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ClinicalTrials.gov public records Last synced Oct 30, 2026, 7:33 PM EDT

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Showing 193–211 of 211 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Substance Use Risks Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effective Caregiving for Neonatal Abstinence Syndrome: Testing an Instructional Mobile Technology Platform for High-Risk Pregnant Women

NCT04783558
View directory record Official record
Conditions
Neonatal Abstinence Syndrome, Opioid-use Disorder
Interventions
Mobile-based NAS Caregiving Tool
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Oct 30, 2026, 7:33 PM EDT
Not yet recruiting Not applicable Interventional

Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior

NCT07769580
View directory record Official record
Conditions
HIV, Risk Behavior, Alcohol Abuse
Interventions
CLT- Concrete text messages, CLT- Abstract text messages, Control messages, No messages, GamePlan Online Program
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 30, 2026, 7:33 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessing the Link Between Smoke Carcinogen Biomarkers and Lung Cancer Risk - 1

NCT00218179
View directory record Official record
Conditions
Tobacco Use Disorder, Lung Cancer
Interventions
Non-intervention
Other
Lead sponsor
University of Minnesota
Other
Eligibility
55 Years to 74 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project RAP: Family-based HIV Prevention in the Juvenile Drug Court

NCT01403298
View directory record Official record
Conditions
HIV/AIDS
Interventions
Family-Based HIV prevention, Adolescent Only Health Promotion
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes

NCT04637581
View directory record Official record
Conditions
Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse, Child Neglect
Interventions
Wraparound
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
4
States / cities
Claremont, New Hampshire • Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional

Improving Sleep to Reduce Risk for Substance Use Disorder

NCT03226132
View directory record Official record
Conditions
Substance Use Disorders, Insomnia, Posttraumatic Stress Disorder
Interventions
Brief Behavioral Therapy for Insomnia, Repeated Contact
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Oct 30, 2026, 7:33 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Regional Partnership to Improve Outcomes Through Fatherhood Engagement

NCT05562557
View directory record Official record
Conditions
Substance Use, Child Abuse, Child Neglect, Fathers, Father-Child Relations
Interventions
Motivational Enhancement, HERO Dads Fatherhood Program, Contingency Management, Case Management
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 30, 2026, 7:33 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Family Risk Analysis of Substance Use in Attention Deficit Hyperactivity Disorder (ADHD) Youth Treated With Concerta

NCT00181792
View directory record Official record
Conditions
ADHD, Smoking
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2012 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Familial Risk for Bipolar Disorder and Alcohol Sensitivity

NCT04716036
View directory record Official record
Conditions
Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
Interventions
Alcohol beverage, Placebo beverage
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
21 Years to 26 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional

Developing an Intervention to Address Suicide Risk During Substance Use Disorder

NCT01127932
View directory record Official record
Conditions
Suicide, Substance-Related Disorders
Interventions
Psychoeducation for substance abuse, CBT for suicide in Substance abuse
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Waterford, Michigan
Source: ClinicalTrials.gov public record
Updated May 13, 2015 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Phase 3 Interventional

EEG/Event-related Brain Potential Risk Markers as Predictors and Outcomes of SUD Treatment in Adolescents

NCT02016378
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Bias retraining, Sham retraining
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Phase 4 Interventional Results available

Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder

NCT04170738
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Substance Abuse
Interventions
Adderall
Drug
Lead sponsor
Jeffrey Newcorn
Other
Eligibility
7 Years to 12 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Yoga for Substance Use Risk Factors in a School Setting

NCT01821950
View directory record Official record
Conditions
Adolescent Development
Interventions
Yoga during physical education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
11 Years to 14 Years
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 30, 2026, 7:33 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Piloting ProHealth: A Program for Male Soldiers on Sex, Dating and Alcohol-Use at Fort Bragg

NCT03184298
View directory record Official record
Conditions
Sexual Assault and Rape, Risk Behavior, Alcohol Abuse
Interventions
Surveys, Interviews, Group Discussions
Other
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 26 Years · Male only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women

NCT00619320
View directory record Official record
Conditions
HIV Infections, Substance Use
Interventions
Safer Sex Skills Building (SSB)
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older · Female only
Enrollment
380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
2
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2013 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0

NCT04939727
View directory record Official record
Conditions
Opioid Use, Opioid-use Disorder, Suicide
Interventions
OUD-CDS + Suicide Risk Model associated CDS
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Not applicable Interventional

Risk Reduction for Drug Use and Sexual Revictimization

NCT00998153
View directory record Official record
Conditions
Risk Reduction Through Family Therapy, Usual Care
Interventions
Risk Reduction through Family Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Phase 2 Interventional Results available

Onsite Buprenorphine Treatment at Syringe Exchange Programs

NCT03150173
View directory record Official record
Conditions
Opiate Addiction
Interventions
Onsite treatment, Enhanced referral, Buprenorphine
Behavioral · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 30, 2026, 7:33 PM EDT
Completed Phase 3 Interventional

Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE)

NCT05790252
View directory record Official record
Conditions
Opioid Use Disorder, Pregnancy Related, Pregnancy, High Risk, Pregnancy Complications, Buprenorphine Withdrawal
Interventions
Buprenorphine Transdermal Matrix Patch, Sham patch
Drug · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 110 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 30, 2026, 7:33 PM EDT