Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:01 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Alcoholism, Nicotine Dependence
Interventions: Varenicline; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cocaine Dependence
Interventions: Behavioral Incentives, Education Control; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking
Interventions: Naltrexone Hydrochloride, Transdermal Nicotine; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 1998 – 2001
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression, Anxiety, Opioid-Related Disorders, Pain, Chronic
Interventions: More Individualized Care: Assessment and Recovery through Engagement (MI-CARE); Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 805 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Indianapolis, Indiana • Seattle, Washington

Conditions: Alcohol Use Disorder, Couples
Interventions: Oxytocin, Placebo; Drug · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 75 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcohol Consumption, Alcohol Use Disorder
Interventions: Step Away Chatbot, Step Away App; Behavioral
Lead sponsor: University of Alaska Anchorage; Other
Eligibility: 18 Years and older
Enrollment: 191 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Anchorage, Alaska

Conditions: Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions: Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO); Behavioral
Lead sponsor: Partnership to End Addiction; Other
Eligibility: 21 Years to 75 Years
Enrollment: 730 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression, Suicide
Interventions: Intensive Outpatient CBT, Standard Care; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 12 Years to 18 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Anxiety, Depression, Alcohol Use Disorder
Interventions: Positive affect training; Behavioral
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Cocaine-Related Disorders, Substance-Related Disorders
Interventions: quetiapine; Drug
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 65 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Alcohol Use Disorder, Risky Health Behavior
Interventions: Female-Specific Cognitive Behavioral Therapy (FS-CBT), Usual Care; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older · Female only
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking
Interventions: Standard Behavioral Therapy, Mindfulness Based Addiction Therapy; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Substance Use, Healthy
Interventions: fMRI, Questionnaires and surveys, Behavioral tasks and eye tracking; Device · Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 22 Years
Enrollment: 294 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Ann Arbor, Michigan

Conditions: Alcohol Use Disorder, Posttraumatic Stress Disorder
Interventions: Behavioral Activation (BA), Relapse Prevention (RP); Behavioral
Lead sponsor: RTI International; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Use Disorder
Interventions: Cigarettes with varying nicotine content, E-Cigarettes; Other
Lead sponsor: University of Vermont; Other
Eligibility: 21 Years to 70 Years
Enrollment: 326 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Nicotine Use Disorder
Interventions: Practice Quit Attempt; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 45 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Copd, Smoking Cessation, Nicotine Dependence, Tobacco Use, Cigarette Smoking
Interventions: Unified Protocol adapted for smoking cessation, American Lung Association self-management strategies for smoking cessation; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Smoking, Nicotine Dependence, Alcohol Dependence
Interventions: Practical Counseling, Alcohol Intervention Counseling; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 1,948 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Opioid Use Disorder
Interventions: Talk About It (conversation aid); Behavioral
Lead sponsor: Baystate Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: HIV, Opiate Dependence
Interventions: Abstinence-reinforcing contingency management intervention, Performance Feedback intervention; Behavioral
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 3
States / cities: The Bronx, New York

Conditions: Tobacco Use Cessation
Interventions: Counseling, Contingency management, Nicotine patches; Other · Behavioral · Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: HIV/AIDS, Depression, Anxiety, Post-traumatic Stress Disorder, Substance Use Disorders
Interventions: Adapted Common Elements Treatment Approach; Behavioral
Lead sponsor: Michael J Mugavero, MD; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Alcohol Drinking, Tobacco Use, Substance Use, Sexual Behavior
Interventions: Journey of Transformation-Native Youth Health Leadership Program curriculum; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 13 Years to 16 Years
Enrollment: 182 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders, Substance-Related Disorders
Interventions: SUCCEEDS Program, Living a Healthy College Lifestyle; Behavioral
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 18 Years to 24 Years
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: College Park, Maryland

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Varenicline and Alcohol in Inpatient Addictions Program (IAP)

Behavioral Incentives to Increase Exercise in Cocaine Dependent Women

Naltrexone and Patch for Smokers

More Individualized Care: Assessment and Recovery Through Engagement

Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)

Step Away: Comparing a Chatbot-delivered Alcohol Intervention With a Smartphone App

Messaging Interventions to Reduce Alcohol Problems Project

Intensive Outpatient Services for Teens

Affective Modulation of Positivity for Alcohol Use Disorder

Quetiapine for Cocaine Use and Cravings

A Female-Specific CBT Group for Veteran Women With Alcohol Use Disorder in VA Primary Care Settings

Healthier Hearts and Brains in Treating Smoking: The HABITS Study

Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model

Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttraumatic Stress Disorder

Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder

Neural Basis of Eating Behavior in Abstinent Smokers

Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study

Alcohol Counseling for Telephone Quitline Callers

Aim 2 - Conversations Can Save Lives: TALKing About Buprenorphine & Methadone for Opioid Use Treatment Initiation

Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment

Low-Cost Contingency Management for Smoking Cessation

Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States

Journey of Transformation Curriculum for Native American Youth

Helping College Students With ADHD Lead Healthier Lifestyles