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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:54 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1297–1320 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Substance Abuse
Interventions: Not listed
Lead sponsor: George Mason University; Other
Eligibility: 12 Years to 14 Years
Enrollment: 245 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 2
States / cities: New Haven, Connecticut • Fairfax, Virginia

Conditions: Tobacco Use Cessation, Tobacco Cessation, Tobacco Use Disorder, Tobacco Dependence, Tobacco-Use Disorder, Virus, Human Immunodeficiency
Interventions: Web-Based Tailored Smoking Cessation Intervention, Standard of Care; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Smoking, Nicotine Dependence, Nicotine Dependence, Other Tobacco Product
Interventions: electronic cigarette, cigarette group; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: HIV
Interventions: Observation; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 12 Years to 24 Years
Enrollment: 1,712 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 14
States / cities: Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 10 more

Conditions: Health Behaviors, Obesity, Substance Abuse, Anxiety, Depression
Interventions: Implementation of the MOHR assessment in primary care workflow; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 3,591 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 8
States / cities: Los Angeles, California • Chapel Hill, North Carolina • Portland, Oregon + 5 more

Conditions: Burnout, Compassion Satisfaction, Secondary Trauma
Interventions: PATH (Peer Advanced Training for total Health); Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Nicotine Dependence
Interventions: Chantix, Zyban, Nicotine patches; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 376 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 4
States / cities: Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more

Conditions: Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions: AD + Integrated Tobacco Order Set; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 1,044 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Substance Abuse, Decision Making, Shared, Implementation Science, Decision Making, Organizations, Substance-related Disorders, Policy
Interventions: Co-Design Sessions (CDS), Data products; Other
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 18 Years and older
Enrollment: 341 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Opioid Consumption, Postoperative, Pain After Surgery, Opioid Dependency
Interventions: Opioid tapering with CBT and education, Opioid tapering with education alone; Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Philadephia, Pennsylvania

Conditions: Opioid-use Disorder, Medication Adherence
Interventions: Youth Opioid Recovery Support (YORS); Behavioral
Lead sponsor: Potomac Health Foundations; Other
Eligibility: 18 Years to 28 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Depression, Anxiety, Substance Use Disorder (SUD), Post Traumatic Stress Disorder
Interventions: Microcurrent Neurofeedback (MCN), Standard Care for Substance Use Disorder; Device · Behavioral
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 18 Years to 65 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Tuscaloosa, Alabama

Conditions: Ride Sharing, Alcohol Drinking, Alcohol Intoxication, Drug Use, Motor Collision, Sexual Assault
Interventions: Not listed
Lead sponsor: Methodist Health System; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Anxiety Disorders, Substance Use Disorders
Interventions: CALM-SUD, Treatment as usual; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 60 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Substance-Related Disorders
Interventions: Computer Based Treatment; Behavioral
Lead sponsor: VA Connecticut Healthcare System; Federal
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Newington, Connecticut

Conditions: Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
Interventions: Not listed
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 21 Years to 30 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Champaign, Illinois

Conditions: Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome (FAS), Alcohol Related Neurodevelopmental Disorder, Alcohol Use Complicating Pregnancy, Unspecified Trimester
Interventions: Positive FASD education brochure, Negative FASD education brochure, Active comparator (a general women's health brochure); Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 422 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Alcohol Use Disorder, Alcohol Abuse, Alcoholism, Drinking Behavior, Drinking Problem
Interventions: Active Transcranial Magnetic Simulation, Sham; Device
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 25 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Alcohol Use Disorder (AUD)
Interventions: Mindfulness-Based Relapse Prevention; Behavioral
Lead sponsor: University of Georgia; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Macon, Georgia • Winder, Georgia

Conditions: Psychological Stress, Alcohol Intoxication
Interventions: Stress, Alcohol; Other
Lead sponsor: University of Washington; Other
Eligibility: 21 Years to 50 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression, Smoking
Interventions: Fluoxetine, Behavioral group smoking cessation treatment, Placebo; Drug · Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 247 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1998 – 2005
U.S. locations: 1
States / cities: Hines, Illinois

Conditions: Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
Interventions: LST High School Hybrid; Behavioral
Lead sponsor: National Health Promotion Associates, Inc.; Industry
Eligibility: 14 Years to 18 Years
Enrollment: 1,804 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Opioid Use Disorder, Cigarette Smoking
Interventions: Telehealth Motivational Counseling, Nicotine Replacement Product, National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).; Behavioral · Drug · Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 75 Years
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: New York, New York • The Bronx, New York

Conditions: Substance Use Disorders, Substance Use, Substance Dependence
Interventions: MI-CBT Teletx; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 75 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

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Parent-Adolescent Interactions and Adolescent Development

Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV

A Trial of E-cigarettes in Current Cigarette Smokers

Managerial Database II

Goal Setting for Health Behavior and Psychosocial Issues in Primary Care

PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R61 Phase Pilot)

Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers

Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized Smokers

Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Overdose Prevention

Preoperative Opioid Tapering Before Spine Surgery

The Youth Opioid Recovery Support (YORS) Intervention

Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders

The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents

Delivery of Anxiety Disorder Treatment in Addictions Centers

Computer-Based Training in Cognitive Behavior Therapy (CBT4CBT)

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study

Development of Education Materials for Prevention of FAS in Russia

Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder

Renewed Recovery: a Pilot Test of a Web-Based Mindfulness-Based Relapse Prevention Continuing Care Intervention for Alcohol Use Disorder

Stress-motivated Alcohol Use as a Value-based Decision-making Process

Fluoxetine as a Quit Smoking Aid for Depression-Prone Smokers

A High School Program for Preventing Prescription Drug Misuse

E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD)