- Conditions
- Substance Use Disorders, Posttraumatic Stress Symptom, Anxiety
- Interventions
- Safe and Sound Protocol
- Device
- Lead sponsor
- Caron Treatment Centers
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Wernersville, Pennsylvania
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Showing 1–24
of 97
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Computer-assisted, Evidence-based Psychosocial Intervention, for Substance Abuse Treatment
- Interventions
- Therapeutic Education System (TES), Standard Care
- Behavioral
- Lead sponsor
- National Development and Research Institutes, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 376 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 10
- States / cities
- Cañon City, Colorado • Denver, Colorado • Model, Colorado + 5 more
- Conditions
- Schizophrenia Disorder, Schizoaffective Disorder, Bipolar Disorder (BD), Substance Use Disorder (SUD)
- Interventions
- Financial incentives for adherence to long-acting injectable medication, Standard of care with monthly surveys
- Behavioral
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 5
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Addiction, Substance Use Disorders (SUD)
- Interventions
- Holotropic breathwork, Multiple modality
- Behavioral
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Lincoln, Nebraska
- Conditions
- Substance Use Disorder (SUD)
- Interventions
- TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
- Behavioral · Other
- Lead sponsor
- Michele Staton
- Other
- Eligibility
- 18 Years to 99 Years · Female only
- Enrollment
- 264 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 4
- States / cities
- Frankfort, Kentucky • Pewee Valley, Kentucky • Chillicothe, Missouri + 1 more
- Conditions
- Tobacco Use Disorder, Substance Use Disorder (SUD)
- Interventions
- Contingency Management (CM), Treatment as Usual (TAU)
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- HIV, Substance Use Disorder (SUD)
- Interventions
- Wellness, Intervention Strategies and HIV Care (WISH), Movie Night Club - Attention and Time Matched Control
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Oakland, California • San Francisco, California
- Conditions
- Substance Use Disorders, Posttraumatic Stress Disorder
- Interventions
- Written Exposure Therapy, Neutral Topic Writing
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Bipolar Disorder
- Interventions
- Senyo Health App
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Cannabis Use, Substance Use Disorder (SUD), Healthy
- Interventions
- Placebo Oral Capsule, THC
- Drug
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years to 21 Years
- Enrollment
- 144 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Alcohol Use Disorder (AUD), Substance Use Disorders
- Interventions
- W-SUDs, Digitally-delivered Psychoeducation
- Device · Other
- Lead sponsor
- Woebot Health
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 258 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Gambling, Alcohol Consumption, Cannabis
- Interventions
- Personalized Feedback Intervention
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 17 Years to 24 Years
- Enrollment
- 361 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Substance Use Disorders, Behavioral Health, Addiction Psychological, Addiction Disorders, Meditation, Mindfulness Based Stress Reduction, Prevention
- Interventions
- Mindfulness and Meditation-Based Relapse Prevention Program
- Behavioral
- Lead sponsor
- Bout Me Healing
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Boca Raton, Florida
- Conditions
- Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
- Interventions
- Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist
- Other
- Lead sponsor
- Texas Christian University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,620 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Prisoners, Substance Use History, Chronic Medical Conditions, Psychiatric Condition, Substance Use Disorder (SUD)
- Interventions
- In-person visit with study team member, In-person visit with NCM, Phone calls and texts, Phone calls and texts - NCM
- Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 488 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Substance Use Disorders
- Interventions
- Smartphone app
- Device
- Lead sponsor
- BrightView LLC
- Industry
- Eligibility
- Not listed
- Enrollment
- 108 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Substance Use Disorder (SUD), Opioid Use Disorder (OUD)
- Interventions
- Deep Brain Stimulation
- Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2031
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Posttraumatic Stress Disorder, Alcohol Use Disorders
- Interventions
- doxazosin, placebo
- Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- Not listed
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Concussion, Mild Traumatic Brain Injury, Brain Injury, Traumatic Brain Injury, Substance Use, Substance Use Disorder (SUD)
- Interventions
- Integrated Model of Care
- Other
- Lead sponsor
- Shepherd Center, Atlanta GA
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Alcohol Use Disorder, Posttraumatic Stress Disorder (PTSD)
- Interventions
- Prazosin, Naltrexone, Placebo (Prazosin), Placebo (Naltrexone)
- Drug
- Lead sponsor
- Seattle Institute for Biomedical and Clinical Research
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Drug Use Disorders, Alcohol-Related Disorders, Substance Use Disorder (SUD)
- Interventions
- Care Navigation
- Behavioral
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), Substance Use Disorder (SUD)
- Interventions
- N-acetylcysteine, Placebo, Cognitive behavioral therapy
- Drug · Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 2
- States / cities
- Charleston, South Carolina
- Conditions
- Substance Use Disorder (SUD)
- Interventions
- none, there is no intervention in this study
- Other
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Substance Use Disorders, Posttraumatic Stress Disorder
- Interventions
- Modified Seeking Safety integrated into std outpatient SUD care, Standard outpatient SUD care
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 117 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Palo Alto, California