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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:52 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1345–1368 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Mild to Heavy Alcohol Consumption
Interventions: Oxycodone; Other
Lead sponsor: University of Washington; Other
Eligibility: 35 Years and older
Enrollment: 128 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid Use Disorder, Opioid Use
Interventions: Sub-acute stabilization; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 40,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid Use Disorder, Medication Adherence, Polysubstance Drug Use (Indiscriminate Drug Use), Methamphetamine-dependence
Interventions: Patient Navigation and mHealth (PN+mHealth); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Antisocial Personality Disorder, Substance Use Disorder
Interventions: Moral Reconation Therapy (MRT); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 3
States / cities: North Little Rock, Arkansas • Palo Alto, California • Bedford, Massachusetts

Conditions: Smoking Cessation
Interventions: GENERIC, eTARGET; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 2,896 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Substance Use Disorders, Posttraumatic Stress Disorder
Interventions: Written Exposure Therapy, Neutral Topic Writing; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Suicide, Suicide, Attempted, Suicidal Ideation, Alcohol Use Disorder, Alcoholism, Alcohol Abuse, Screening and Brief Interventions
Interventions: WisePath for Adults, Active-Control app + electronic wellness resources brochure; Device
Lead sponsor: Evidence-Based Practice Institute, Seattle, WA; Industry
Eligibility: 22 Years and older
Enrollment: 127 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid Use Disorder
Interventions: Supervised Exercise Intervention; Other
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 64 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Tobacco Use Disorder
Interventions: Progesterone, sugar pill; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Bipolar Depression
Interventions: acetyl-l-carnitine PLUS alpha-lipoic acide, Placebo; Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Opioid Abuse, Unspecified
Interventions: Opioid Naive, OR, At-risk for long-term use, OR, Long-term opioid recipient; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 555 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Substance Use Disorders
Interventions: Intensive Outpatient Treatment (IOP) + Contingency Management (CM), Working Memory Training; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 12 Years to 26 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sleep, Neurobehavioral Manifestations
Interventions: Ethanol (Bourbon or Vodka); Drug
Lead sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA); NIH
Eligibility: 21 Years to 30 Years
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
Interventions: Alcohol vs. Placebo beverage conditions; Other
Lead sponsor: University of Texas at Austin; Other
Eligibility: 21 Years to 26 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Nicotine Dependence, Tobacco Smoking
Interventions: Oxytocin, Placebo; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 40 Years
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Smoking Cessation, Substance Use Disorder
Interventions: Intensive Referral Intervention Group, Standard Practice Facilitated Group; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Tobacco Smoking
Interventions: Ketamine, Midazolam, Dexmedetomidine, Saline; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Insomnia, Alcohol Use, Unspecified, Marijuana Use
Interventions: Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 24 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid-use Disorder, Medication Assisted Treatment, Substance Use Disorders
Interventions: Mindfulness based relapse prevention and peer mentoring; Behavioral
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 19 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Birmingham, Alabama • Homewood, Alabama

Conditions: Smoking Cessation
Interventions: Telephone Counseling, Nicotine Patches; Behavioral · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: San Diego, California

Conditions: Opioid Use Disorder
Interventions: Naloxone Nasal Spray; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tobacco Use Disorder, Smoking Cessation, Lung Cancer
Interventions: p16 Methylation and Lung Cancer Education; Behavioral
Lead sponsor: Duke University; Other
Eligibility: Not listed
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Nicotine Dependence, Smoking Cessation
Interventions: EVP-6124, Placebo Capsule, NicoDerm Patch (Active), NRT Patch (Placebo), Brief Supportive and Behavioral Treatment; Drug · Behavioral
Lead sponsor: A. Eden Evins; Other
Eligibility: 18 Years to 65 Years
Enrollment: 345 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anxiety Disorder, Posttraumatic Stress Disorder, Hazardous Drinking
Interventions: Unified Protocol- Alcohol, Usual care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Search by objective public record fields.

Cognitive, Behavioral and Aging Effects of Pain Medication in Alcohol Users

Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level Data

MHealth Incentivized Adherence Plus Patient Navigation

Justice-Involved Veterans and Moral Reconation Therapy

Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes

Written Exposure Therapy for Veterans With SUD and PTSD

Drivers of Suicide Mobile App Study

Healthy Aging Through Movement

Effect of Progesterone on Smoking Behavior in Male and Female Smokers

The Use of a Mitochondrial Enhancement Treatment in Bipolar Disorder

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges

Behavioral Treatment of Adolescent Substance Use

Hangover, Congeners, Sleep and Occupational Performance

Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study

Effects of Intranasal Oxytocin on Cigarette Smoking

Intensive Referral to Reduce Smoking in Probationers

The Effects of Sedatives on Tobacco Use Disorder Version 2

Research Evaluating Sleep & Trends for Universal Prevention

Minds and Mentors Program (MiMP)- R61

Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch Messaging

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl

p16 Methylation for Smoking Cessation

A Safety and Cognitive Function Study of EVP-6124 Versus Placebo in Subjects With Nicotine Dependence

Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use