tobacco Use, Cigarette Smoking
Interventions: THC 30mg, THC 5mg, THC 0mg, Cigarette Full Nicotine, Cigarette Reduced Nicotine; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tobacco Dependence
Interventions: bupropion + nicotine gum, Active bupropion-Placebo gum, Placebo bupropion-Placebo gum; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 608 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2002
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Nicotine Vaping, Nicotine Dependence
Interventions: Nicotine, Placebo; Drug · Other
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Opioid Use, Opioid-use Disorder, Suicide
Interventions: OUD-CDS + Suicide Risk Model associated CDS; Other
Lead sponsor: HealthPartners Institute; Other
Eligibility: 18 Years to 75 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Bloomington, Minnesota

Conditions: Smoking, Tobacco Use Disorder
Interventions: Bupropion SR & Varenicline; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Nicotine Dependence, Tobacco Toxicity, Nicotine Dependence, Cigarettes, Cardiovascular Risk Factor, Nicotine Withdrawal
Interventions: SREC; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Stigma, Social, Behavior
Interventions: Stigma Awareness Training for Legal System Staff, Acceptance and Commitment Therapy for self-stigma; Behavioral
Lead sponsor: East Tennessee State University; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Johnson City, Tennessee

Conditions: Cocaine Use, Cocaine Dependence, Cocaine Use Disorder, Cocaine Use Disorder, Moderate, Cocaine Use Disorder, Severe
Interventions: Active H7-coil repetitive transcranial magnetic stimulation (rTMS), Sham H7-coil repetitive transcranial magnetic stimulation (rTMS); Device
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 22 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Methamphetamine Use Disorder
Interventions: Psilocybin 25 mg; Drug
Lead sponsor: Kevin Murnane; Other
Eligibility: 25 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Shreveport, Louisiana

Search by objective public record fields.

Non-Nicotine Agents for Smoking Cessation

Southwest Hub for American Indian Youth Suicide Prevention Research

Targeted Intervention for Bipolar Smokers

Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19

A Comprehensive Disease Management Program for Medically-Complex Substance Users

Text Messaging to Engage and Retain Veterans in Smoking Cessation Counseling

The Collaborative Care PrTNER Study

Stigma and a Shared Decision Aid

Creatine as a Treatment Option for Depression in Methamphetamine Using Females

Understanding and Intervening With Heavy Drinking Among Patients With HIV and HCV

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Pilot Study of Asynchronous and Synchronous Telepsychiatry for Skilled Nursing Facilities

Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction

Addiction Health Evaluation And Disease Management (AHEAD) Study

Behavioral Economic Purchasing Decisions for Cigarettes of Varied Compositions

Effect of Cannabis on Cigarette Use Behavior

Bupropion Alone or Combined With Nicotine Gum

Nicotine and Pavlovian Bias

Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0

Chantix & Bupropion for Smoking Cessation

Cigarette Harm Reduction With Electronic Cigarette Use

Reducing Stigma Among Individuals With Addiction and Staff in the Criminal Justice System

rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder

Psilocybin for Methamphetamine Addiction